FOSL2

Functionⁱ

GO - Molecular functionⁱ

sequence-specific DNA binding Source: InterPro
transcription factor activity, sequence-specific DNA binding Source: InterPro

GO - Biological processⁱ

regulation of transcription from RNA polymerase II promoter Source: InterPro

Complete GO annotation...

Keywords - Ligandⁱ

DNA-bindingSAAS annotation

Enzyme and pathway databases

SignaLinkⁱ	C9JCN8.

SignaLinkⁱ

C9JCN8.

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Fos-related antigen 2Imported Automatic assertion inferred from database entriesⁱ Ensembl:ENSP00000396497
Gene namesⁱ	Name:FOSL2Imported Automatic assertion inferred from database entriesⁱ Ensembl:ENSP00000396497
Organismⁱ	Homo sapiens (Human)Imported Automatic assertion inferred from database entriesⁱ Ensembl:ENSP00000396497 Proteomes:UP000005640
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 2

Organism-specific databases

HGNCⁱ

HGNC:3798. FOSL2.

PTM / Processingⁱ

Proteomic databases

EPDⁱ	C9JCN8.
PaxDbⁱ	C9JCN8.
PeptideAtlasⁱ	C9JCN8.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000075426.
ExpressionAtlasⁱ	C9JCN8. baseline and differential.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000264716.

STRINGⁱ

9606.ENSP00000264716.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	C9JCN8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Domainⁱ	85 – 148	64	BZIP (basic-leucine zipper)InterPro annotation Automatic assertion inferred from signature matchⁱ PROSITE:PS50217			Add BLAST

Coiled coil

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Coiled coilⁱ	83 – 144	62	Sequence analysis Automatic assertion according to rulesⁱ SAM:Coils			Add BLAST

Sequence similaritiesⁱ

Belongs to the bZIP family.SAAS annotation

Contains bZIP (basic-leucine zipper) domain.SAAS annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG1414. Eukaryota. ENOG4111CH5. LUCA.
GeneTreeⁱ	ENSGT00730000110541.
HOGENOMⁱ	HOG000234334.

Family and domain databases

InterProⁱ	IPR000837. AP-1. IPR004827. bZIP. IPR029814. Fra2. [Graphical view]
PANTHERⁱ	PTHR23351. PTHR23351. 1 hit. PTHR23351:SF25. PTHR23351:SF25. 1 hit.
Pfamⁱ	PF00170. bZIP_1. 1 hit. [Graphical view]
PRINTSⁱ	PR00042. LEUZIPPRFOS.
SMARTⁱ	SM00338. BRLZ. 1 hit. [Graphical view]
PROSITEⁱ	PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Fragment.

C9JCN8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPGSGSAFIP TINAITTSQD LQWMVQPTVI TSMSNPYPRS HPYSPLPGLA 
        60         70         80         90        100
SVPGHMALPR PGVIKTIGTT VGRRRRDEQL SPEEEEKRRI RRERNKLAAA 
       110        120        130        140        150
KCRNRRRELT EKLQAETEEL EEEKSGLQKE IAELQKEKEK LEFMLVAHGP 
       160        170        180        190        200
VCKISPEERR SPPAPGLQPM RSGGGSVGAV VVKQEPLEED SPSSSSAGLD 

KA

Length:202

Mass (Da):22,254

Last modified:November 3, 2009 - v1

Checksum:ⁱ7D32120CEDC46E84

GO

Experimental Info

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Non-terminal residueⁱ	202 – 202	1	Imported Automatic assertion inferred from database entriesⁱ Ensembl:ENSP00000396497

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC104695 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC104695 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000436647; ENSP00000396497; ENSG00000075426.
UCSCⁱ	uc061hsd.1. human.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC104695 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC104695 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalⁱ	C9JCN8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000264716.

STRINGⁱ

9606.ENSP00000264716.

Proteomic databases

EPDⁱ	C9JCN8.
PaxDbⁱ	C9JCN8.
PeptideAtlasⁱ	C9JCN8.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000436647; ENSP00000396497; ENSG00000075426.
UCSCⁱ	uc061hsd.1. human.

Organism-specific databases

HGNCⁱ	HGNC:3798. FOSL2.
GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1414. Eukaryota. ENOG4111CH5. LUCA.
GeneTreeⁱ	ENSGT00730000110541.
HOGENOMⁱ	HOG000234334.

Enzyme and pathway databases

SignaLinkⁱ	C9JCN8.

SignaLinkⁱ

C9JCN8.

Miscellaneous databases

ChiTaRSⁱ	FOSL2. human.

ChiTaRSⁱ

FOSL2. human.

Gene expression databases

Bgeeⁱ	ENSG00000075426.
ExpressionAtlasⁱ	C9JCN8. baseline and differential.

Family and domain databases

InterProⁱ	IPR000837. AP-1. IPR004827. bZIP. IPR029814. Fra2. [Graphical view]
PANTHERⁱ	PTHR23351. PTHR23351. 1 hit. PTHR23351:SF25. PTHR23351:SF25. 1 hit.
Pfamⁱ	PF00170. bZIP_1. 1 hit. [Graphical view]
PRINTSⁱ	PR00042. LEUZIPPRFOS.
SMARTⁱ	SM00338. BRLZ. 1 hit. [Graphical view]
PROSITEⁱ	PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

C9JCN8_HUMAN

Accessionⁱ

Primary (citable) accession number: C9JCN8

Entry historyⁱ

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - C9JCN8 (C9JCN8_HUMAN)

UniProt

C9JCN8 - C9JCN8_HUMAN

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Fos-related antigen 2

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ