Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

WD repeat-containing protein 76

Gene

WDR76

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.UniRule annotation

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
WD repeat-containing protein 76UniRule annotation
Gene namesi
Name:WDR76Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000092470.11
HGNCiHGNC:25773 WDR76

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000092470

PTM / Processingi

Proteomic databases

MaxQBiC9JE56
PeptideAtlasiC9JE56
PRIDEiC9JE56

Expressioni

Gene expression databases

BgeeiENSG00000092470
ExpressionAtlasiC9JE56 baseline and differential

Interactioni

Subunit structurei

Interacts with CUL4A and/or CUL4B.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliC9JE56
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the WD repeat DDB2/WDR76 family.UniRule annotation

Keywords - Domaini

WD repeatUniRule annotation

Phylogenomic databases

eggNOGiKOG4328 Eukaryota
ENOG410XRID LUCA
GeneTreeiENSGT00510000048144
HOGENOMiHOG000081507

Family and domain databases

InterProiView protein in InterPro
IPR033052 Cmr1/WDR76
PANTHERiPTHR14773:SF0 PTHR14773:SF0, 2 hits

Sequencei

Sequence statusi: Fragment.

C9JE56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCPKSLSEKN SNNEVACKKT KIKKTCRRII PPKMKNTSSK AESTLQNSSS
60 70 80 90 100
AVHTESNKLQ PKRTADAMNL SVDVESSQDG DSDEDTTPSL DFSGLSPYER
110 120 130 140 150
KRLKNISENA DFFASLQLSE SAARLREMIE KRQPPKSKRK KPKRENGIGC
160 170 180 190 200
RRSMRLLKVD PSGVSLPAAP TPPTLVADET PLLPPGPLEM TSENQEDNNE
210 220
RFKGFLHTWA GMSKPSSKNT EKGLSSIK
Length:228
Mass (Da):25,218
Last modified:November 3, 2009 - v1
Checksum:i0C881BE0DE04811A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei228Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018512 Genomic DNA No translation available.
AC023356 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000452115; ENSP00000404665; ENSG00000092470
UCSCiuc059inv.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JE56_HUMAN
AccessioniPrimary (citable) accession number: C9JE56
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 23, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health