ID   C9JCT1_HUMAN            Unreviewed;       141 AA.
AC   C9JCT1;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Kallikrein B1 {ECO:0000313|Ensembl:ENSP00000415563.2};
DE   Flags: Fragment;
GN   Name=KLKB1 {ECO:0000313|Ensembl:ENSP00000415563.2};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000415563.2, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000415563.2, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000415563.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC110771; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; C9JCT1; -.
DR   SMR; C9JCT1; -.
DR   MassIVE; C9JCT1; -.
DR   PeptideAtlas; C9JCT1; -.
DR   ProteomicsDB; 9638; -.
DR   Antibodypedia; 850; 446 antibodies from 36 providers.
DR   Ensembl; ENST00000446598.6; ENSP00000415563.2; ENSG00000164344.17.
DR   UCSC; uc063boh.1; human.
DR   HGNC; HGNC:6371; KLKB1.
DR   VEuPathDB; HostDB:ENSG00000164344; -.
DR   GeneTree; ENSGT00940000161669; -.
DR   HOGENOM; CLU_147746_0_0_1; -.
DR   OMA; TAMYTPN; -.
DR   ChiTaRS; KLKB1; human.
DR   Proteomes; UP000005640; Chromosome 4.
DR   Bgee; ENSG00000164344; Expressed in right lobe of liver and 125 other cell types or tissues.
DR   ExpressionAtlas; C9JCT1; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd01100; APPLE_Factor_XI_like; 2.
DR   Gene3D; 3.50.4.10; Hepatocyte Growth Factor; 2.
DR   InterPro; IPR000177; Apple.
DR   InterPro; IPR003609; Pan_app.
DR   PANTHER; PTHR33946; -; 1.
DR   PANTHER; PTHR33946:SF4; COAGULATION FACTOR XI; 1.
DR   Pfam; PF00024; PAN_1; 2.
DR   PRINTS; PR00005; APPLEDOMAIN.
DR   SMART; SM00223; APPLE; 2.
DR   PROSITE; PS50948; PAN; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|PeptideAtlas:C9JCT1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          73..141
FT                   /note="Apple"
FT                   /evidence="ECO:0000259|PROSITE:PS50948"
FT   NON_TER         141
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000415563.2"
SQ   SEQUENCE   141 AA;  15933 MW;  8D710D44C9984AD2 CRC64;
     MYTPNAQYCQ MRCTFHPRCL LFSFLPASSI NDMEKRFGCF LKDSVTGTLP KVHRTGAVSG
     HSLKQCGHQI SACHRDIYKG VDMRGVNFNV SKVSSVEECQ KRCTSNIRCQ FFSYATQTFH
     KAEYRNNCLL KYSPGGTPTA I
//