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C9J9W2

- C9J9W2_HUMAN

UniProt

C9J9W2 - C9J9W2_HUMAN

Protein
Submitted name:

LIM and SH3 domain protein 1

Gene

LASP1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ion transmembrane transporter activity Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    LIM and SH3 domain protein 1Imported
    Gene namesi
    Name:LASP1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:6513. LASP1.

    Subcellular locationi

    GO - Cellular componenti

    1. cortical actin cytoskeleton Source: Ensembl
    2. focal adhesion Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiC9J9W2.

    Expressioni

    Gene expression databases

    ArrayExpressiC9J9W2.
    BgeeiC9J9W2.

    Structurei

    3D structure databases

    ProteinModelPortaliC9J9W2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000006616.

    Family and domain databases

    InterProiIPR000900. Nebulin_repeat.
    [Graphical view]
    PfamiPF00880. Nebulin. 2 hits.
    [Graphical view]
    SMARTiSM00227. NEBU. 2 hits.
    [Graphical view]
    PROSITEiPS51216. NEBULIN. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    C9J9W2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTLNMKNYKG YEKKPYCNAH YPKQSFTMVA DTPENLRLKQ QSELQSQVRY    50
    KEEFEKNKGK GFSVVADTPE LQRIKKTQDQ ISNIKYHEEF EKSRMGPSGG 100
    EGMEPERRDS QDGSSYRRPL EQQQPHHIPT SAPVYQQPQQ QPVAQSYGGY 150
    KEPAAPVSIQ RSAPGG 166
    Length:166
    Mass (Da):18,980
    Last modified:November 3, 2009 - v1
    Checksum:i2A377D940BC5F061
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei166 – 1661Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC006441 Genomic DNA. No translation available.
    AC110749 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000419929; ENSP00000391897; ENSG00000002834.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC006441 Genomic DNA. No translation available.
    AC110749 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali C9J9W2.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi C9J9W2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000419929 ; ENSP00000391897 ; ENSG00000002834 .

    Organism-specific databases

    HGNCi HGNC:6513. LASP1.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000006616.

    Miscellaneous databases

    ChiTaRSi LASP1. human.
    NextBioi 35485641.

    Gene expression databases

    ArrayExpressi C9J9W2.
    Bgeei C9J9W2.

    Family and domain databases

    InterProi IPR000900. Nebulin_repeat.
    [Graphical view ]
    Pfami PF00880. Nebulin. 2 hits.
    [Graphical view ]
    SMARTi SM00227. NEBU. 2 hits.
    [Graphical view ]
    PROSITEi PS51216. NEBULIN. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
      Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
      , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
      Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."
      Yu L.R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.
      J. Proteome Res. 6:4150-4162(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    5. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    6. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
      Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    9. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9J9W2_HUMAN
    AccessioniPrimary (citable) accession number: C9J9W2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3