Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Single Ig IL-1-related receptor

Gene

SIGIRR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Single Ig IL-1-related receptorImported
Gene namesi
Name:SIGIRRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000185187.12
HGNCiHGNC:30575 SIGIRR

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei119 – 140HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185187

PTM / Processingi

Proteomic databases

EPDiC9JFX4
MaxQBiC9JFX4
PRIDEiC9JFX4

Expressioni

Gene expression databases

BgeeiENSG00000185187
ExpressionAtlasiC9JFX4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JFX4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 109Ig-likeInterPro annotationAdd BLAST101
Domaini163 – 310TIRInterPro annotationAdd BLAST148

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEXB Eukaryota
ENOG410ZFDI LUCA
GeneTreeiENSGT00840000129987
HOGENOMiHOG000237348
OMAiEVEMNDG
OrthoDBiEOG091G0GXW
PhylomeDBiC9JFX4

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.40.50.10140, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR015621 IL-1_rcpt_fam
IPR000157 TIR_dom
IPR035897 Toll_tir_struct_dom_sf
PANTHERiPTHR11890 PTHR11890, 1 hit
PfamiView protein in Pfam
PF01582 TIR, 1 hit
SMARTiView protein in SMART
SM00255 TIR, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF52200 SSF52200, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS50104 TIR, 1 hit

Sequencei

Sequence statusi: Complete.

C9JFX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGVCDRAPD FLSPSEDQVL RPALGSSVAL NCTAWVVSGP HCSLPSVQWL
60 70 80 90 100
KDGLPLGIGG HYSLHEYSWV KANLSEVLVS SVLGVNVTST EVYGAFTCSI
110 120 130 140 150
QNISFSSFTL QRAGPTSHVA AVLASLLVLL ALLLAALLYV KCRLNVLLWY
160 170 180 190 200
QDAYGEVEIN DGKLYDAYVS YSDCPEDRKF VNFILKPQLE RRRGYKLFLD
210 220 230 240 250
DRDLLPRAEP SADLLVNLSR CRRLIVVLSD AFLSRAWCSH SFREGLCRLL
260 270 280 290 300
ELTRRPIFIT FEGQRRDPAH PALRLLRQHR HLVTLLLWRP GSVTPSSDFW
310 320 330 340 350
KEVQLALPRK VQYRPVEGDP QTQLQDDKDP MLILRGRVPE GRALDSEVDP
360 370 380 390 400
DPEGDLGMPA QPHSPTGEAQ HRAEWGQAQG TGPGGAPGVE DSSRHREPLH
410 420 430 440 450
GLCPGGARPS VCLGTSWASQ AITAGGEQGQ PLAVGLGQGC GWPPQASRSP
460 470 480 490 500
HPRCPGACLW RAISSTAHQW GLAGREPEQR SGRLGSRLAK LQCPHRLLLP

GVQG
Length:504
Mass (Da):55,221
Last modified:November 3, 2009 - v1
Checksum:iC6A974A6C4ED30C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138230 Genomic DNA No translation available.
RefSeqiXP_005253101.1, XM_005253044.2
XP_005253102.1, XM_005253045.1
XP_005253103.1, XM_005253046.1
UniGeneiHs.501624

Genome annotation databases

EnsembliENST00000531205; ENSP00000433022; ENSG00000185187
GeneIDi59307
UCSCiuc001lpg.4 human

Similar proteinsi

Entry informationi

Entry nameiC9JFX4_HUMAN
AccessioniPrimary (citable) accession number: C9JFX4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health