FOSL2

Functionⁱ

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-KW
transcription factor activity, sequence-specific DNA binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

regulation of transcription from RNA polymerase II promoter Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	DNA-bindingSAAS annotation

Molecular function

DNA-bindingSAAS annotation

Enzyme and pathway databases

SignaLinkⁱ	C9JCN8.

SignaLinkⁱ

C9JCN8.

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Fos-related antigen 2Imported
Gene namesⁱ	Name:FOSL2Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 2

Organism-specific databases

HGNCⁱ

HGNC:3798. FOSL2.

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000075426.

OpenTargetsⁱ

ENSG00000075426.

PTM / Processingⁱ

Proteomic databases

EPDⁱ	C9JCN8.
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9JCN8.
PaxDbⁱ	C9JCN8.
PeptideAtlas More...PeptideAtlasⁱ	C9JCN8.
PRIDEⁱ	C9JCN8.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000075426.
ExpressionAtlasⁱ	C9JCN8. baseline and differential.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	C9JCN8.
SMRⁱ	C9JCN8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	85 – 148	BZIP (basic-leucine zipper)InterPro annotationAdd BLAST		64

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	83 – 144	Sequence analysisAdd BLAST		62

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG1414. Eukaryota. ENOG4111CH5. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00730000110541.
HOGENOMⁱ	HOG000234334.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000837. AP-1. IPR004827. bZIP. IPR029814. Fra2.
PANTHERⁱ	PTHR23351. PTHR23351. 1 hit. PTHR23351:SF36. PTHR23351:SF36. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00170. bZIP_1. 1 hit.
PRINTSⁱ	PR00042. LEUZIPPRFOS.
SMARTⁱ	View protein in SMART SM00338. BRLZ. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

C9JCN8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPGSGSAFIP TINAITTSQD LQWMVQPTVI TSMSNPYPRS HPYSPLPGLA 
        60         70         80         90        100
SVPGHMALPR PGVIKTIGTT VGRRRRDEQL SPEEEEKRRI RRERNKLAAA 
       110        120        130        140        150
KCRNRRRELT EKLQAETEEL EEEKSGLQKE IAELQKEKEK LEFMLVAHGP 
       160        170        180        190        200
VCKISPEERR SPPAPGLQPM RSGGGSVGAV VVKQEPLEED SPSSSSAGLD 

KA

Length:202

Mass (Da):22,254

Last modified:November 3, 2009 - v1

Checksum:ⁱ7D32120CEDC46E84

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	202	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC104695 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC104695 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000436647; ENSP00000396497; ENSG00000075426.
UCSC genome browser More...UCSCⁱ	uc061hsd.1. human.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC104695 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC104695 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalⁱ	C9JCN8.
SMRⁱ	C9JCN8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

EPDⁱ	C9JCN8.
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9JCN8.
PaxDbⁱ	C9JCN8.
PeptideAtlas More...PeptideAtlasⁱ	C9JCN8.
PRIDEⁱ	C9JCN8.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000436647; ENSP00000396497; ENSG00000075426.
UCSC genome browser More...UCSCⁱ	uc061hsd.1. human.

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:3798. FOSL2.
Open Targets More...OpenTargetsⁱ	ENSG00000075426.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1414. Eukaryota. ENOG4111CH5. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00730000110541.
HOGENOMⁱ	HOG000234334.

Enzyme and pathway databases

SignaLinkⁱ	C9JCN8.

SignaLinkⁱ

C9JCN8.

Miscellaneous databases

ChiTaRSⁱ	FOSL2. human.

ChiTaRSⁱ

FOSL2. human.

Gene expression databases

Bgeeⁱ	ENSG00000075426.
ExpressionAtlasⁱ	C9JCN8. baseline and differential.

Family and domain databases

InterProⁱ	View protein in InterPro IPR000837. AP-1. IPR004827. bZIP. IPR029814. Fra2.
PANTHERⁱ	PTHR23351. PTHR23351. 1 hit. PTHR23351:SF36. PTHR23351:SF36. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00170. bZIP_1. 1 hit.
PRINTSⁱ	PR00042. LEUZIPPRFOS.
SMARTⁱ	View protein in SMART SM00338. BRLZ. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	C9JCN8_HUMAN
Accessionⁱ	C9JCN8Primary (citable) accession number: C9JCN8
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 3, 2009
	Last sequence update:	November 3, 2009
	Last modified:	July 5, 2017
	This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - C9JCN8 (C9JCN8_HUMAN)

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Fos-related antigen 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ