Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Exportin-1

Gene

XPO1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Exportin-1Imported
Gene namesi
Name:XPO1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000082898.16.
HGNCiHGNC:12825. XPO1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000082898.

PTM / Processingi

Proteomic databases

MaxQBiC9JKM9.
PaxDbiC9JKM9.
PeptideAtlasiC9JKM9.
PRIDEiC9JKM9.

Expressioni

Gene expression databases

BgeeiENSG00000082898.
ExpressionAtlasiC9JKM9. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliC9JKM9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 112Importin N-terminalInterPro annotationAdd BLAST67

Phylogenomic databases

eggNOGiKOG2020. Eukaryota.
COG5101. LUCA.
GeneTreeiENSGT00390000000572.
HOGENOMiHOG000177811.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiView protein in InterPro
IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR013598. Exportin-1/Importin-b-like.
IPR001494. Importin-beta_N.
PfamiView protein in Pfam
PF03810. IBN_N. 1 hit.
PF08389. Xpo1. 1 hit.
SMARTiView protein in SMART
SM00913. IBN_N. 1 hit.
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiView protein in PROSITE
PS50166. IMPORTIN_B_NT. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9JKM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAIMTMLAD HAARQLLDFS QKLDINLLDN VVNCLYHGEG AQQRMAQEVL
60 70 80 90 100
THLKEHPDAW TRVDTILEFS QNMNTKYYGL QILENVIKTR WKILPRNQCE
110 120 130 140 150
GIKKYVVGLI IKTSSDPTCV EKEKVYIGKL NMILVQILKQ EWPKHWPTFI
160 170
SDIVGASRTS ESLCQNNMVI LKLLSEEVF
Length:179
Mass (Da):20,644
Last modified:November 3, 2009 - v1
Checksum:i8ABB42F92913B866
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei179Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016727 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000451765; ENSP00000413853; ENSG00000082898.
UCSCiuc061jol.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9JKM9_HUMAN
AccessioniPrimary (citable) accession number: C9JKM9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 27, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported