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C9JI98

- TM238_HUMAN

UniProt

C9JI98 - TM238_HUMAN

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Protein

Transmembrane protein 238

Gene

TMEM238

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 238
Gene namesi
Name:TMEM238
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:40042. TMEM238.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3636CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei37 – 5721HelicalSequence AnalysisAdd
BLAST
Topological domaini58 – 6912ExtracellularSequence AnalysisAdd
BLAST
Transmembranei70 – 9021HelicalSequence AnalysisAdd
BLAST
Topological domaini91 – 17686CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 176176Transmembrane protein 238PRO_0000413540Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei175 – 1751Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiC9JI98.
PaxDbiC9JI98.
PRIDEiC9JI98.

PTM databases

PhosphoSiteiC9JI98.

Expressioni

Gene expression databases

BgeeiC9JI98.

Structurei

3D structure databases

ProteinModelPortaliC9JI98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi2 – 5150Ala-richAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG78806.
GeneTreeiENSGT00390000013421.
HOGENOMiHOG000169144.
InParanoidiC9JI98.
OMAiFRIPNIR.
OrthoDBiEOG77HDHK.
PhylomeDBiC9JI98.
TreeFamiTF339060.

Family and domain databases

InterProiIPR029365. TMEM238.
[Graphical view]
PfamiPF15125. TMEM238. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9JI98-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAAAPAVCAS QGSPPGAPSA PAAAPAPAAG LGRCRMALLL AVALDVAGMA
60 70 80 90 100
ALLTGVFAQL QVRGRDFGDL LIYSGALLVF LSLLGWILWY TGNIEISRQE
110 120 130 140 150
LERDYGLRPS ALARLARKLS RRWSAPAAAG QRPAPGSRRA RRAARAPPPP
160 170
AAGSRRVRLQ LATLEAGPGA AGAGSE
Length:176
Mass (Da):18,040
Last modified:November 3, 2009 - v1
Checksum:i323ABC220EC3506C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti14 – 141P → S in BC052596. (PubMed:15489334)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020922 Genomic DNA. No translation available.
BC052596 mRNA. No translation available.
CCDSiCCDS54323.1.
RefSeqiNP_001177693.1. NM_001190764.1.
UniGeneiHs.534672.

Genome annotation databases

EnsembliENST00000444469; ENSP00000416154; ENSG00000233493.
GeneIDi388564.
KEGGihsa:388564.
UCSCiuc002qku.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020922 Genomic DNA. No translation available.
BC052596 mRNA. No translation available.
CCDSi CCDS54323.1.
RefSeqi NP_001177693.1. NM_001190764.1.
UniGenei Hs.534672.

3D structure databases

ProteinModelPortali C9JI98.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei C9JI98.

Proteomic databases

MaxQBi C9JI98.
PaxDbi C9JI98.
PRIDEi C9JI98.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000444469 ; ENSP00000416154 ; ENSG00000233493 .
GeneIDi 388564.
KEGGi hsa:388564.
UCSCi uc002qku.3. human.

Organism-specific databases

CTDi 388564.
GeneCardsi GC19M055891.
HGNCi HGNC:40042. TMEM238.
neXtProti NX_C9JI98.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG78806.
GeneTreei ENSGT00390000013421.
HOGENOMi HOG000169144.
InParanoidi C9JI98.
OMAi FRIPNIR.
OrthoDBi EOG77HDHK.
PhylomeDBi C9JI98.
TreeFami TF339060.

Miscellaneous databases

NextBioi 102163.
PROi C9JI98.

Gene expression databases

Bgeei C9JI98.

Family and domain databases

InterProi IPR029365. TMEM238.
[Graphical view ]
Pfami PF15125. TMEM238. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and biology of human chromosome 19."
    Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
    , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
    Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 9-176.
    Tissue: Mammary carcinoma.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-175, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.

Entry informationi

Entry nameiTM238_HUMAN
AccessioniPrimary (citable) accession number: C9JI98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: November 3, 2009
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM

External Data

Dasty 3