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Protein
Submitted name:

C-X-C chemokine receptor type 2

Gene

CXCR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
C-X-C chemokine receptor type 2Imported
Gene namesi
Name:CXCR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000180871.7.
HGNCiHGNC:6027. CXCR2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei49 – 74HelicalSequence analysisAdd BLAST26
Transmembranei86 – 105HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000180871.

Expressioni

Gene expression databases

BgeeiENSG00000180871.
ExpressionAtlasiC9JG19. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliC9JG19.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 135G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST71

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEHI. Eukaryota.
ENOG410Y9Y6. LUCA.
GeneTreeiENSGT00760000118785.

Family and domain databases

InterProiView protein in InterPro
IPR000057. Chemokine_CXCR2.
IPR000174. Chemokine_CXCR_1/2.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00427. INTRLEUKIN8R.
PR00573. INTRLEUKN8BR.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9JG19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDFNMESDS FEDFWKGEDL SNYSYSSTLP PFLLDAAPCE PESLEINKYF
60 70 80 90 100
VVIIYALVFL LSLLGNSLVM LVILYSRVGR SVTDVYLLNL ALADLLFALT
110 120 130
LPIWAASKVN GWIFGTFLCK VVSLLKEVNF YSGIL
Length:135
Mass (Da):15,212
Last modified:October 5, 2016 - v8
Checksum:iF4BD116B2A52F56F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei135Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124768 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000454148; ENSP00000415148; ENSG00000180871.
UCSCiuc061sib.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9JG19_HUMAN
AccessioniPrimary (citable) accession number: C9JG19
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: January 31, 2018
This is version 58 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported