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Protein
Submitted name:

Interleukin-1 receptor accessory protein

Gene

IL1RAP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin-1 receptor accessory proteinImported
Gene namesi
Name:IL1RAPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:5995. IL1RAP.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000196083.

PTM / Processingi

Proteomic databases

MaxQBiC9J9W1.
PaxDbiC9J9W1.
PeptideAtlasiC9J9W1.

Expressioni

Gene expression databases

BgeeiENSG00000196083.
ExpressionAtlasiC9J9W1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000314807.

Structurei

3D structure databases

ProteinModelPortaliC9J9W1.
SMRiC9J9W1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 89Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST89
Domaini101 – 207Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST107

Phylogenomic databases

eggNOGiENOG410IEPH. Eukaryota.
ENOG410ZRCQ. LUCA.
GeneTreeiENSGT00760000119071.
HOGENOMiHOG000120108.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR015621. IL-1_rcpt_fam.
IPR004074. IL-1_rcpt_I/II-typ.
PANTHERiPTHR11890. PTHR11890. 1 hit.
PRINTSiPR01536. INTRLKN1R12F.
SMARTiView protein in SMART
SM00409. IG. 2 hits.
SUPFAMiSSF48726. SSF48726. 2 hits.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 2 hits.

Sequencei

Sequence statusi: Complete.

C9J9W1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLPVHKLYI EYGIQRITCP NVDGYFPSSV KPTITWYMGC YKIQNFNNVI
60 70 80 90 100
PEGMNLSFLI ALISNNGNYT CVVTYPENGR TFHLTRTLTV KVVGSPKNAV
110 120 130 140 150
PPVIHSPNDH VVYEKEPGEE LLIPCTVYFS FLMDSRNEVW WTIDGKKPDD
160 170 180 190 200
ITIDVTINES ISHSRTEDET RTQILSIKKV TSEDLKRSYV CHARSAKGEV
210
AKAAKVKQKG NRCGQ
Length:215
Mass (Da):24,329
Last modified:November 3, 2009 - v1
Checksum:i439EAE1EACD0E2DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008249 Genomic DNA. No translation available.
AC108747 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000434491; ENSP00000391899; ENSG00000196083.
UCSCiuc062rjx.1. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiC9J9W1_HUMAN
AccessioniPrimary (citable) accession number: C9J9W1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: March 15, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported