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Protein
Submitted name:

Isocitrate dehydrogenase [NADP] cytoplasmic

Gene

IDH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase [NADP] cytoplasmicImported
Gene namesi
Name:IDH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:5382. IDH1.

PTM / Processingi

Proteomic databases

PaxDbiC9JJE5.
PeptideAtlasiC9JJE5.
PRIDEiC9JJE5.

Expressioni

Gene expression databases

BgeeiENSG00000138413.
ExpressionAtlasiC9JJE5. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000260985.

Structurei

3D structure databases

ProteinModelPortaliC9JJE5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 6151Iso_dhInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1526. Eukaryota.
COG0538. LUCA.
GeneTreeiENSGT00390000012547.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR004790. Isocitrate_DH_NADP.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11822. PTHR11822. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C9JJE5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKKISGGSV VEMQGDEMTR IIWELIKEKL IFPYVELDLH SYDLGIENRD
60
ATNDQVTKDA AE
Length:62
Mass (Da):7,072
Last modified:November 3, 2009 - v1
Checksum:iC9EFB9CD62A86991
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei62 – 621Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016697 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000451391; ENSP00000396787; ENSG00000138413.
UCSCiuc061rww.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016697 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliC9JJE5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000260985.

Proteomic databases

PaxDbiC9JJE5.
PeptideAtlasiC9JJE5.
PRIDEiC9JJE5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000451391; ENSP00000396787; ENSG00000138413.
UCSCiuc061rww.1. human.

Organism-specific databases

HGNCiHGNC:5382. IDH1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1526. Eukaryota.
COG0538. LUCA.
GeneTreeiENSGT00390000012547.

Miscellaneous databases

ChiTaRSiIDH1. human.

Gene expression databases

BgeeiENSG00000138413.
ExpressionAtlasiC9JJE5. baseline and differential.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR004790. Isocitrate_DH_NADP.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11822. PTHR11822. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC9JJE5_HUMAN
AccessioniPrimary (citable) accession number: C9JJE5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 7, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.