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Protein

Nucleoside diphosphate kinase

Gene

NME6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside diphosphate kinaseUniRule annotation (EC:2.7.4.6UniRule annotation)
Gene namesi
Name:NME6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000172113.8.
HGNCiHGNC:20567. NME6.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172113.

PTM / Processingi

Proteomic databases

MaxQBiC9J9V6.
PaxDbiC9J9V6.
PeptideAtlasiC9J9V6.
PRIDEiC9J9V6.

Expressioni

Gene expression databases

BgeeiENSG00000172113.
ExpressionAtlasiC9J9V6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9J9V6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 147NDKInterPro annotationAdd BLAST135

Sequence similaritiesi

Belongs to the NDK family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0888. Eukaryota.
COG0105. LUCA.
GeneTreeiENSGT00760000119146.
HOGENOMiHOG000224565.

Family and domain databases

Gene3Di3.30.70.141. 1 hit.
InterProiView protein in InterPro
IPR034907. NDK-like_dom.
IPR001564. Nucleoside_diP_kinase.
IPR023005. Nucleoside_diP_kinase_AS.
PfamiView protein in Pfam
PF00334. NDK. 1 hit.
PRINTSiPR01243. NUCDPKINASE.
SMARTiView protein in SMART
SM00562. NDK. 1 hit.
SUPFAMiSSF54919. SSF54919. 1 hit.
PROSITEiView protein in PROSITE
PS00469. NDP_KINASES. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9J9V6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASILRSPQA LQLTLALIKP DAVAHPLILE AVHQQILSNK FLIVRMRELL
60 70 80 90 100
WRKEDCQRFY REHEGRFFYQ RLVEFMASGP IRAYILAHKD AIQLWRTLMG
110 120 130 140 150
PTRVFRARHV APDSIRGSFG LTDTRNTTHG SDSVVSASRE IAAFFPDFSE
160 170
QRWYEEEEPQ LRCGPVCYSP EGGV
Length:174
Mass (Da):20,061
Last modified:November 3, 2009 - v1
Checksum:iABE455F343AB3E16
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei174Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105267 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000425930; ENSP00000411116; ENSG00000172113.
UCSCiuc062jgl.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9J9V6_HUMAN
AccessioniPrimary (citable) accession number: C9J9V6
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 27, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported