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Protein
Submitted name:

Protein-tyrosine kinase 2-beta

Gene

PTK2B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein-tyrosine kinase 2-betaImported
Gene namesi
Name:PTK2BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:9612. PTK2B.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiC9JHV9.
PeptideAtlasiC9JHV9.
PRIDEiC9JHV9.

Expressioni

Gene expression databases

BgeeiENSG00000120899.
ExpressionAtlasiC9JHV9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000332816.

Structurei

3D structure databases

ProteinModelPortaliC9JHV9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 213175FERMInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG4257. Eukaryota.
ENOG410ZH9Y. LUCA.
GeneTreeiENSGT00760000118799.
HOGENOMiHOG000069938.

Family and domain databases

InterProiIPR019749. Band_41_domain.
IPR019748. FERM_central.
IPR000299. FERM_domain.
IPR030610. PTK2B.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR24418:SF94. PTHR24418:SF94. 1 hit.
SMARTiSM00295. B41. 1 hit.
[Graphical view]
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50057. FERM_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C9JHV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGVSEPLSR VKLGTLRRPE GPAEPMVVVP VDVEKEDVRI LKVCFYSNSF
60 70 80 90 100
NPGKNFKLVK CTVQTEIREI ITSILLSGRI GPNIRLAECY GLRLKHMKSD
110 120 130 140 150
EIHWLHPQMT VGEVQDKYEC LHVEAEWRYD LQIRYLPEDF MESLKEDRTT
160 170 180 190 200
LLYFYQQLRN DYMQRYASKV SEGMALQLGC LELRRFFKDM PHNALDKKSN
210
FELLEKEVGL DLF
Length:213
Mass (Da):24,939
Last modified:November 3, 2009 - v1
Checksum:i526F311C9D0EBC25
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei213 – 2131Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010856 Genomic DNA. No translation available.
AC124649 Genomic DNA. No translation available.
AF311103 Genomic DNA. No translation available.
KC877228 Genomic DNA. No translation available.
KF458717 Genomic DNA. No translation available.
KF458718 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000412793; ENSP00000416174; ENSG00000120899.
UCSCiuc064lkp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010856 Genomic DNA. No translation available.
AC124649 Genomic DNA. No translation available.
AF311103 Genomic DNA. No translation available.
KC877228 Genomic DNA. No translation available.
KF458717 Genomic DNA. No translation available.
KF458718 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliC9JHV9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000332816.

Proteomic databases

PaxDbiC9JHV9.
PeptideAtlasiC9JHV9.
PRIDEiC9JHV9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000412793; ENSP00000416174; ENSG00000120899.
UCSCiuc064lkp.1. human.

Organism-specific databases

HGNCiHGNC:9612. PTK2B.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4257. Eukaryota.
ENOG410ZH9Y. LUCA.
GeneTreeiENSGT00760000118799.
HOGENOMiHOG000069938.

Miscellaneous databases

ChiTaRSiPTK2B. human.

Gene expression databases

BgeeiENSG00000120899.
ExpressionAtlasiC9JHV9. baseline and differential.

Family and domain databases

InterProiIPR019749. Band_41_domain.
IPR019748. FERM_central.
IPR000299. FERM_domain.
IPR030610. PTK2B.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR24418:SF94. PTHR24418:SF94. 1 hit.
SMARTiSM00295. B41. 1 hit.
[Graphical view]
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50057. FERM_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC9JHV9_HUMAN
AccessioniPrimary (citable) accession number: C9JHV9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 7, 2016
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.