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Protein

Heat shock factor-binding protein 1-like protein 1

Gene

HSBP1L1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock factor-binding protein 1-like protein 1
Gene namesi
Name:HSBP1L1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000226742.3.
HGNCiHGNC:37243. HSBP1L1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000226742.
PharmGKBiPA165429036.

Polymorphism and mutation databases

BioMutaiHSBP1L1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003946621 – 74Heat shock factor-binding protein 1-like protein 1Add BLAST74

Proteomic databases

PaxDbiC9JCN9.
PRIDEiC9JCN9.
TopDownProteomicsiC9JCN9.

PTM databases

iPTMnetiC9JCN9.
PhosphoSitePlusiC9JCN9.

Expressioni

Gene expression databases

BgeeiENSG00000226742.
ExpressionAtlasiC9JCN9. baseline and differential.
GenevisibleiC9JCN9. HS.

Organism-specific databases

HPAiHPA048273.

Interactioni

Protein-protein interaction databases

IntActiC9JCN9. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliC9JCN9.
SMRiC9JCN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili12 – 65Sequence analysisAdd BLAST54

Sequence similaritiesi

Belongs to the HSBP1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410JH4K. Eukaryota.
ENOG4111AKH. LUCA.
GeneTreeiENSGT00550000076117.
HOGENOMiHOG000217518.
HOVERGENiHBG101197.
InParanoidiC9JCN9.
OMAiNLRMEEM.
OrthoDBiEOG091G14ZN.
PhylomeDBiC9JCN9.

Family and domain databases

InterProiView protein in InterPro
IPR009643. HS1-bd.
PANTHERiPTHR19424. PTHR19424. 1 hit.
PfamiView protein in Pfam
PF06825. HSBP1. 1 hit.

Sequencei

Sequence statusi: Complete.

C9JCN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVRGPEAPG GRALRDAAEN LFQELQEHFQ ALTATLNLRM EEMGNRIEDL
60 70
QKNVKDLMVQ AGIENSIKEQ MLKT
Length:74
Mass (Da):8,384
Last modified:June 15, 2010 - v2
Checksum:i92AF41A11C23FACB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti55K → N in AAI57849 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090360 Genomic DNA. No translation available.
AC114341 Genomic DNA. No translation available.
CH471117 Genomic DNA. Translation: EAW66638.1.
BC157848 mRNA. Translation: AAI57849.1.
CCDSiCCDS45886.1.
RefSeqiNP_001129652.1. NM_001136180.1.
UniGeneiHs.191582.

Genome annotation databases

EnsembliENST00000451882; ENSP00000414236; ENSG00000226742.
GeneIDi440498.
KEGGihsa:440498.
UCSCiuc002lno.5. human.

Similar proteinsi

Entry informationi

Entry nameiHSBPL_HUMAN
AccessioniPrimary (citable) accession number: C9JCN9
Secondary accession number(s): B2RXG9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: September 27, 2017
This is version 54 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families