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Protein
Submitted name:

Single Ig IL-1-related receptor

Gene

SIGIRR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Single Ig IL-1-related receptorImported
Gene namesi
Name:SIGIRRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:30575. SIGIRR.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei119 – 14022HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiC9JFX4.
PaxDbiC9JFX4.

Expressioni

Gene expression databases

BgeeiC9JFX4.
ExpressionAtlasiC9JFX4. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000333656.

Structurei

3D structure databases

ProteinModelPortaliC9JFX4.
SMRiC9JFX4. Positions 163-308.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 109101Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini163 – 310148TIRInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEXB. Eukaryota.
ENOG410ZFDI. LUCA.
GeneTreeiENSGT00840000129987.
HOGENOMiHOG000237348.
OMAiEVEMNDG.
PhylomeDBiC9JFX4.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.40.50.10140. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR015621. IL-1_rcpt_fam.
IPR000157. TIR_dom.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PfamiPF01582. TIR. 1 hit.
[Graphical view]
SMARTiSM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS50104. TIR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9JFX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGVCDRAPD FLSPSEDQVL RPALGSSVAL NCTAWVVSGP HCSLPSVQWL
60 70 80 90 100
KDGLPLGIGG HYSLHEYSWV KANLSEVLVS SVLGVNVTST EVYGAFTCSI
110 120 130 140 150
QNISFSSFTL QRAGPTSHVA AVLASLLVLL ALLLAALLYV KCRLNVLLWY
160 170 180 190 200
QDAYGEVEIN DGKLYDAYVS YSDCPEDRKF VNFILKPQLE RRRGYKLFLD
210 220 230 240 250
DRDLLPRAEP SADLLVNLSR CRRLIVVLSD AFLSRAWCSH SFREGLCRLL
260 270 280 290 300
ELTRRPIFIT FEGQRRDPAH PALRLLRQHR HLVTLLLWRP GSVTPSSDFW
310 320 330 340 350
KEVQLALPRK VQYRPVEGDP QTQLQDDKDP MLILRGRVPE GRALDSEVDP
360 370 380 390 400
DPEGDLGMPA QPHSPTGEAQ HRAEWGQAQG TGPGGAPGVE DSSRHREPLH
410 420 430 440 450
GLCPGGARPS VCLGTSWASQ AITAGGEQGQ PLAVGLGQGC GWPPQASRSP
460 470 480 490 500
HPRCPGACLW RAISSTAHQW GLAGREPEQR SGRLGSRLAK LQCPHRLLLP

GVQG
Length:504
Mass (Da):55,221
Last modified:November 3, 2009 - v1
Checksum:iC6A974A6C4ED30C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138230 Genomic DNA. No translation available.
RefSeqiXP_005253101.1. XM_005253044.2.
XP_005253102.1. XM_005253045.1.
XP_005253103.1. XM_005253046.1.
UniGeneiHs.501624.

Genome annotation databases

EnsembliENST00000531205; ENSP00000433022; ENSG00000185187.
GeneIDi59307.
UCSCiuc001lpg.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138230 Genomic DNA. No translation available.
RefSeqiXP_005253101.1. XM_005253044.2.
XP_005253102.1. XM_005253045.1.
XP_005253103.1. XM_005253046.1.
UniGeneiHs.501624.

3D structure databases

ProteinModelPortaliC9JFX4.
SMRiC9JFX4. Positions 163-308.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000333656.

Proteomic databases

EPDiC9JFX4.
PaxDbiC9JFX4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000531205; ENSP00000433022; ENSG00000185187.
GeneIDi59307.
UCSCiuc001lpg.4. human.

Organism-specific databases

CTDi59307.
HGNCiHGNC:30575. SIGIRR.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IEXB. Eukaryota.
ENOG410ZFDI. LUCA.
GeneTreeiENSGT00840000129987.
HOGENOMiHOG000237348.
OMAiEVEMNDG.
PhylomeDBiC9JFX4.

Miscellaneous databases

ChiTaRSiSIGIRR. human.
GenomeRNAii59307.

Gene expression databases

BgeeiC9JFX4.
ExpressionAtlasiC9JFX4. baseline and differential.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.40.50.10140. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR015621. IL-1_rcpt_fam.
IPR000157. TIR_dom.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PfamiPF01582. TIR. 1 hit.
[Graphical view]
SMARTiSM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS50104. TIR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9JFX4_HUMAN
AccessioniPrimary (citable) accession number: C9JFX4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: June 8, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.