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Protein
Submitted name:

Acetylcholinesterase

Gene

ACHE

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Protein family/group databases

ESTHERihuman-ACHE. AChE.

Names & Taxonomyi

Protein namesi
Submitted name:
AcetylcholinesteraseImported
Gene namesi
Name:ACHEImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000087085.13.
HGNCiHGNC:108. ACHE.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087085.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Sequence analysisAdd BLAST33
ChainiPRO_500841292234 – 158Sequence analysisAdd BLAST125

Proteomic databases

PaxDbiC9JD78.
PeptideAtlasiC9JD78.

Expressioni

Gene expression databases

BgeeiENSG00000087085.
ExpressionAtlasiC9JD78. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JD78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 157COesteraseInterPro annotationAdd BLAST119

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4389. Eukaryota.
COG2272. LUCA.
GeneTreeiENSGT00760000118946.
HOGENOMiHOG000091866.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019819. Carboxylesterase_B_CS.
IPR000997. Cholinesterase.
PfamiView protein in Pfam
PF00135. COesterase. 1 hit.
PRINTSiPR00878. CHOLNESTRASE.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiView protein in PROSITE
PS00941. CARBOXYLESTERASE_B_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9JD78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPPQCLLHT PSLASPLLLL LLWLLGGGVG AEGREDAELL VTVRGGRLRG
60 70 80 90 100
IRLKTPGGPV SAFLGIPFAE PPMGPRRFLP PEPKQPWSGV VDATTFQSVC
110 120 130 140 150
YQYVDTLYPG FEGTEMWNPN RELSEDCLYL NVWTPYPRPT SPTPVLVWIY

GGGFYSGA
Length:158
Mass (Da):17,358
Last modified:October 5, 2016 - v8
Checksum:iB94EA5F86362DAF9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei158Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011895 Genomic DNA. No translation available.
KF510962 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000441605; ENSP00000396360; ENSG00000087085.
UCSCiuc064gjk.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9JD78_HUMAN
AccessioniPrimary (citable) accession number: C9JD78
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: September 27, 2017
This is version 57 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported