AFF4

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: AF4/FMR2 family member 4Imported
Gene namesⁱ	Name:AFF4Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 5

Organism-specific databases

HGNCⁱ

HGNC:17869. AFF4.

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000072364.

OpenTargetsⁱ

ENSG00000072364.

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9JCE0.
PaxDbⁱ	C9JCE0.
PeptideAtlas More...PeptideAtlasⁱ	C9JCE0.
PRIDEⁱ	C9JCE0.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000072364.
ExpressionAtlasⁱ	C9JCE0. baseline and differential.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000265343.

STRINGⁱ

9606.ENSP00000265343.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	C9JCE0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	ENOG410IGJB. Eukaryota. ENOG410XRXU. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063217.

Family and domain databases

InterProⁱ	View protein in InterPro IPR007797. TF_AF4/FMR2.
PANTHERⁱ	PTHR10528. PTHR10528. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF05110. AF-4. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

C9JCE0-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MNREDRNVLR MKERERRNQE IQQGEDAFPP SSPLFAEPYK VTSKEDKLSS 
        60         70         80         90        100
RIQSMLGNYD EMKDFIGDRS IPKLVAIPKP TVPPSADEKS NPNFFEQRHG 
       110        120        130        140 
GSHQSSKWTP VGPAPSTSQS QKRSSGLQSG HSSQRTSAGS SSGTNSSG

Length:148

Mass (Da):16,307

Last modified:November 3, 2009 - v1

Checksum:ⁱ713959EFDECF55DB

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	148	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC004500 Genomic DNA. No translation available. AC010240 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC004500 Genomic DNA. No translation available.
AC010240 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000421773; ENSP00000395268; ENSG00000072364.
UCSC genome browser More...UCSCⁱ	uc063gxu.1. human.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC004500 Genomic DNA. No translation available. AC010240 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC004500 Genomic DNA. No translation available.
AC010240 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalⁱ	C9JCE0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000265343.

STRINGⁱ

9606.ENSP00000265343.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9JCE0.
PaxDbⁱ	C9JCE0.
PeptideAtlas More...PeptideAtlasⁱ	C9JCE0.
PRIDEⁱ	C9JCE0.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000421773; ENSP00000395268; ENSG00000072364.
UCSC genome browser More...UCSCⁱ	uc063gxu.1. human.

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:17869. AFF4.
Open Targets More...OpenTargetsⁱ	ENSG00000072364.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IGJB. Eukaryota. ENOG410XRXU. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063217.

Miscellaneous databases

ChiTaRSⁱ	AFF4. human.

ChiTaRSⁱ

AFF4. human.

Gene expression databases

Bgeeⁱ	ENSG00000072364.
ExpressionAtlasⁱ	C9JCE0. baseline and differential.

Family and domain databases

InterProⁱ	View protein in InterPro IPR007797. TF_AF4/FMR2.
PANTHERⁱ	PTHR10528. PTHR10528. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF05110. AF-4. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	C9JCE0_HUMAN
Accessionⁱ	C9JCE0Primary (citable) accession number: C9JCE0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 3, 2009
	Last sequence update:	November 3, 2009
	Last modified:	March 15, 2017
	This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - C9JCE0 (C9JCE0_HUMAN)

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AF4/FMR2 family member 4

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ