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Protein
Submitted name:

Plasma kallikrein

Gene

KLKB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. blood coagulation Source: InterPro
  2. proteolysis Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Plasma kallikreinImported
Gene namesi
Name:KLKB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 4

Organism-specific databases

HGNCiHGNC:6371. KLKB1.

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiC9JCT1.
ExpressionAtlasiC9JCT1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JCT1.
SMRiC9JCT1. Positions 1-141.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118962.
HOGENOMiHOG000213704.

Family and domain databases

InterProiIPR000177. Apple.
IPR003014. PAN-1_domain.
IPR003609. Pan_app.
[Graphical view]
PfamiPF00024. PAN_1. 2 hits.
[Graphical view]
PRINTSiPR00005. APPLEDOMAIN.
SMARTiSM00223. APPLE. 2 hits.
[Graphical view]
PROSITEiPS50948. PAN. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C9JCT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYTPNAQYCQ MRCTFHPRCL LFSFLPASSI NDMEKRFGCF LKDSVTGTLP
60 70 80 90 100
KVHRTGAVSG HSLKQCGHQI SACHRDIYKG VDMRGVNFNV SKVSSVEECQ
110 120 130 140
KRCTSNIRCQ FFSYATQTFH KAEYRNNCLL KYSPGGTPTA I
Length:141
Mass (Da):15,933
Last modified:November 3, 2009 - v1
Checksum:i8D710D44C9984AD2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei141 – 1411Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110771 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000446598; ENSP00000415563; ENSG00000164344.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110771 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliC9JCT1.
SMRiC9JCT1. Positions 1-141.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000446598; ENSP00000415563; ENSG00000164344.

Organism-specific databases

HGNCiHGNC:6371. KLKB1.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118962.
HOGENOMiHOG000213704.

Miscellaneous databases

NextBioi35486005.

Gene expression databases

BgeeiC9JCT1.
ExpressionAtlasiC9JCT1. baseline and differential.

Family and domain databases

InterProiIPR000177. Apple.
IPR003014. PAN-1_domain.
IPR003609. Pan_app.
[Graphical view]
PfamiPF00024. PAN_1. 2 hits.
[Graphical view]
PRINTSiPR00005. APPLEDOMAIN.
SMARTiSM00223. APPLE. 2 hits.
[Graphical view]
PROSITEiPS50948. PAN. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9JCT1_HUMAN
AccessioniPrimary (citable) accession number: C9JCT1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: March 4, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationPeptideAtlas annotation, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.