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Protein
Submitted name:

Ephrin type-A receptor 4

Gene

EPHA4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin type-A receptor 4Imported
Gene namesi
Name:EPHA4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:3388. EPHA4.

PTM / Processingi

Proteomic databases

PaxDbiC9JEM6.
PeptideAtlasiC9JEM6.

Expressioni

Gene expression databases

BgeeiC9JEM6.
ExpressionAtlasiC9JEM6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000281821.

Structurei

3D structure databases

ProteinModelPortaliC9JEM6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 126126Eph LBD (Eph ligand-binding)InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0196. Eukaryota.
COG0515. LUCA.
GeneTreeiENSGT00760000118975.
HOGENOMiHOG000072585.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
InterProiIPR001090. Ephrin_rcpt_lig-bd_dom.
IPR008979. Galactose-bd-like.
[Graphical view]
PfamiPF01404. Ephrin_lbd. 1 hit.
[Graphical view]
SMARTiSM00615. EPH_lbd. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
PROSITEiPS51550. EPH_LBD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C9JEM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEKNTPIRT YQVCNVMEPS QNNWLRTDWI TREGAQRVYI EIKFTLRDCN
60 70 80 90 100
SLPGVMGTCK ETFNLYYYES DNDKERFIRE NQFVKIDTIA ADESFTQVDI
110 120
GDRIMKLNTE IRDVGPLSKK GFYLAF
Length:126
Mass (Da):14,854
Last modified:November 3, 2009 - v1
Checksum:iC81E7A9E60C66A9C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei126 – 1261Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010899 Genomic DNA. No translation available.
AC079834 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000419964; ENSP00000410158; ENSG00000116106.
UCSCiuc061tbc.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010899 Genomic DNA. No translation available.
AC079834 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliC9JEM6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000281821.

Proteomic databases

PaxDbiC9JEM6.
PeptideAtlasiC9JEM6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000419964; ENSP00000410158; ENSG00000116106.
UCSCiuc061tbc.1. human.

Organism-specific databases

HGNCiHGNC:3388. EPHA4.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0196. Eukaryota.
COG0515. LUCA.
GeneTreeiENSGT00760000118975.
HOGENOMiHOG000072585.

Miscellaneous databases

ChiTaRSiEPHA4. human.

Gene expression databases

BgeeiC9JEM6.
ExpressionAtlasiC9JEM6. baseline and differential.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
InterProiIPR001090. Ephrin_rcpt_lig-bd_dom.
IPR008979. Galactose-bd-like.
[Graphical view]
PfamiPF01404. Ephrin_lbd. 1 hit.
[Graphical view]
SMARTiSM00615. EPH_lbd. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
PROSITEiPS51550. EPH_LBD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9JEM6_HUMAN
AccessioniPrimary (citable) accession number: C9JEM6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: July 6, 2016
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.