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Protein

Heat shock factor-binding protein 1-like protein 1

Gene

HSBP1L1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock factor-binding protein 1-like protein 1
Gene namesi
Name:HSBP1L1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 18

Organism-specific databases

HGNCiHGNC:37243. HSBP1L1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165429036.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7474Heat shock factor-binding protein 1-like protein 1PRO_0000394662Add
BLAST

Proteomic databases

PaxDbiC9JCN9.
PRIDEiC9JCN9.

PTM databases

PhosphoSiteiC9JCN9.

Expressioni

Gene expression databases

BgeeiC9JCN9.
ExpressionAtlasiC9JCN9. baseline and differential.

Organism-specific databases

HPAiHPA048273.

Interactioni

Protein-protein interaction databases

IntActiC9JCN9. 1 interaction.
STRINGi9606.ENSP00000414236.

Structurei

3D structure databases

ProteinModelPortaliC9JCN9.
SMRiC9JCN9. Positions 11-55.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili12 – 6554Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the HSBP1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG327437.
GeneTreeiENSGT00550000076117.
HOGENOMiHOG000217518.
HOVERGENiHBG101197.
InParanoidiC9JCN9.
OMAiNLRMEEM.
OrthoDBiEOG754HS8.
PhylomeDBiC9JCN9.

Family and domain databases

InterProiIPR009643. HS1-bd.
[Graphical view]
PANTHERiPTHR19424. PTHR19424. 1 hit.
PfamiPF06825. HSBP1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9JCN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVRGPEAPG GRALRDAAEN LFQELQEHFQ ALTATLNLRM EEMGNRIEDL
60 70
QKNVKDLMVQ AGIENSIKEQ MLKT
Length:74
Mass (Da):8,384
Last modified:June 14, 2010 - v2
Checksum:i92AF41A11C23FACB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti55 – 551K → N in AAI57849 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090360 Genomic DNA. No translation available.
AC114341 Genomic DNA. No translation available.
CH471117 Genomic DNA. Translation: EAW66638.1.
BC157848 mRNA. Translation: AAI57849.1.
CCDSiCCDS45886.1.
RefSeqiNP_001129652.1. NM_001136180.1.
UniGeneiHs.191582.

Genome annotation databases

EnsembliENST00000451882; ENSP00000414236; ENSG00000226742.
GeneIDi440498.
KEGGihsa:440498.
UCSCiuc002lno.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090360 Genomic DNA. No translation available.
AC114341 Genomic DNA. No translation available.
CH471117 Genomic DNA. Translation: EAW66638.1.
BC157848 mRNA. Translation: AAI57849.1.
CCDSiCCDS45886.1.
RefSeqiNP_001129652.1. NM_001136180.1.
UniGeneiHs.191582.

3D structure databases

ProteinModelPortaliC9JCN9.
SMRiC9JCN9. Positions 11-55.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiC9JCN9. 1 interaction.
STRINGi9606.ENSP00000414236.

PTM databases

PhosphoSiteiC9JCN9.

Proteomic databases

PaxDbiC9JCN9.
PRIDEiC9JCN9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000451882; ENSP00000414236; ENSG00000226742.
GeneIDi440498.
KEGGihsa:440498.
UCSCiuc002lno.4. human.

Organism-specific databases

CTDi440498.
GeneCardsiGC18P077724.
HGNCiHGNC:37243. HSBP1L1.
HPAiHPA048273.
neXtProtiNX_C9JCN9.
PharmGKBiPA165429036.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG327437.
GeneTreeiENSGT00550000076117.
HOGENOMiHOG000217518.
HOVERGENiHBG101197.
InParanoidiC9JCN9.
OMAiNLRMEEM.
OrthoDBiEOG754HS8.
PhylomeDBiC9JCN9.

Miscellaneous databases

GenomeRNAii440498.
NextBioi109294.
PROiC9JCN9.

Gene expression databases

BgeeiC9JCN9.
ExpressionAtlasiC9JCN9. baseline and differential.

Family and domain databases

InterProiIPR009643. HS1-bd.
[Graphical view]
PANTHERiPTHR19424. PTHR19424. 1 hit.
PfamiPF06825. HSBP1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiHSBPL_HUMAN
AccessioniPrimary (citable) accession number: C9JCN9
Secondary accession number(s): B2RXG9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 14, 2010
Last sequence update: June 14, 2010
Last modified: January 6, 2015
This is version 38 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.