ID   C9JK31_HUMAN            Unreviewed;        98 AA.
AC   C9JK31;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   SubName: Full=Zinc finger protein 3 {ECO:0000313|Ensembl:ENSP00000394113.1};
DE   Flags: Fragment;
GN   Name=ZNF3 {ECO:0000313|Ensembl:ENSP00000394113.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000394113.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000394113.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA   Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA   Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA   Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA   Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA   Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA   Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA   Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA   Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA   Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA   Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA   Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA   Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA   Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA   Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA   McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA   Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0007829|PubMed:28112733}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=28112733;
RA   Hendriks I.A., Lyon D., Young C., Jensen L.J., Vertegaal A.C.,
RA   Nielsen M.L.;
RT   "Site-specific mapping of the human SUMO proteome reveals co-modification
RT   with phosphorylation.";
RL   Nat. Struct. Mol. Biol. 24:325-336(2017).
RN   [3] {ECO:0000313|Ensembl:ENSP00000394113.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC073842; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC093619; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; C9JK31; -.
DR   SMR; C9JK31; -.
DR   MassIVE; C9JK31; -.
DR   MaxQB; C9JK31; -.
DR   PeptideAtlas; C9JK31; -.
DR   ProteomicsDB; 10531; -.
DR   Antibodypedia; 832; 140 antibodies from 22 providers.
DR   Ensembl; ENST00000441298.5; ENSP00000394113.1; ENSG00000166526.19.
DR   UCSC; uc064fyj.1; human.
DR   HGNC; HGNC:13089; ZNF3.
DR   VEuPathDB; HostDB:ENSG00000166526; -.
DR   GeneTree; ENSGT00940000153104; -.
DR   HOGENOM; CLU_002678_69_5_1; -.
DR   OMA; MGDRPHK; -.
DR   ChiTaRS; ZNF3; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000166526; Expressed in right uterine tube and 172 other cell types or tissues.
DR   ExpressionAtlas; C9JK31; baseline and differential.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd07765; KRAB_A-box; 1.
DR   Gene3D; 6.10.140.140; -; 1.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036051; KRAB_dom_sf.
DR   PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR   PANTHER; PTHR23232:SF143; ZINC FINGER PROTEIN 747; 1.
DR   Pfam; PF01352; KRAB; 1.
DR   SMART; SM00349; KRAB; 1.
DR   SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR   PROSITE; PS50805; KRAB; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:C9JK31,
KW   ECO:0007829|MaxQB:C9JK31};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          15..98
FT                   /note="KRAB"
FT                   /evidence="ECO:0000259|PROSITE:PS50805"
FT   NON_TER         98
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000394113.1"
SQ   SEQUENCE   98 AA;  11574 MW;  B1BA2AC5AC05E376 CRC64;
     MLAAALLKAK SQELVTFEDV AVYFIRKEWK RLEPAQRDLY RDVMLENYGN VFSLDRETRT
     ENDQEISEDT RSHGVLLGRF QKDISQGLKF KEAYEREV
//