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C9JCN8

- C9JCN8_HUMAN

UniProt

C9JCN8 - C9JCN8_HUMAN

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Protein
Submitted name: Fos-related antigen 2
Gene
FOSL2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl
  2. double-stranded DNA binding Source: Ensembl
  3. sequence-specific DNA binding transcription factor activity Source: Ensembl

GO - Biological processi

  1. cellular response to hormone stimulus Source: Ensembl
  2. female pregnancy Source: Ensembl
  3. positive regulation of fibroblast proliferation Source: Ensembl
  4. response to cAMP Source: Ensembl
  5. response to corticosterone Source: Ensembl
  6. response to drug Source: Ensembl
  7. response to mechanical stimulus Source: Ensembl
  8. response to morphine Source: Ensembl
  9. response to progesterone Source: Ensembl
  10. transcription from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

DNA-bindingSAAS annotations

Enzyme and pathway databases

SignaLinkiC9JCN8.

Names & Taxonomyi

Protein namesi
Submitted name:
Fos-related antigen 2Imported
Gene namesi
Name:FOSL2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:3798. FOSL2.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiC9JCN8.
BgeeiC9JCN8.

Structurei

3D structure databases

ProteinModelPortaliC9JCN8.
SMRiC9JCN8. Positions 86-148.

Family & Domainsi

Sequence similaritiesi

Contains bZIP (basic-leucine zipper) domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000234334.

Family and domain databases

InterProiIPR004827. bZIP.
IPR000837. Leuzip_Fos.
[Graphical view]
PfamiPF00170. bZIP_1. 1 hit.
[Graphical view]
PRINTSiPR00042. LEUZIPPRFOS.
SMARTiSM00338. BRLZ. 1 hit.
[Graphical view]
PROSITEiPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C9JCN8-1 [UniParc]FASTAAdd to Basket

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MPGSGSAFIP TINAITTSQD LQWMVQPTVI TSMSNPYPRS HPYSPLPGLA    50
SVPGHMALPR PGVIKTIGTT VGRRRRDEQL SPEEEEKRRI RRERNKLAAA 100
KCRNRRRELT EKLQAETEEL EEEKSGLQKE IAELQKEKEK LEFMLVAHGP 150
VCKISPEERR SPPAPGLQPM RSGGGSVGAV VVKQEPLEED SPSSSSAGLD 200
KA 202
Length:202
Mass (Da):22,254
Last modified:November 3, 2009 - v1
Checksum:i7D32120CEDC46E84
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei202 – 2021Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC104695 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000436647; ENSP00000396497; ENSG00000075426.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC104695 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali C9JCN8.
SMRi C9JCN8. Positions 86-148.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000436647 ; ENSP00000396497 ; ENSG00000075426 .

Organism-specific databases

HGNCi HGNC:3798. FOSL2.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000234334.

Enzyme and pathway databases

SignaLinki C9JCN8.

Miscellaneous databases

ChiTaRSi FOSL2. human.
NextBioi 35485989.

Gene expression databases

ArrayExpressi C9JCN8.
Bgeei C9JCN8.

Family and domain databases

InterProi IPR004827. bZIP.
IPR000837. Leuzip_Fos.
[Graphical view ]
Pfami PF00170. bZIP_1. 1 hit.
[Graphical view ]
PRINTSi PR00042. LEUZIPPRFOS.
SMARTi SM00338. BRLZ. 1 hit.
[Graphical view ]
PROSITEi PS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9JCN8_HUMAN
AccessioniPrimary (citable) accession number: C9JCN8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: June 11, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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