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Protein
Submitted name:

Rho GTPase-activating protein 4

Gene

ARHGAP4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Rho GTPase-activating protein 4Imported
Gene namesi
Name:ARHGAP4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:674. ARHGAP4.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000089820.

PTM / Processingi

Proteomic databases

MaxQBiC9JLA8.
PaxDbiC9JLA8.
PeptideAtlasiC9JLA8.
PRIDEiC9JLA8.

Expressioni

Gene expression databases

BgeeiENSG00000089820.
ExpressionAtlasiC9JLA8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000359045.

Structurei

3D structure databases

ProteinModelPortaliC9JLA8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 174F-BARInterPro annotationAdd BLAST174

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili127 – 168Sequence analysisAdd BLAST42

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410INNV. Eukaryota.
ENOG410YF76. LUCA.
GeneTreeiENSGT00760000118863.
HOGENOMiHOG000202771.

Family and domain databases

InterProiView protein in InterPro
IPR027267. AH/BAR-dom.
IPR031160. F_BAR.
IPR001060. FCH_dom.
PfamiView protein in Pfam
PF00611. FCH. 1 hit.
SMARTiView protein in SMART
SM00055. FCH. 1 hit.
SUPFAMiSSF103657. SSF103657. 1 hit.
PROSITEiView protein in PROSITE
PS51741. F_BAR. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9JLA8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRWQLSEQLR CLELQGELRR ELLQELAEFM RRRAEVELEY SRGLEKLAER
60 70 80 90 100
FSSRGGRLGS SREHQSFRKE PSLLSPLHCW AVLLQHTRQQ SRESAALSEV
110 120 130 140 150
LAGPLAQRLS HIAEDVGRLV KKSRDLEQQL QDELLEVVSE LQTAKKTYQA
160 170
YHMESVNAEA KLREAERQEE KRAG
Length:174
Mass (Da):20,236
Last modified:November 3, 2009 - v1
Checksum:iC62571CB681F468E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei174Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF510182 Genomic DNA. No translation available.
KF510654 Genomic DNA. No translation available.
KF510656 Genomic DNA. No translation available.
U52112 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000422091; ENSP00000413782; ENSG00000089820.
UCSCiuc065bzc.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF510182 Genomic DNA. No translation available.
KF510654 Genomic DNA. No translation available.
KF510656 Genomic DNA. No translation available.
U52112 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliC9JLA8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000359045.

Proteomic databases

MaxQBiC9JLA8.
PaxDbiC9JLA8.
PeptideAtlasiC9JLA8.
PRIDEiC9JLA8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000422091; ENSP00000413782; ENSG00000089820.
UCSCiuc065bzc.1. human.

Organism-specific databases

HGNCiHGNC:674. ARHGAP4.
OpenTargetsiENSG00000089820.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410INNV. Eukaryota.
ENOG410YF76. LUCA.
GeneTreeiENSGT00760000118863.
HOGENOMiHOG000202771.

Miscellaneous databases

ChiTaRSiARHGAP4. human.

Gene expression databases

BgeeiENSG00000089820.
ExpressionAtlasiC9JLA8. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR027267. AH/BAR-dom.
IPR031160. F_BAR.
IPR001060. FCH_dom.
PfamiView protein in Pfam
PF00611. FCH. 1 hit.
SMARTiView protein in SMART
SM00055. FCH. 1 hit.
SUPFAMiSSF103657. SSF103657. 1 hit.
PROSITEiView protein in PROSITE
PS51741. F_BAR. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiC9JLA8_HUMAN
AccessioniPrimary (citable) accession number: C9JLA8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 10, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.