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Protein
Submitted name:

Isocitrate dehydrogenase [NADP] cytoplasmic

Gene

IDH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase [NADP] cytoplasmicImported
Gene namesi
Name:IDH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000138413.13
HGNCiHGNC:5382 IDH1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000138413

PTM / Processingi

Proteomic databases

PeptideAtlasiC9JLU6
PRIDEiC9JLU6

Expressioni

Gene expression databases

BgeeiENSG00000138413
ExpressionAtlasiC9JLU6 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 73Iso_dhInterPro annotationAdd BLAST63

Phylogenomic databases

eggNOGiKOG1526 Eukaryota
COG0538 LUCA
GeneTreeiENSGT00390000012547
HOGENOMiHOG000213530

Family and domain databases

InterProiView protein in InterPro
IPR004790 Isocitrate_DH_NADP
IPR024084 IsoPropMal-DH-like_dom
PANTHERiPTHR11822 PTHR11822, 1 hit
PfamiView protein in Pfam
PF00180 Iso_dh, 1 hit

Sequencei

Sequence statusi: Fragment.

C9JLU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKKISGGSV VEMQGDEMTR IIWELIKEKL IFPYVELDLH SYDLGIENRD
60 70
ATNDQVTKDA AEAIKKHNVG VKC
Length:73
Mass (Da):8,250
Last modified:October 5, 2016 - v8
Checksum:i9B3465E0D9ADCF4A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei73Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016697 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000417583; ENSP00000409045; ENSG00000138413
UCSCiuc061rwv.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JLU6_HUMAN
AccessioniPrimary (citable) accession number: C9JLU6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: March 28, 2018
This is version 64 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health