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C9JNR5

- C9JNR5_HUMAN

UniProt

C9JNR5 - C9JNR5_HUMAN

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Protein
Submitted name:

Insulin B chain

Gene
INS
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver By similarity.SAAS annotations

Keywords - Molecular functioni

HormoneSAAS annotations

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolismSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin B chainImported
Gene namesi
Name:INSImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:6081. INS.

Subcellular locationi

Secreted By similarity SAAS annotations

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotations

Pathology & Biotechi

Protein family/group databases

Allergomei2121. Hom s Insulin.

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

ArrayExpressiC9JNR5.
BgeeiC9JNR5.

Interactioni

Subunit structurei

Heterodimer of a B chain and an A chain linked by two disulfide bonds By similarity.SAAS annotations

Structurei

3D structure databases

ProteinModelPortaliC9JNR5.
SMRiC9JNR5. Positions 25-54.

Family & Domainsi

Phylogenomic databases

OMAiLLHRERW.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR004825. Insulin.
IPR016179. Insulin-like.
[Graphical view]
PfamiPF00049. Insulin. 1 hit.
[Graphical view]
PRINTSiPR00277. INSULIN.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9JNR5-1 [UniParc]FASTAAdd to Basket

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MALWMRLLPL LALLALWGPD PAAAFVNQHL CGSHLVEALY LVCGERGFFY   50
TPKTRREAED LQAGELLQLD AARRQPHTRR LLHRERWNKA LE 92
Length:92
Mass (Da):10,631
Last modified:November 3, 2009 - v1
Checksum:i4E099F7685F10D39
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei92 – 921Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC132217 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000421783; ENSP00000408400; ENSG00000254647.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC132217 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali C9JNR5.
SMRi C9JNR5. Positions 25-54.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 2121. Hom s Insulin.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000421783 ; ENSP00000408400 ; ENSG00000254647 .

Organism-specific databases

HGNCi HGNC:6081. INS.
GenAtlasi Search...

Phylogenomic databases

OMAi LLHRERW.

Miscellaneous databases

NextBioi 35487199.

Gene expression databases

ArrayExpressi C9JNR5.
Bgeei C9JNR5.

Family and domain databases

Gene3Di 1.10.100.10. 1 hit.
InterProi IPR004825. Insulin.
IPR016179. Insulin-like.
[Graphical view ]
Pfami PF00049. Insulin. 1 hit.
[Graphical view ]
PRINTSi PR00277. INSULIN.
SMARTi SM00078. IlGF. 1 hit.
[Graphical view ]
SUPFAMi SSF56994. SSF56994. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9JNR5_HUMAN
AccessioniPrimary (citable) accession number: C9JNR5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 3, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi