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C9JLW8

- F195B_HUMAN

UniProt

C9JLW8 - F195B_HUMAN

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Protein

Protein FAM195B

Gene

FAM195B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM195B
Gene namesi
Name:FAM195B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:28007. FAM195B.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165431912.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9797Protein FAM195BPRO_0000393954Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei21 – 211Phosphoserine2 Publications
Modified residuei24 – 241Phosphoserine1 Publication
Modified residuei41 – 411PhosphotyrosineBy similarity
Modified residuei79 – 791N6-acetyllysine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiC9JLW8.
PaxDbiC9JLW8.
PRIDEiC9JLW8.

PTM databases

PhosphoSiteiC9JLW8.

Expressioni

Gene expression databases

BgeeiC9JLW8.
ExpressionAtlasiC9JLW8. baseline.

Organism-specific databases

HPAiHPA045542.

Interactioni

Protein-protein interaction databases

BioGridi131518. 3 interactions.

Structurei

3D structure databases

ProteinModelPortaliC9JLW8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM195 family.Curated

Phylogenomic databases

eggNOGiNOG41066.
GeneTreeiENSGT00530000064168.
HOGENOMiHOG000035119.
InParanoidiC9JLW8.
OrthoDBiEOG7RRF8X.
PhylomeDBiC9JLW8.
TreeFamiTF326620.

Family and domain databases

InterProiIPR029428. FAM195.
[Graphical view]
PfamiPF14799. FAM195. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9JLW8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSSPVSRVV YNGKRTSSPR SPPSSSEIFT PAHEENVRFI YEAWQGVERD
60 70 80 90
LRGQVPGGER GLVEEYVEKV PNPSLKTFKP IDLSDLKRRS TQDAKKS
Length:97
Mass (Da):10,920
Last modified:November 3, 2009 - v1
Checksum:iD92176E755159A81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125584 mRNA. Translation: BAC86211.1. Sequence problems.
AC174470 Genomic DNA. No translation available.
CH471099 Genomic DNA. Translation: EAW89687.1.
CCDSiCCDS45814.1.
RefSeqiNP_001087236.1. NM_001093767.2.
NP_997251.2. NM_207368.4.
UniGeneiHs.514632.

Genome annotation databases

EnsembliENST00000455127; ENSP00000409009; ENSG00000225663.
ENST00000538396; ENSP00000445543; ENSG00000225663.
ENST00000574190; ENSP00000458720; ENSG00000225663.
ENST00000576730; ENSP00000458707; ENSG00000225663.
GeneIDi348262.
KEGGihsa:348262.
UCSCiuc010wuy.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125584 mRNA. Translation: BAC86211.1 . Sequence problems.
AC174470 Genomic DNA. No translation available.
CH471099 Genomic DNA. Translation: EAW89687.1 .
CCDSi CCDS45814.1.
RefSeqi NP_001087236.1. NM_001093767.2.
NP_997251.2. NM_207368.4.
UniGenei Hs.514632.

3D structure databases

ProteinModelPortali C9JLW8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 131518. 3 interactions.

PTM databases

PhosphoSitei C9JLW8.

Proteomic databases

MaxQBi C9JLW8.
PaxDbi C9JLW8.
PRIDEi C9JLW8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000455127 ; ENSP00000409009 ; ENSG00000225663 .
ENST00000538396 ; ENSP00000445543 ; ENSG00000225663 .
ENST00000574190 ; ENSP00000458720 ; ENSG00000225663 .
ENST00000576730 ; ENSP00000458707 ; ENSG00000225663 .
GeneIDi 348262.
KEGGi hsa:348262.
UCSCi uc010wuy.1. human.

Organism-specific databases

CTDi 348262.
GeneCardsi GC17M079783.
H-InvDB HIX0014255.
HGNCi HGNC:28007. FAM195B.
HPAi HPA045542.
neXtProti NX_C9JLW8.
PharmGKBi PA165431912.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG41066.
GeneTreei ENSGT00530000064168.
HOGENOMi HOG000035119.
InParanoidi C9JLW8.
OrthoDBi EOG7RRF8X.
PhylomeDBi C9JLW8.
TreeFami TF326620.

Miscellaneous databases

GenomeRNAii 348262.
NextBioi 99380.
PROi C9JLW8.

Gene expression databases

Bgeei C9JLW8.
ExpressionAtlasi C9JLW8. baseline.

Family and domain databases

InterProi IPR029428. FAM195.
[Graphical view ]
Pfami PF14799. FAM195. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Small intestine.
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  5. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-79, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  7. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21 AND SER-24, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiF195B_HUMAN
AccessioniPrimary (citable) accession number: C9JLW8
Secondary accession number(s): Q6ZUL0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: November 3, 2009
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3