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Protein
Submitted name:

Synaptojanin-1

Gene

SYNJ1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Synaptojanin-1Imported
Gene namesi
Name:SYNJ1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 21

Organism-specific databases

HGNCiHGNC:11503. SYNJ1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000159082.
PharmGKBiPA36285.

PTM / Processingi

Proteomic databases

MaxQBiC9JFZ1.
PaxDbiC9JFZ1.
PRIDEiC9JFZ1.

Expressioni

Gene expression databases

BgeeiENSG00000159082.
ExpressionAtlasiC9JFZ1. baseline and differential.
GenevisibleiC9JFZ1. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000409667.

Structurei

3D structure databases

ProteinModelPortaliC9JFZ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 481SACInterPro annotationAdd BLAST324
Domaini941 – 1010RRM (RNA recognition motif)InterPro annotationAdd BLAST70

Phylogenomic databases

eggNOGiKOG0566. Eukaryota.
COG5329. LUCA.
COG5411. LUCA.
GeneTreeiENSGT00760000119075.
HOGENOMiHOG000007937.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
3.60.10.10. 1 hit.
InterProiIPR015047. DUF1866.
IPR005135. Endo/exonuclease/phosphatase.
IPR000300. IPPc.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR002013. SAC_dom.
[Graphical view]
PfamiPF08952. DUF1866. 1 hit.
PF03372. Exo_endo_phos. 1 hit.
PF02383. Syja_N. 1 hit.
[Graphical view]
SMARTiSM01165. DUF1866. 1 hit.
SM00128. IPPc. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
SSF56219. SSF56219. 2 hits.
PROSITEiPS50102. RRM. 1 hit.
PS50275. SAC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9JFZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKRWACWSG SDAPGGCGGG CGRRRRRSRR KRAASEERRM AFSKGFRIYH
60 70 80 90 100
KLDPPPFSLI VETRHKEECL MFESGAVAVL SSAEKEAIKG TYSKVLDAYG
110 120 130 140 150
LLGVLRLNLG DTMLHYLVLV TGCMSVGKIQ ESEVFRVTST EFISLRIDSS
160 170 180 190 200
DEDRISEVRK VLNSGNFYFA WSASGISLDL SLNAHRSMQE QTTDNRFFWN
210 220 230 240 250
QSLHLHLKHY GVNCDDWLLR LMCGGVEIRT IYAAHKQAKA CLISRLSCER
260 270 280 290 300
AGTRFNVRGT NDDGHVANFV ETEQVVYLDD SVSSFIQIRG SVPLFWEQPG
310 320 330 340 350
LQVGSHRVRM SRGFEANAPA FDRHFRTLKN LYGKQIIVNL LGSKEGEHML
360 370 380 390 400
SKAFQSHLKA SEHAADIQMV NFDYHQMVKG GKAEKLHSVL KPQVQKFLDY
410 420 430 440 450
GFFYFNGSEV QRCQSGTVRT NCLDCLDRTN SVQAFLGLEM LAKQLEALGL
460 470 480 490 500
AEKPQLVTRF QEVFRSMWSV NGDSISKIYA GTGALEGKAK LKDGARSVTR
510 520 530 540 550
TIQNNFFDSS KQEAIDVLLL GNTLNSDLAD KARALLTTGS LRVSEQTLQS
560 570 580 590 600
ASSKVLKSMC ENFYKYSKPK KIRVCVGTWN VNGGKQFRSI AFKNQTLTDW
610 620 630 640 650
LLDAPKLAGI QEFQDKRSKP TDIFAIGFEE MVELNAGNIV SASTTNQKLW
660 670 680 690 700
AVELQKTISR DNKYVLLASE QLVGVCLFVF IRPQHAPFIR DVAVDTVKTG
710 720 730 740 750
MGGATGNKGA VAIRMLFHTT SLCFVCSHFA AGQSQVKERN EDFIEIARKL
760 770 780 790 800
SFPMGRMLFS HDYVFWCGDF NYRIDLPNEE VKELIRQQNW DSLIAGDQLI
810 820 830 840 850
NQKNAGQVFR GFLEGKVTFA PTYKYDLFSD DYDTSEKCRT PAWTDRVLWR
860 870 880 890 900
RRKWPFDRSA EDLDLLNASF QDESKILYTW TPGTLLHYGR AELKTSDHRP
910 920 930 940 950
VVALIDIDIF EVEAEERQNI YKEVIAVQGP PDGTVLVSIK SSLPENNFFD
960 970 980 990 1000
DALIDELLQQ FASFGEVILI RFVEDKMWVT FLEGSSALNV LSLNGKELLN
1010 1020 1030 1040 1050
RTITIALKSP DWIKNLEEEM SLEKISIALP SSTSSTLLGE DAEVAADFDM
1060 1070 1080 1090 1100
EGDVDDYSAE VEELLPQHLQ PSSSSGLGTS PSSSPRTSPC QSPTISEGPV
1110 1120 1130 1140 1150
PSLPIRPSRA PSRTPGPPSA QSSPIDAQPA TPLPQKDPAQ PLEPKRPPPP
1160 1170 1180 1190 1200
RPVAPPTRPA PPQRPPPPSG ARSPAPTRKE FGGIGAPPSP GVARREMEAP
1210 1220 1230 1240 1250
KSPGTTRKDN IGRSQPSPQA GLAGPGPAGY STARPTIPPR AGVISAPQSH
1260 1270 1280 1290 1300
ARASAGRLTP ESQSKTSETS KGSTFLPEPL KPQAAFPPQS SLPPPAQRLQ
1310 1320 1330 1340 1350
EPLVPVAAPM PQSGPQPNLE TPPQPPPRSR SSHSLPSEAS SQPQQEQPSG
Length:1,350
Mass (Da):149,305
Last modified:November 3, 2009 - v1
Checksum:i0CBDF57D8A208085
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000275 Genomic DNA. No translation available.
AP000276 Genomic DNA. No translation available.
AP000277 Genomic DNA. No translation available.
AP000278 Genomic DNA. No translation available.
AP000279 Genomic DNA. No translation available.
KC877861 Genomic DNA. No translation available.
KF510544 Genomic DNA. No translation available.
RefSeqiNP_982271.2. NM_203446.2.
UniGeneiHs.473632.

Genome annotation databases

EnsembliENST00000382499; ENSP00000371939; ENSG00000159082.
GeneIDi8867.
UCSCiuc002yqi.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000275 Genomic DNA. No translation available.
AP000276 Genomic DNA. No translation available.
AP000277 Genomic DNA. No translation available.
AP000278 Genomic DNA. No translation available.
AP000279 Genomic DNA. No translation available.
KC877861 Genomic DNA. No translation available.
KF510544 Genomic DNA. No translation available.
RefSeqiNP_982271.2. NM_203446.2.
UniGeneiHs.473632.

3D structure databases

ProteinModelPortaliC9JFZ1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000409667.

Proteomic databases

MaxQBiC9JFZ1.
PaxDbiC9JFZ1.
PRIDEiC9JFZ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000382499; ENSP00000371939; ENSG00000159082.
GeneIDi8867.
UCSCiuc002yqi.3. human.

Organism-specific databases

CTDi8867.
HGNCiHGNC:11503. SYNJ1.
OpenTargetsiENSG00000159082.
PharmGKBiPA36285.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0566. Eukaryota.
COG5329. LUCA.
COG5411. LUCA.
GeneTreeiENSGT00760000119075.
HOGENOMiHOG000007937.

Miscellaneous databases

ChiTaRSiSYNJ1. human.
GenomeRNAii8867.

Gene expression databases

BgeeiENSG00000159082.
ExpressionAtlasiC9JFZ1. baseline and differential.
GenevisibleiC9JFZ1. HS.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
3.60.10.10. 1 hit.
InterProiIPR015047. DUF1866.
IPR005135. Endo/exonuclease/phosphatase.
IPR000300. IPPc.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR002013. SAC_dom.
[Graphical view]
PfamiPF08952. DUF1866. 1 hit.
PF03372. Exo_endo_phos. 1 hit.
PF02383. Syja_N. 1 hit.
[Graphical view]
SMARTiSM01165. DUF1866. 1 hit.
SM00128. IPPc. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
SSF56219. SSF56219. 2 hits.
PROSITEiPS50102. RRM. 1 hit.
PS50275. SAC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC9JFZ1_HUMAN
AccessioniPrimary (citable) accession number: C9JFZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: November 30, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.