C9JEX1 (C9JEX1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lysyl-bradykinin Ensembl ENSP00000396025

Gene names

Name:

KNG1 Ensembl ENSP00000396025

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000396025

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000396025

Ontologies

Keywords
Molecular function	Protease inhibitor Thiol protease inhibitor SAAS SAAS000010
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	cysteine-type endopeptidase inhibitor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C9JEX1 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: E2126218B3462290	FASTA	391	43,822
	10 20 30 40 50 60 MKLITILFLC SRLLLSLTQE SQSEEIDCND KDLFKAVDAA LKKYNSQNQS NNQFVLYRIT 70 80 90 100 110 120 EATKTVGSDT FYSFKYEIKE GDCPVQSGKT WQDCEYKDAA KAATGECTAT VGKRSSTKFS 130 140 150 160 170 180 VATQTCQITP AEGPVVTAQY DCLGCVHPIS TQSPDLEPIL RHGIQYFNNN TQHSSLFMLN 190 200 210 220 230 240 EVKRAQRQDT GECTDNAYID IQLRIASFSQ NCDIYPGKDF VQPPTKICVG CPRDIPTNSP 250 260 270 280 290 300 ELEETLTHTI TKLNAENNAT FYFKIDNVKK ARVQVVAGKK YFIDFVARET TCSKESNEEL 310 320 330 340 350 360 TESCETKKLG QSLDCNAEVY VVPWEKKIYP TVNCQPLGMI SLMKRPPGFS PFRSSRIGEI 370 380 390 KEETTSHLRS CEYKGRPPKA GAEPASEREV S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC109780 Genomic DNA. No translation available. AC112907 Genomic DNA. No translation available.
IPI	IPI00924859.
RefSeq	NP_001159923.1. NM_001166451.1.
UniGene	Hs.77741.
3D structure databases
ProteinModelPortal	C9JEX1.
SMR	C9JEX1. Positions 229-325.
ModBase	Search...
Protein-protein interaction databases
STRING	C9JEX1.
Protocols and materials databases
DNASU	3827.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000447445; ENSP00000396025; ENSG00000113889.
GeneID	3827.
KEGG	hsa:3827.
UCSC	uc021xil.1. human.
Organism-specific databases
CTD	3827.
HGNC	HGNC:6383. KNG1.
PharmGKB	PA225.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000113239.
KO	K03898.
Gene expression databases
ArrayExpress	C9JEX1.
Bgee	C9JEX1.
Family and domain databases
InterPro	IPR027358. Kininogen-type_cystatin_dom. IPR000010. Prot_inh_cystat. IPR018073. Prot_inh_cystat_CS. [Graphical view]
Pfam	PF00031. Cystatin. 3 hits. [Graphical view]
SMART	SM00043. CY. 3 hits. [Graphical view]
PROSITE	PS00287. CYSTATIN. 1 hit. PS51647. CYSTATIN_KININOGEN. 3 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	KNG1. human.
GenomeRNAi	3827.
NextBio	15047.

Entry information

Entry name

C9JEX1_HUMAN

Accession

Primary (citable) accession number: C9JEX1

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.