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Protein
Submitted name:

Cyclic AMP-responsive element-binding protein 1

Gene

CREB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: Ensembl
  2. sequence-specific DNA binding transcription factor activity Source: Ensembl

GO - Biological processi

  1. axonogenesis Source: Ensembl
  2. cellular response to growth factor stimulus Source: Ensembl
  3. cellular response to zinc ion Source: Ensembl
  4. circadian rhythm Source: Ensembl
  5. lactation Source: Ensembl
  6. lung saccule development Source: Ensembl
  7. memory Source: Ensembl
  8. pituitary gland development Source: Ensembl
  9. positive regulation of fat cell differentiation Source: Ensembl
  10. positive regulation of hormone secretion Source: Ensembl
  11. positive regulation of lipid biosynthetic process Source: Ensembl
  12. positive regulation of multicellular organism growth Source: Ensembl
  13. positive regulation of osteoclast differentiation Source: Ensembl
  14. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  15. protein stabilization Source: Ensembl
  16. regulation of cell size Source: Ensembl
  17. response to drug Source: Ensembl
  18. response to glucagon Source: Ensembl
  19. secretory granule organization Source: Ensembl
  20. Type I pneumocyte differentiation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclic AMP-responsive element-binding protein 1Imported
Gene namesi
Name:CREB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:2345. CREB1.

Subcellular locationi

GO - Cellular componenti

  1. nuclear chromatin Source: Ensembl
  2. transcription factor complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiC9JCI4.
ExpressionAtlasiC9JCI4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9JCI4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000008655.

Family and domain databases

InterProiIPR029802. CREB1.
[Graphical view]
PANTHERiPTHR22952:SF104. PTHR22952:SF104. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9JCI4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTMESGAENQ QSGDAAVTEA ENQQMTVQAQ PQIATLAQVS MPAAHATSSA
60 70
PTVTLVQLPN GQTVQVHGVI QAAQPSVIQ
Length:79
Mass (Da):8,125
Last modified:November 3, 2009 - v1
Checksum:iCC26A6374DCF93AF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei79 – 791Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009298 Genomic DNA. No translation available.
AC079767 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000414681; ENSP00000404890; ENSG00000118260.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009298 Genomic DNA. No translation available.
AC079767 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliC9JCI4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000414681; ENSP00000404890; ENSG00000118260.

Organism-specific databases

HGNCiHGNC:2345. CREB1.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000008655.

Miscellaneous databases

ChiTaRSiCREB1. human.
NextBioi35485967.

Gene expression databases

BgeeiC9JCI4.
ExpressionAtlasiC9JCI4. baseline and differential.

Family and domain databases

InterProiIPR029802. CREB1.
[Graphical view]
PANTHERiPTHR22952:SF104. PTHR22952:SF104. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9JCI4_HUMAN
AccessioniPrimary (citable) accession number: C9JCI4
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: January 7, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.