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Protein
Submitted name:

Acetylcholinesterase

Gene

ACHE

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Protein family/group databases

ESTHERihuman-ACHE AChE

Names & Taxonomyi

Protein namesi
Submitted name:
AcetylcholinesteraseImported
Gene namesi
Name:ACHEImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000087085.13
HGNCiHGNC:108 ACHE

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087085

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Sequence analysisAdd BLAST33
ChainiPRO_500841292234 – 158Sequence analysisAdd BLAST125

Proteomic databases

PeptideAtlasiC9JD78

Expressioni

Gene expression databases

BgeeiENSG00000087085
ExpressionAtlasiC9JD78 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JD78
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 157COesteraseInterPro annotationAdd BLAST119

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4389 Eukaryota
COG2272 LUCA
GeneTreeiENSGT00760000118946
HOGENOMiHOG000091866

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR002018 CarbesteraseB
IPR019819 Carboxylesterase_B_CS
IPR000997 Cholinesterase
PfamiView protein in Pfam
PF00135 COesterase, 1 hit
PRINTSiPR00878 CHOLNESTRASE
SUPFAMiSSF53474 SSF53474, 1 hit
PROSITEiView protein in PROSITE
PS00941 CARBOXYLESTERASE_B_2, 1 hit

Sequencei

Sequence statusi: Fragment.

C9JD78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPPQCLLHT PSLASPLLLL LLWLLGGGVG AEGREDAELL VTVRGGRLRG
60 70 80 90 100
IRLKTPGGPV SAFLGIPFAE PPMGPRRFLP PEPKQPWSGV VDATTFQSVC
110 120 130 140 150
YQYVDTLYPG FEGTEMWNPN RELSEDCLYL NVWTPYPRPT SPTPVLVWIY

GGGFYSGA
Length:158
Mass (Da):17,358
Last modified:October 5, 2016 - v8
Checksum:iB94EA5F86362DAF9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei158Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011895 Genomic DNA No translation available.
KF510962 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000441605; ENSP00000396360; ENSG00000087085
UCSCiuc064gjk.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JD78_HUMAN
AccessioniPrimary (citable) accession number: C9JD78
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: May 23, 2018
This is version 60 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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