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Protein
Submitted name:

Voltage-dependent calcium channel subunit alpha-2/delta-2

Gene

CACNA2D2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent calcium channel subunit alpha-2/delta-2Imported
Gene namesi
Name:CACNA2D2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000007402.11.
HGNCiHGNC:1400. CACNA2D2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000007402.

PTM / Processingi

Proteomic databases

MaxQBiC9JE82.
PaxDbiC9JE82.
PRIDEiC9JE82.

Expressioni

Gene expression databases

BgeeiENSG00000007402.
ExpressionAtlasiC9JE82. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JE82.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini291 – 469VWFAInterPro annotationAdd BLAST179

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili123 – 147Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2353. Eukaryota.
ENOG410XPDX. LUCA.
GeneTreeiENSGT00530000062904.
HOGENOMiHOG000004860.

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiView protein in InterPro
IPR013680. VDCC_a2/dsu.
IPR013608. VWA_N.
IPR002035. VWF_A.
IPR036465. vWFA_dom_sf.
PfamiView protein in Pfam
PF08473. VGCC_alpha2. 1 hit.
PF00092. VWA. 1 hit.
PF08399. VWA_N. 1 hit.
SMARTiView protein in SMART
SM00327. VWA. 1 hit.
SUPFAMiSSF53300. SSF53300. 1 hit.
PROSITEiView protein in PROSITE
PS50234. VWFA. 1 hit.

Sequencei

Sequence statusi: Complete.

C9JE82-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVPARTCGA SRPGPARTAR PWPGCGPHPG PGTRRPTSGP PRPLWLLLPL
60 70 80 90 100
LPLLAAPGAS AYSFPQQHTM QHWARRLEQE VDGVMRIFGG VQQLREIYKD
110 120 130 140 150
NRNLFEVQEN EPQKLVEKVA GDIESLLDRK VQALKRLADA AENFQKAHRW
160 170 180 190 200
QDNIKEEDIV YYDAKADAEL DDPESEDVER GSKASTLRLD FIEDPNFKNK
210 220 230 240 250
VNYSYAAVQI PTDIYKGSTV ILNELNWTEA LENVFMENRR QDPTLLWQVF
260 270 280 290 300
GSATGVTRYY PATPWRAPKK IDLYDVRRRP WYIQGASSPK DMVIIVDVSG
310 320 330 340 350
SVSGLTLKLM KTSVCEMLDT LSDDDYVNVA SFNEKAQPVS CFTHLVQANV
360 370 380 390 400
RNKKVFKEAV QGMVAKGTTG YKAGFEYAFD QLQNSNITRA NCNKMIMMFT
410 420 430 440 450
DGGEDRVQDV FEKYNWPNRT VRVFTFSVGQ HNYDVTPLQW MACANKGYYF
460 470 480 490 500
EIPSIGAIRI NTQEYLDVLG RPMVLAGKEA KQVQWTNVYE DALGLGLVVT
510 520 530 540 550
GTLPVFNLTQ DGPGEKKNQL ILGVMGIDVA LNDIKRLTPN YTLGANGYVF
560 570 580 590 600
AIDLNGYVLL HPNLKPQTTN FREPVTLDFL DAELEDENKE EIRRSMIDGN
610 620 630 640 650
KGHKQIRTLV KSLDERYIDE VTRNYTWVPI RSTNYSLGLV LPPYSTFYLQ
660 670 680 690 700
ANLSDQILQV KYFEFLLPSS FESEGHVFIA PREYCKDLNA SDNNTEFLKN
710 720 730 740 750
FIELMEKVTP DSKQCNNFLL HNLILDTGIT QQLVERVWRD QDLNTYSLLA
760 770 780 790 800
VFAATDGGIT RVFPNKAAED WTENPEPFNA SFYRRSLDNH GYVFKPPHQD
810 820 830 840 850
ALLRPLELEN DTVGILVSTA VELSLGRRTL RPAVVGVKLD LEAWAEKFKV
860 870 880 890 900
LASNRTHQDQ PQKQCGPNSH CEMDCEVNNE DLLCVLIDDG GFLVLSNQNH
910 920 930 940 950
QWDQVGRFFS EVDANLMLAL YNNSFYTRKE SYDYQAACAP QPPGNLGAAP
960 970 980 990 1000
RGVFVPTVAD FLNLAWWTSA AAWSLFQQLL YGLIYHSWFQ ADPAEAEGSP
1010 1020 1030 1040 1050
ETRESSCVMK QTQYYFGSVN ASYNAIIDCG NCSRLFHAQR LTNTNLLFVV
1060 1070 1080 1090 1100
AEKPLCSQCE AGRLLQKETH SDGPEQCELV QRPRYRRGPH ICFDYNATED
1110 1120 1130 1140
TSDCGRGASF PPSLGVLVSL QLLLLLGLPP RPQPQVLVHA SRRL
Length:1,144
Mass (Da):129,213
Last modified:November 3, 2009 - v1
Checksum:i540E2257ACB3204E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL450422 Genomic DNA. No translation available.
KF457634 Genomic DNA. No translation available.
Z75742 Genomic DNA. No translation available.
Z75743 Genomic DNA. No translation available.
Z84492 Genomic DNA. No translation available.
Z84494 Genomic DNA. No translation available.
Z84495 Genomic DNA. No translation available.
RefSeqiXP_005265638.1. XM_005265581.4.
UniGeneiHs.476273.
Hs.674666.

Genome annotation databases

EnsembliENST00000429770; ENSP00000404631; ENSG00000007402.
GeneIDi9254.
UCSCiuc062kfi.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9JE82_HUMAN
AccessioniPrimary (citable) accession number: C9JE82
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: October 25, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported