Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Scavenger receptor cysteine-rich type 1 protein M130

Gene

CD163

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Scavenger receptor cysteine-rich type 1 protein M130Imported
Gene namesi
Name:CD163Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi

Organism-specific databases

EuPathDBiHostDB:ENSG00000177575.12
HGNCiHGNC:1631 CD163

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 44HelicalSequence analysisAdd BLAST24
Transmembranei1084 – 1104HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000177575

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi120 ↔ 130PROSITE-ProRule annotation
Disulfide bondi184 ↔ 248PROSITE-ProRule annotation
Disulfide bondi197 ↔ 258PROSITE-ProRule annotation
Disulfide bondi228 ↔ 238PROSITE-ProRule annotation
Disulfide bondi291 ↔ 355PROSITE-ProRule annotation
Disulfide bondi304 ↔ 365PROSITE-ProRule annotation
Disulfide bondi335 ↔ 345PROSITE-ProRule annotation
Disulfide bondi398 ↔ 462PROSITE-ProRule annotation
Disulfide bondi411 ↔ 472PROSITE-ProRule annotation
Disulfide bondi442 ↔ 452PROSITE-ProRule annotation
Disulfide bondi503 ↔ 567PROSITE-ProRule annotation
Disulfide bondi516 ↔ 577PROSITE-ProRule annotation
Disulfide bondi547 ↔ 557PROSITE-ProRule annotation
Disulfide bondi641 ↔ 705PROSITE-ProRule annotation
Disulfide bondi654 ↔ 715PROSITE-ProRule annotation
Disulfide bondi685 ↔ 695PROSITE-ProRule annotation
Disulfide bondi777 ↔ 841PROSITE-ProRule annotation
Disulfide bondi790 ↔ 851PROSITE-ProRule annotation
Disulfide bondi821 ↔ 831PROSITE-ProRule annotation
Disulfide bondi884 ↔ 948PROSITE-ProRule annotation
Disulfide bondi897 ↔ 958PROSITE-ProRule annotation
Disulfide bondi928 ↔ 938PROSITE-ProRule annotation
Disulfide bondi987 ↔ 1051PROSITE-ProRule annotation
Disulfide bondi1000 ↔ 1061PROSITE-ProRule annotation
Disulfide bondi1031 ↔ 1041PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PeptideAtlasiC9JHR8
PRIDEiC9JHR8

Expressioni

Gene expression databases

BgeeiENSG00000177575
ExpressionAtlasiC9JHR8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JHR8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 152SRCRInterPro annotationAdd BLAST102
Domaini159 – 259SRCRInterPro annotationAdd BLAST101
Domaini266 – 366SRCRInterPro annotationAdd BLAST101
Domaini373 – 473SRCRInterPro annotationAdd BLAST101
Domaini478 – 578SRCRInterPro annotationAdd BLAST101
Domaini616 – 716SRCRInterPro annotationAdd BLAST101
Domaini752 – 852SRCRInterPro annotationAdd BLAST101
Domaini857 – 959SRCRInterPro annotationAdd BLAST103
Domaini962 – 1062SRCRInterPro annotationAdd BLAST101

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHBC Eukaryota
ENOG410XQVR LUCA
GeneTreeiENSGT00900000140803
HOGENOMiHOG000290652

Family and domain databases

Gene3Di3.10.250.10, 9 hits
InterProiView protein in InterPro
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
PfamiView protein in Pfam
PF00530 SRCR, 9 hits
PRINTSiPR00258 SPERACTRCPTR
SMARTiView protein in SMART
SM00202 SR, 9 hits
SUPFAMiSSF56487 SSF56487, 9 hits
PROSITEiView protein in PROSITE
PS00420 SRCR_1, 4 hits
PS50287 SRCR_2, 9 hits

Sequencei

Sequence statusi: Complete.

C9JHR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKLRMVLLE DSGSADFRRH FVNLSPFTIT VVLLLSACFV TSSLGGTDKE
60 70 80 90 100
LRLVDGENKC SGRVEVKVQE EWGTVCNNGW SMEAVSVICN QLGCPTAIKA
110 120 130 140 150
PGWANSSAGS GRIWMDHVSC RGNESALWDC KHDGWGKHSN CTHQQDAGVT
160 170 180 190 200
CSDGSNLEMR LTRGGNMCSG RIEIKFQGRW GTVCDDNFNI DHASVICRQL
210 220 230 240 250
ECGSAVSFSG SSNFGEGSGP IWFDDLICNG NESALWNCKH QGWGKHNCDH
260 270 280 290 300
AEDAGVICSK GADLSLRLVD GVTECSGRLE VRFQGEWGTI CDDGWDSYDA
310 320 330 340 350
AVACKQLGCP TAVTAIGRVN ASKGFGHIWL DSVSCQGHEP AIWQCKHHEW
360 370 380 390 400
GKHYCNHNED AGVTCSDGSD LELRLRGGGS RCAGTVEVEI QRLLGKVCDR
410 420 430 440 450
GWGLKEADVV CRQLGCGSAL KTSYQVYSKI QATNTWLFLS SCNGNETSLW
460 470 480 490 500
DCKNWQWGGL TCDHYEEAKI TCSAHREPRL VGGDIPCSGR VEVKHGDTWG
510 520 530 540 550
SICDSDFSLE AASVLCRELQ CGTVVSILGG AHFGEGNGQI WAEEFQCEGH
560 570 580 590 600
ESHLSLCPVA PRPEGTCSHS RDVGVVCSSK TQKTSLIGSH TVKGTGLGSH
610 620 630 640 650
SCLFLKPCLL PGYTEIRLVN GKTPCEGRVE LKTLGAWGSL CNSHWDIEDA
660 670 680 690 700
HVLCQQLKCG VALSTPGGAR FGKGNGQIWR HMFHCTGTEQ HMGDCPVTAL
710 720 730 740 750
GASLCPSEQV ASVICSGNQS QTLSSCNSSS LGPTRPTIPE ESAVACIESG
760 770 780 790 800
QLRLVNGGGR CAGRVEIYHE GSWGTICDDS WDLSDAHVVC RQLGCGEAIN
810 820 830 840 850
ATGSAHFGEG TGPIWLDEMK CNGKESRIWQ CHSHGWGQQN CRHKEDAGVI
860 870 880 890 900
CSEFMSLRLT SEASREACAG RLEVFYNGAW GTVGKSSMSE TTVGVVCRQL
910 920 930 940 950
GCADKGKINP ASLDKAMSIP MWVDNVQCPK GPDTLWQCPS SPWEKRLASP
960 970 980 990 1000
SEETWITCDN KIRLQEGPTS CSGRVEIWHG GSWGTVCDDS WDLDDAQVVC
1010 1020 1030 1040 1050
QQLGCGPALK AFKEAEFGQG TGPIWLNEVK CKGNESSLWD CPARRWGHSE
1060 1070 1080 1090 1100
CGHKEDAAVN CTDISVQKTP QKATTGRSSR QSSFIAVGIL GVVLLAIFVA
1110 1120 1130 1140 1150
LFFLTKKRRQ RQRLAVSSRG ENLVHQIQYR EMNSCLNADD LDLMNSSGGH

SEPH
Length:1,154
Mass (Da):124,932
Last modified:November 3, 2009 - v1
Checksum:i92A8915FB7279AB8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC131206 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000396620; ENSP00000379863; ENSG00000177575
UCSCiuc009zfw.3 human

Entry informationi

Entry nameiC9JHR8_HUMAN
AccessioniPrimary (citable) accession number: C9JHR8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: March 28, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health