ARHGEF7

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Rho guanine nucleotide exchange factor 7Imported
Gene namesⁱ	Name:ARHGEF7Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 13

Organism-specific databases

HGNCⁱ

HGNC:15607. ARHGEF7.

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000102606.

OpenTargetsⁱ

ENSG00000102606.

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9JDI6.
PaxDbⁱ	C9JDI6.
PeptideAtlas More...PeptideAtlasⁱ	C9JDI6.
PRIDEⁱ	C9JDI6.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000102606.
ExpressionAtlasⁱ	C9JDI6. baseline and differential.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	C9JDI6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	6 – 61	SH3InterPro annotationAdd BLAST		56

Keywords - Domainⁱ

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG2070. Eukaryota. ENOG410XNNP. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118925.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001452. SH3_domain.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF14604. SH3_9. 1 hit.
PRINTSⁱ	PR00452. SH3DOMAIN.
SMARTⁱ	View protein in SMART SM00326. SH3. 1 hit.
SUPFAMⁱ	SSF50044. SSF50044. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50002. SH3. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

C9JDI6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTDNSNNQLV VRAKFNFQQT NEDELSFSKG DVIHVTRVEE GGWWEGTLNG 
        60 
RTGWFPSNYV R

Length:61

Mass (Da):7,064

Last modified:November 3, 2009 - v1

Checksum:ⁱD0CB868AFCC4B595

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	61	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL139086 Genomic DNA. No translation available. AL353704 Genomic DNA. No translation available. AL390754 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL139086 Genomic DNA. No translation available.
AL353704 Genomic DNA. No translation available.
AL390754 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000467053; ENSP00000420592; ENSG00000102606.
UCSC genome browser More...UCSCⁱ	uc058yij.1. human.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL139086 Genomic DNA. No translation available. AL353704 Genomic DNA. No translation available. AL390754 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL139086 Genomic DNA. No translation available.
AL353704 Genomic DNA. No translation available.
AL390754 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalⁱ	C9JDI6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9JDI6.
PaxDbⁱ	C9JDI6.
PeptideAtlas More...PeptideAtlasⁱ	C9JDI6.
PRIDEⁱ	C9JDI6.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000467053; ENSP00000420592; ENSG00000102606.
UCSC genome browser More...UCSCⁱ	uc058yij.1. human.

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:15607. ARHGEF7.
Open Targets More...OpenTargetsⁱ	ENSG00000102606.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2070. Eukaryota. ENOG410XNNP. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118925.

Miscellaneous databases

ChiTaRSⁱ	ARHGEF7. human.

ChiTaRSⁱ

ARHGEF7. human.

Gene expression databases

Bgeeⁱ	ENSG00000102606.
ExpressionAtlasⁱ	C9JDI6. baseline and differential.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001452. SH3_domain.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF14604. SH3_9. 1 hit.
PRINTSⁱ	PR00452. SH3DOMAIN.
SMARTⁱ	View protein in SMART SM00326. SH3. 1 hit.
SUPFAMⁱ	SSF50044. SSF50044. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50002. SH3. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	C9JDI6_HUMAN
Accessionⁱ	C9JDI6Primary (citable) accession number: C9JDI6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 3, 2009
	Last sequence update:	November 3, 2009
	Last modified:	July 5, 2017
	This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB - C9JDI6 (C9JDI6_HUMAN)

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Rho guanine nucleotide exchange factor 7

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Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Caution

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - C9JDI6 (C9JDI6_HUMAN)

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Rho guanine nucleotide exchange factor 7

ARHGEF7

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ