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C9JHR8

- C9JHR8_HUMAN

UniProt

C9JHR8 - C9JHR8_HUMAN

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Protein
Submitted name: Scavenger receptor cysteine-rich type 1 protein M130
Gene
CD163
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. scavenger receptor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Scavenger receptor cysteine-rich type 1 protein M130Imported
    Gene namesi
    Name:CD163Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:1631. CD163.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro
    Complete GO annotation...

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotations

    Proteomic databases

    PRIDEiC9JHR8.

    Expressioni

    Gene expression databases

    ArrayExpressiC9JHR8.
    BgeeiC9JHR8.

    Structurei

    3D structure databases

    ProteinModelPortaliC9JHR8.
    SMRiC9JHR8. Positions 48-264, 277-366, 373-473, 479-581, 615-716, 747-857, 870-1063.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000290652.
    KOiK06545.

    Family and domain databases

    Gene3Di3.10.250.10. 9 hits.
    InterProiIPR001190. SRCR.
    IPR017448. SRCR-like_dom.
    [Graphical view]
    PfamiPF00530. SRCR. 9 hits.
    [Graphical view]
    PRINTSiPR00258. SPERACTRCPTR.
    SMARTiSM00202. SR. 9 hits.
    [Graphical view]
    SUPFAMiSSF56487. SSF56487. 9 hits.
    PROSITEiPS00420. SRCR_1. 4 hits.
    PS50287. SRCR_2. 9 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C9JHR8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKLRMVLLE DSGSADFRRH FVNLSPFTIT VVLLLSACFV TSSLGGTDKE     50
    LRLVDGENKC SGRVEVKVQE EWGTVCNNGW SMEAVSVICN QLGCPTAIKA 100
    PGWANSSAGS GRIWMDHVSC RGNESALWDC KHDGWGKHSN CTHQQDAGVT 150
    CSDGSNLEMR LTRGGNMCSG RIEIKFQGRW GTVCDDNFNI DHASVICRQL 200
    ECGSAVSFSG SSNFGEGSGP IWFDDLICNG NESALWNCKH QGWGKHNCDH 250
    AEDAGVICSK GADLSLRLVD GVTECSGRLE VRFQGEWGTI CDDGWDSYDA 300
    AVACKQLGCP TAVTAIGRVN ASKGFGHIWL DSVSCQGHEP AIWQCKHHEW 350
    GKHYCNHNED AGVTCSDGSD LELRLRGGGS RCAGTVEVEI QRLLGKVCDR 400
    GWGLKEADVV CRQLGCGSAL KTSYQVYSKI QATNTWLFLS SCNGNETSLW 450
    DCKNWQWGGL TCDHYEEAKI TCSAHREPRL VGGDIPCSGR VEVKHGDTWG 500
    SICDSDFSLE AASVLCRELQ CGTVVSILGG AHFGEGNGQI WAEEFQCEGH 550
    ESHLSLCPVA PRPEGTCSHS RDVGVVCSSK TQKTSLIGSH TVKGTGLGSH 600
    SCLFLKPCLL PGYTEIRLVN GKTPCEGRVE LKTLGAWGSL CNSHWDIEDA 650
    HVLCQQLKCG VALSTPGGAR FGKGNGQIWR HMFHCTGTEQ HMGDCPVTAL 700
    GASLCPSEQV ASVICSGNQS QTLSSCNSSS LGPTRPTIPE ESAVACIESG 750
    QLRLVNGGGR CAGRVEIYHE GSWGTICDDS WDLSDAHVVC RQLGCGEAIN 800
    ATGSAHFGEG TGPIWLDEMK CNGKESRIWQ CHSHGWGQQN CRHKEDAGVI 850
    CSEFMSLRLT SEASREACAG RLEVFYNGAW GTVGKSSMSE TTVGVVCRQL 900
    GCADKGKINP ASLDKAMSIP MWVDNVQCPK GPDTLWQCPS SPWEKRLASP 950
    SEETWITCDN KIRLQEGPTS CSGRVEIWHG GSWGTVCDDS WDLDDAQVVC 1000
    QQLGCGPALK AFKEAEFGQG TGPIWLNEVK CKGNESSLWD CPARRWGHSE 1050
    CGHKEDAAVN CTDISVQKTP QKATTGRSSR QSSFIAVGIL GVVLLAIFVA 1100
    LFFLTKKRRQ RQRLAVSSRG ENLVHQIQYR EMNSCLNADD LDLMNSSGGH 1150
    SEPH 1154
    Length:1,154
    Mass (Da):124,932
    Last modified:November 3, 2009 - v1
    Checksum:i92A8915FB7279AB8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC131206 Genomic DNA. No translation available.
    RefSeqiXP_005253585.1. XM_005253528.2.
    UniGeneiHs.504641.

    Genome annotation databases

    EnsembliENST00000396620; ENSP00000379863; ENSG00000177575.
    GeneIDi9332.
    KEGGihsa:9332.
    UCSCiuc009zfw.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC131206 Genomic DNA. No translation available.
    RefSeqi XP_005253585.1. XM_005253528.2.
    UniGenei Hs.504641.

    3D structure databases

    ProteinModelPortali C9JHR8.
    SMRi C9JHR8. Positions 48-264, 277-366, 373-473, 479-581, 615-716, 747-857, 870-1063.
    ModBasei Search...

    Proteomic databases

    PRIDEi C9JHR8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000396620 ; ENSP00000379863 ; ENSG00000177575 .
    GeneIDi 9332.
    KEGGi hsa:9332.
    UCSCi uc009zfw.2. human.

    Organism-specific databases

    CTDi 9332.
    HGNCi HGNC:1631. CD163.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000290652.
    KOi K06545.

    Miscellaneous databases

    ChiTaRSi CD163. human.
    GenomeRNAii 9332.
    NextBioi 35486540.

    Gene expression databases

    ArrayExpressi C9JHR8.
    Bgeei C9JHR8.

    Family and domain databases

    Gene3Di 3.10.250.10. 9 hits.
    InterProi IPR001190. SRCR.
    IPR017448. SRCR-like_dom.
    [Graphical view ]
    Pfami PF00530. SRCR. 9 hits.
    [Graphical view ]
    PRINTSi PR00258. SPERACTRCPTR.
    SMARTi SM00202. SR. 9 hits.
    [Graphical view ]
    SUPFAMi SSF56487. SSF56487. 9 hits.
    PROSITEi PS00420. SRCR_1. 4 hits.
    PS50287. SRCR_2. 9 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "The finished DNA sequence of human chromosome 12."
      Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9JHR8_HUMAN
    AccessioniPrimary (citable) accession number: C9JHR8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: July 9, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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