PIM2

Functionⁱ

GO - Molecular functionⁱ

ATP binding Source: InterPro
protein kinase activity Source: InterPro

Enzyme and pathway databases

SignaLinkⁱ	C9J8V9.

SignaLinkⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Serine/threonine-protein kinase pim-2Imported
Gene namesⁱ	Name:PIM2Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome X

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000102096.9.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:8987. PIM2.

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000102096.

OpenTargetsⁱ

ENSG00000102096.

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9J8V9.
PaxDbⁱ	C9J8V9.
PeptideAtlas More...PeptideAtlasⁱ	C9J8V9.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000102096.
ExpressionAtlasⁱ	C9J8V9. baseline and differential.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	C9J8V9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1 – 145	Protein kinaseInterPro annotationAdd BLAST		145

Phylogenomic databases

eggNOGⁱ	KOG0583. Eukaryota. COG0515. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119045.
HOGENOMⁱ	HOG000231357.

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_dom. IPR008271. Ser/Thr_kinase_AS.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069. Pkinase. 1 hit.
SMARTⁱ	View protein in SMART SM00220. S_TKc. 1 hit.
SUPFAMⁱ	SSF56112. SSF56112. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

C9J8V9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLVLERPLPA QDLFDYITEK GPLGEGPSRC FFGQVVAAIQ HCHSRGVVHR 
        60         70         80         90        100
DIKDENILID LRRGCAKLID FGSGALLHDE PYTDFDGTRV YSPPEWISRH 
       110        120        130        140 
QYHALPATVW SLGILLYDMV CGDIPFERDQ EILEAELHFP AHVSP

Length:145

Mass (Da):16,410

Last modified:November 3, 2009 - v1

Checksum:ⁱ76D1DE1AC4643513

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	145	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC233300 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC233300 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000442430; ENSP00000410960; ENSG00000102096.
UCSC genome browser More...UCSCⁱ	uc064zci.1. human.

Similar proteinsⁱ

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
C9J8V9	G3R726 UPI00029DBE2D	Gorilla gorilla gorilla (Western lowland gorilla) Homo sapiens (Human)	374	UniRef100_G3R726	Cluster: Pim-2 proto-oncogene, serine/threonine kinase	3

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
C9J8V9	F7CKA2 UPI0001797D95 Q6Q2K5 UPI00071A400D UPI0007196F20 G1TA52 G3R726 UPI00029DBE2D G1PD38 UPI00015189B8 +3	Equus caballus (Horse) Canis lupus familiaris (Dog) (Canis familiaris) Equus asinus (Donkey) (Equus africanus asinus) Ceratotherium simum simum (southern white rhinoceros) Oryctolagus cuniculus (Rabbit) Gorilla gorilla gorilla (Western lowland gorilla) Homo sapiens (Human) Myotis lucifugus (Little brown bat) Myotis brandtii (Brandt's bat) Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)	311	UniRef90_F7CKA2	Cluster: Pim-2 proto-oncogene, serine/threonine kinase	14

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
C9J8V9	Q62070 A0A1U7RBA8 UPI000359C7F7 Q62070-2 Q62070-3 F6WGR1 Q99PC4 Q8R1Z0 UPI0003EC5E69 UPI00042BC44E +134	Mus musculus (Mouse) Mesocricetus auratus (Golden hamster) Myotis davidii (David's myotis) Panthera tigris altaica (Siberian tiger) Acinonyx jubatus (Cheetah) Saimiri boliviensis boliviensis (Bolivian squirrel monkey) Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) Colobus angolensis palliatus (Peters' Angolan colobus) Condylura cristata (Star-nosed mole) Equus przewalskii (Przewalski's horse) (Equus caballus przewalskii) And more	370	UniRef50_Q62070	Cluster: Serine/threonine-protein kinase pim-2	145

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC233300 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC233300 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalⁱ	C9J8V9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9J8V9.
PaxDbⁱ	C9J8V9.
PeptideAtlas More...PeptideAtlasⁱ	C9J8V9.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000442430; ENSP00000410960; ENSG00000102096.
UCSC genome browser More...UCSCⁱ	uc064zci.1. human.

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000102096.9.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:8987. PIM2.
Open Targets More...OpenTargetsⁱ	ENSG00000102096.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0583. Eukaryota. COG0515. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119045.
HOGENOMⁱ	HOG000231357.

Enzyme and pathway databases

SignaLinkⁱ	C9J8V9.

SignaLinkⁱ

C9J8V9.

Miscellaneous databases

ChiTaRSⁱ	PIM2. human.

ChiTaRSⁱ

PIM2. human.

Gene expression databases

Bgeeⁱ	ENSG00000102096.
ExpressionAtlasⁱ	C9J8V9. baseline and differential.

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_dom. IPR008271. Ser/Thr_kinase_AS.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069. Pkinase. 1 hit.
SMARTⁱ	View protein in SMART SM00220. S_TKc. 1 hit.
SUPFAMⁱ	SSF56112. SSF56112. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	C9J8V9_HUMAN
Accessionⁱ	C9J8V9Primary (citable) accession number: C9J8V9
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 3, 2009
	Last sequence update:	November 3, 2009
	Last modified:	September 27, 2017
	This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - C9J8V9 (C9J8V9_HUMAN)

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Serine/threonine-protein kinase pim-2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ