PIM2

Functionⁱ

GO - Molecular functionⁱ

ATP binding Source: InterPro
protein kinase activity Source: InterPro

View the complete GO annotation on QuickGO ...

Enzyme and pathway databases

SignaLinkⁱ	C9J8V9

SignaLinkⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Serine/threonine-protein kinase pim-2Imported
Gene namesⁱ	Name:PIM2Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome X

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000102096.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:8987 PIM2

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000102096

OpenTargetsⁱ

ENSG00000102096

PTM / Processingⁱ

Proteomic databases

EPDⁱ	C9J8V9
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9J8V9
PeptideAtlas More...PeptideAtlasⁱ	C9J8V9
PRIDEⁱ	C9J8V9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000102096
ExpressionAtlasⁱ	C9J8V9 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	C9J8V9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1 – 145	Protein kinaseInterPro annotationAdd BLAST		145

Phylogenomic databases

eggNOGⁱ	KOG0583 Eukaryota COG0515 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119045
HOGENOMⁱ	HOG000231357

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009 Kinase-like_dom_sf IPR000719 Prot_kinase_dom IPR008271 Ser/Thr_kinase_AS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069 Pkinase, 1 hit
SMARTⁱ	View protein in SMART SM00220 S_TKc, 1 hit
SUPFAMⁱ	SSF56112 SSF56112, 1 hit
PROSITEⁱ	View protein in PROSITE PS50011 PROTEIN_KINASE_DOM, 1 hit PS00108 PROTEIN_KINASE_ST, 1 hit

Sequenceⁱ

Sequence statusⁱ: Fragment.

C9J8V9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLVLERPLPA QDLFDYITEK GPLGEGPSRC FFGQVVAAIQ HCHSRGVVHR 
        60         70         80         90        100
DIKDENILID LRRGCAKLID FGSGALLHDE PYTDFDGTRV YSPPEWISRH 
       110        120        130        140 
QYHALPATVW SLGILLYDMV CGDIPFERDQ EILEAELHFP AHVSP

Length:145

Mass (Da):16,410

Last modified:November 3, 2009 - v1

Checksum:ⁱ76D1DE1AC4643513

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	145	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC233300 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC233300 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000442430; ENSP00000410960; ENSG00000102096
UCSC genome browser More...UCSCⁱ	uc064zci.1 human

Protein	Similar proteins		Species	Score	Length
C9J8V9	Serine/threonine-protein kinase pim-2	)	HUMAN		311
PIM2 isoform 2 (Fragment)		PONAB		145
Pim-2 oncogene, isoform CRA_a		HUMAN		311
UPI0000DBE12D		HUMAN		312

Protein	Similar proteins		Species	Score	Length
C9J8V9	Serine/threonine-protein kinase pim-2	)	HUMAN		311
PIM2 isoform 2 (Fragment)		PONAB		145
UPI0006252AAC		AOTNA		319
Pim-2 proto-oncogene, serine/threonine kinase		GORGO		311
Pim-2 proto-oncogene, serine/threonine kinase		SAIBB		305
+6

Protein	Similar proteins		Species	Score	Length
C9J8V9	Serine/threonine-protein kinase pim-2	)	HUMAN		311
PIM2 isoform 2 (Fragment)		PONAB		145
UPI0006252AAC		AOTNA		319
Pim-2 proto-oncogene, serine/threonine kinase		GORGO		311
Pim-2 proto-oncogene, serine/threonine kinase		SAIBB		305
+36

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC233300 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC233300 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	C9J8V9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

EPDⁱ	C9J8V9
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	C9J8V9
PeptideAtlas More...PeptideAtlasⁱ	C9J8V9
PRIDEⁱ	C9J8V9

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000442430; ENSP00000410960; ENSG00000102096
UCSC genome browser More...UCSCⁱ	uc064zci.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000102096.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:8987 PIM2
Open Targets More...OpenTargetsⁱ	ENSG00000102096
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0583 Eukaryota COG0515 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119045
HOGENOMⁱ	HOG000231357

Enzyme and pathway databases

SignaLinkⁱ	C9J8V9

SignaLinkⁱ

C9J8V9

Miscellaneous databases

ChiTaRSⁱ	PIM2 human

ChiTaRSⁱ

PIM2 human

Gene expression databases

Bgeeⁱ	ENSG00000102096
ExpressionAtlasⁱ	C9J8V9 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009 Kinase-like_dom_sf IPR000719 Prot_kinase_dom IPR008271 Ser/Thr_kinase_AS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069 Pkinase, 1 hit
SMARTⁱ	View protein in SMART SM00220 S_TKc, 1 hit
SUPFAMⁱ	SSF56112 SSF56112, 1 hit
PROSITEⁱ	View protein in PROSITE PS50011 PROTEIN_KINASE_DOM, 1 hit PS00108 PROTEIN_KINASE_ST, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	C9J8V9_HUMAN
Accessionⁱ	C9J8V9Primary (citable) accession number: C9J8V9
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 3, 2009
	Last sequence update:	November 3, 2009
	Last modified:	May 23, 2018
	This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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UniParc

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Supporting data

UniProtKB - C9J8V9 (C9J8V9_HUMAN)

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Serine/threonine-protein kinase pim-2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ