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C9JIZ6

- C9JIZ6_HUMAN

UniProt

C9JIZ6 - C9JIZ6_HUMAN

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Protein
Submitted name: Prosaposin
Gene
PSAP
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. sphingolipid metabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ProsaposinImported
Gene namesi
Name:PSAPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 10

Organism-specific databases

HGNCiHGNC:9498. PSAP.

Subcellular locationi

GO - Cellular componenti

  1. lysosome Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Proteomic databases

PRIDEiC9JIZ6.

Expressioni

Gene expression databases

ArrayExpressiC9JIZ6.
BgeeiC9JIZ6.

Structurei

3D structure databases

ProteinModelPortaliC9JIZ6.
SMRiC9JIZ6. Positions 60-139, 195-274, 314-486.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000049216.
OMAiCKNYINQ.

Family and domain databases

Gene3Di1.10.225.10. 4 hits.
InterProiIPR003119. SapA.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR021165. Saposin_chordata.
IPR008139. SaposinB.
[Graphical view]
PfamiPF02199. SapA. 2 hits.
PF05184. SapB_1. 4 hits.
PF03489. SapB_2. 4 hits.
[Graphical view]
PIRSFiPIRSF002431. Saposin. 1 hit.
PRINTSiPR01797. SAPOSIN.
SMARTiSM00162. SAPA. 2 hits.
SM00741. SapB. 4 hits.
[Graphical view]
SUPFAMiSSF47862. SSF47862. 4 hits.
PROSITEiPS51110. SAP_A. 2 hits.
PS50015. SAP_B. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9JIZ6-1 [UniParc]FASTAAdd to Basket

« Hide

MYALFLLASL LGAALAGPVL GLKECTRGSA VWCQNVKTAS DCGAVKHCLQ    50
TVWNKPTVKS LPCDICKDVV TAAGDMLKDN ATEEEILVYL EKTCDWLPKP 100
NMSASCKEIV DSYLPVILDI IKGEMSRPGE VCSALNLCES LQKHLAELNH 150
QKQLESNKIP ELDMTEVVAP FMANIPLLLY PQDGPRSKPQ PKDNGDVCQD 200
CIQMVTDIQT AVRTNSTFVQ ALVEHVKEEC DRLGPGMADI CKNYISQYSE 250
IAIQMMMHML QQPKEICALV GFCDEVKEMP MQTLVPAKVA SKNVIPALEL 300
VEPIKKHEVP AKSDVYCEVC EFLVKEVTKL IDNNKTEKEI LDAFDKMCSK 350
LPKSLSEECQ EVVDTYGSSI LSILLEEVSP ELVCSMLHLC SGTRLPALTV 400
HVTQPKDGGF CEVCKKLVGY LDRNLEKNST KQEILAALEK GCSFLPDPYQ 450
KQCDQFVAEY EPVLIEILVE VMDPSFVCLK IGACPSAHKP LLGTEKCIWG 500
PSYWCQNTET AAQCNAVEHC KRHVWN 526
Length:526
Mass (Da):58,354
Last modified:November 3, 2009 - v1
Checksum:iF26E56CAC3A9DCE7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC073370 Genomic DNA. No translation available.
AL731541 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000394934; ENSP00000378392; ENSG00000197746.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC073370 Genomic DNA. No translation available.
AL731541 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali C9JIZ6.
SMRi C9JIZ6. Positions 60-139, 195-274, 314-486.
ModBasei Search...

Proteomic databases

PRIDEi C9JIZ6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000394934 ; ENSP00000378392 ; ENSG00000197746 .

Organism-specific databases

HGNCi HGNC:9498. PSAP.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000049216.
OMAi CKNYINQ.

Miscellaneous databases

ChiTaRSi PSAP. human.
NextBioi 35486688.

Gene expression databases

ArrayExpressi C9JIZ6.
Bgeei C9JIZ6.

Family and domain databases

Gene3Di 1.10.225.10. 4 hits.
InterProi IPR003119. SapA.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR021165. Saposin_chordata.
IPR008139. SaposinB.
[Graphical view ]
Pfami PF02199. SapA. 2 hits.
PF05184. SapB_1. 4 hits.
PF03489. SapB_2. 4 hits.
[Graphical view ]
PIRSFi PIRSF002431. Saposin. 1 hit.
PRINTSi PR01797. SAPOSIN.
SMARTi SM00162. SAPA. 2 hits.
SM00741. SapB. 4 hits.
[Graphical view ]
SUPFAMi SSF47862. SSF47862. 4 hits.
PROSITEi PS51110. SAP_A. 2 hits.
PS50015. SAP_B. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9JIZ6_HUMAN
AccessioniPrimary (citable) accession number: C9JIZ6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: June 11, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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