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Protein
Submitted name:

Interferon regulatory factor 5

Gene

IRF5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 5Imported
Gene namesi
Name:IRF5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000128604.18
HGNCiHGNC:6120 IRF5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000128604

PTM / Processingi

Proteomic databases

MaxQBiC9JB67
PeptideAtlasiC9JB67

Expressioni

Gene expression databases

BgeeiENSG00000128604
ExpressionAtlasiC9JB67 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9JB67
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 59IRF tryptophan pentad repeatInterPro annotationAdd BLAST46

Sequence similaritiesi

Belongs to the IRF family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IFCV Eukaryota
ENOG410XRXT LUCA
GeneTreeiENSGT00760000119093

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001346 Interferon_reg_fact_DNA-bd_dom
IPR029838 IRF5
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR11949 PTHR11949, 1 hit
PTHR11949:SF10 PTHR11949:SF10, 1 hit
PfamiView protein in Pfam
PF00605 IRF, 1 hit
PRINTSiPR00267 INTFRNREGFCT
SMARTiView protein in SMART
SM00348 IRF, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS51507 IRF_2, 1 hit

Sequencei

Sequence statusi: Fragment.

C9JB67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQSIPVAPT PPRRVRLKPW LVAQVNSCQY PGLQWVNGEK KLFCIPWRHA

TRHGPSQDG
Length:59
Mass (Da):6,748
Last modified:November 3, 2009 - v1
Checksum:i6358B52618DF6A8D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei59Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025594 Genomic DNA No translation available.
KF459647 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000467002; ENSP00000417454; ENSG00000128604
UCSCiuc064hwk.1 human

Similar proteinsi

Entry informationi

Entry nameiC9JB67_HUMAN
AccessioniPrimary (citable) accession number: C9JB67
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: March 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health