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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

GPD1L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:GPD1LImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000152642.10.
HGNCiHGNC:28956. GPD1L.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000152642.

PTM / Processingi

Proteomic databases

MaxQBiC9JM46.
PeptideAtlasiC9JM46.
PRIDEiC9JM46.

Expressioni

Gene expression databases

BgeeiENSG00000152642.
ExpressionAtlasiC9JM46. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JM46.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 76NAD_Gly3P_dh_NInterPro annotationAdd BLAST70
Domaini81 – 127NAD_Gly3P_dh_NInterPro annotationAdd BLAST47
Domaini148 – 172NAD_Gly3P_dh_CInterPro annotationAdd BLAST25

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000003114.
HOGENOMiHOG000246855.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH-like_C_sf.
IPR013328. 6PGD_dom2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 2 hits.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9JM46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAPLKVCI VGSGNWGSAV AKIIGNNVKK LQKFASTVKM WVFEETVNGR
60 70 80 90 100
KLTDIINNDH ENVKYLPGHK LPENVGIDEG PEGLKLISDI IREKMGIDIS
110 120 130 140 150
VLMGANIANE VAAEKFCETT IGSKVMENGL LFKELLQTPN FRITVVDDAD
160 170
TVELCGALKN IVAVGAGFCD GLR
Length:173
Mass (Da):18,643
Last modified:November 3, 2009 - v1
Checksum:iE5744F128E68B61B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei173Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC094019 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000425459; ENSP00000408770; ENSG00000152642.
UCSCiuc062hup.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9JM46_HUMAN
AccessioniPrimary (citable) accession number: C9JM46
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: December 20, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported