C9J9D8 (C9J9D8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aminoacylase-1 Ensembl ENSP00000417618

Gene names

Name:

ACY1 Ensembl ENSP00000417618

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000417618

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000417618

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	aminoacylase activity Inferred from electronic annotation. Source: InterPro metallopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C9J9D8 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 68C1E4266A8CBE70	FASTA	336	37,597
	10 20 30 40 50 60 MTSKGPEEEH PSVTLFRQYL RIRTVQPKPD YGAAVAFFEE TARQLGLGCQ KVEVAPGYVV 70 80 90 100 110 120 TVLTWPGTNP TLSSILLNSH TDVVPVFKEH WSHDPFEAFK DSEGIANPTD AFTVFYSERS 130 140 150 160 170 180 PWWVRVTSTG RPGHASRFME DTAAEKLHKV VNSILAFREK EWQRLQSNPH LKEGSVTSVN 190 200 210 220 230 240 LTKLEGGVAY NVIPATMSAS FDFRVAPDVD FKAFEEQLQS WCQAAGEGVT LEFAQKWMHP 250 260 270 280 290 300 QVTPTDDSNP WWAAFSRVCK DMNLTLEPEI MPAATDNRYI RAVGVPALGF SPMNRTPVLL 310 320 330 HDHDERLHEA VFLRGVDIYT RLLPALASVP ALPSDS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC115284 Genomic DNA. No translation available.
IPI	IPI00791053.
RefSeq	NP_001185825.1. NM_001198896.1.
UniGene	Hs.334707.
3D structure databases
ProteinModelPortal	C9J9D8.
SMR	C9J9D8. Positions 7-104, 249-336.
ModBase	Search...
Protocols and materials databases
DNASU	95.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000494103; ENSP00000417618; ENSG00000243989.
GeneID	95.
KEGG	hsa:95.
UCSC	uc021wzc.1. human.
Organism-specific databases
CTD	95.
HGNC	HGNC:177. ACY1.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000021196.
KO	K14677.
Gene expression databases
ArrayExpress	C9J9D8.
Bgee	C9J9D8.
Family and domain databases
Gene3D	3.30.70.360. 1 hit.
InterPro	IPR001261. ArgE/DapE_CS. IPR010159. N-acyl_aa_amidohydrolase. IPR002933. Peptidase_M20. IPR011650. Peptidase_M20_dimer. [Graphical view]
Pfam	PF07687. M20_dimer. 1 hit. PF01546. Peptidase_M20. 1 hit. [Graphical view]
SUPFAM	SSF55031. Peptidase_M20_dimer. 1 hit.
TIGRFAMs	TIGR01880. Ac-peptdase-euk. 1 hit.
PROSITE	PS00758. ARGE_DAPE_CPG2_1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ACY1. human.
GenomeRNAi	95.
NextBio	361.

Entry information

Entry name

C9J9D8_HUMAN

Accession

Primary (citable) accession number: C9J9D8

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 29, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.