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C9JIZ6

- C9JIZ6_HUMAN

UniProt

C9JIZ6 - C9JIZ6_HUMAN

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Protein
Submitted name:

Prosaposin

Gene

PSAP

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. sphingolipid metabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ProsaposinImported
Gene namesi
Name:PSAPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 10

Organism-specific databases

HGNCiHGNC:9498. PSAP.

Subcellular locationi

GO - Cellular componenti

  1. lysosome Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PRIDEiC9JIZ6.

Expressioni

Gene expression databases

BgeeiC9JIZ6.
ExpressionAtlasiC9JIZ6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JIZ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063434.
HOGENOMiHOG000049216.
OMAiCKNYINQ.

Family and domain databases

Gene3Di1.10.225.10. 4 hits.
InterProiIPR003119. SapA.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR021165. Saposin_chordata.
IPR008139. SaposinB.
[Graphical view]
PfamiPF02199. SapA. 2 hits.
PF05184. SapB_1. 4 hits.
PF03489. SapB_2. 4 hits.
[Graphical view]
PIRSFiPIRSF002431. Saposin. 1 hit.
PRINTSiPR01797. SAPOSIN.
SMARTiSM00162. SAPA. 2 hits.
SM00741. SapB. 4 hits.
[Graphical view]
SUPFAMiSSF47862. SSF47862. 4 hits.
PROSITEiPS51110. SAP_A. 2 hits.
PS50015. SAP_B. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9JIZ6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYALFLLASL LGAALAGPVL GLKECTRGSA VWCQNVKTAS DCGAVKHCLQ
60 70 80 90 100
TVWNKPTVKS LPCDICKDVV TAAGDMLKDN ATEEEILVYL EKTCDWLPKP
110 120 130 140 150
NMSASCKEIV DSYLPVILDI IKGEMSRPGE VCSALNLCES LQKHLAELNH
160 170 180 190 200
QKQLESNKIP ELDMTEVVAP FMANIPLLLY PQDGPRSKPQ PKDNGDVCQD
210 220 230 240 250
CIQMVTDIQT AVRTNSTFVQ ALVEHVKEEC DRLGPGMADI CKNYISQYSE
260 270 280 290 300
IAIQMMMHMS LQQPKEICAL VGFCDEVKEM PMQTLVPAKV ASKNVIPALE
310 320 330 340 350
LVEPIKKHEV PAKSDVYCEV CEFLVKEVTK LIDNNKTEKE ILDAFDKMCS
360 370 380 390 400
KLPKSLSEEC QEVVDTYGSS ILSILLEEVS PELVCSMLHL CSGTRLPALT
410 420 430 440 450
VHVTQPKDGG FCEVCKKLVG YLDRNLEKNS TKQEILAALE KGCSFLPDPY
460 470 480 490 500
QKQCDQFVAE YEPVLIEILV EVMDPSFVCL KIGACPSAHK PLLGTEKCIW
510 520
GPSYWCQNTE TAAQCNAVEH CKRHVWN
Length:527
Mass (Da):58,441
Last modified:October 29, 2014 - v2
Checksum:iD7FDB9DC50FA2F22
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073370 Genomic DNA. No translation available.
AL731541 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000394934; ENSP00000378392; ENSG00000197746.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073370 Genomic DNA. No translation available.
AL731541 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali C9JIZ6.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi C9JIZ6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000394934 ; ENSP00000378392 ; ENSG00000197746 .

Organism-specific databases

HGNCi HGNC:9498. PSAP.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00530000063434.
HOGENOMi HOG000049216.
OMAi CKNYINQ.

Miscellaneous databases

ChiTaRSi PSAP. human.
NextBioi 35486688.

Gene expression databases

Bgeei C9JIZ6.
ExpressionAtlasi C9JIZ6. baseline and differential.

Family and domain databases

Gene3Di 1.10.225.10. 4 hits.
InterProi IPR003119. SapA.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR021165. Saposin_chordata.
IPR008139. SaposinB.
[Graphical view ]
Pfami PF02199. SapA. 2 hits.
PF05184. SapB_1. 4 hits.
PF03489. SapB_2. 4 hits.
[Graphical view ]
PIRSFi PIRSF002431. Saposin. 1 hit.
PRINTSi PR01797. SAPOSIN.
SMARTi SM00162. SAPA. 2 hits.
SM00741. SapB. 4 hits.
[Graphical view ]
SUPFAMi SSF47862. SSF47862. 4 hits.
PROSITEi PS51110. SAP_A. 2 hits.
PS50015. SAP_B. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9JIZ6_HUMAN
AccessioniPrimary (citable) accession number: C9JIZ6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 29, 2014
Last modified: November 26, 2014
This is version 40 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3