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UniProtKB - C9J6P4 (C9J6P4_HUMAN)

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Protein
Submitted name:

Zinc finger CCCH-type antiviral protein 1

Gene

ZC3HAV1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri76 – 113C3H1-typePROSITE-ProRule annotationAdd BLAST38
Zinc fingeri173 – 194C3H1-typePROSITE-ProRule annotationAdd BLAST22
Zinc fingeri630 – 656C3H1-typePROSITE-ProRule annotationAdd BLAST27

GO - Molecular functioni

Complete GO annotation...

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger CCCH-type antiviral protein 1Imported
Gene namesi
Name:ZC3HAV1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:23721. ZC3HAV1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000105939.

PTM / Processingi

Proteomic databases

EPDiC9J6P4.
MaxQBiC9J6P4.
PaxDbiC9J6P4.
PeptideAtlasiC9J6P4.
PRIDEiC9J6P4.

Expressioni

Gene expression databases

BgeeiENSG00000105939.
ExpressionAtlasiC9J6P4. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiC9J6P4. 5 interactors.
STRINGi9606.ENSP00000242351.

Structurei

3D structure databases

ProteinModelPortaliC9J6P4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 113C3H1-typeInterPro annotationAdd BLAST38
Domaini173 – 194C3H1-typeInterPro annotationAdd BLAST22
Domaini630 – 656C3H1-typeInterPro annotationAdd BLAST27
Domaini716 – 803WWEInterPro annotationAdd BLAST88
Domaini838 – 1024PARP catalyticInterPro annotationAdd BLAST187

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri76 – 113C3H1-typePROSITE-ProRule annotationAdd BLAST38
Zinc fingeri173 – 194C3H1-typePROSITE-ProRule annotationAdd BLAST22
Zinc fingeri630 – 656C3H1-typePROSITE-ProRule annotationAdd BLAST27

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IEI4. Eukaryota.
ENOG410ZFB8. LUCA.
GeneTreeiENSGT00760000119084.
HOGENOMiHOG000236279.
OMAiSHNLMDR.
OrthoDBiEOG091G14UY.
PhylomeDBiC9J6P4.

Family and domain databases

InterProiView protein in InterPro
IPR012317. Poly(ADP-ribose)pol_cat_dom.
IPR004170. WWE-dom.
IPR000571. Znf_CCCH.
PfamiView protein in Pfam
PF00644. PARP. 1 hit.
PF02825. WWE. 1 hit.
PROSITEiView protein in PROSITE
PS51059. PARP_CATALYTIC. 1 hit.
PS50918. WWE. 1 hit.
PS50103. ZF_C3H1. 3 hits.

Sequencei

Sequence statusi: Complete.

C9J6P4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADPEVCCFI TKILCAHGGR MALDALLQEI ALSEPQLCEV LQVAGPDRFV 
        60         70         80         90        100
VLETGGEAGI TRSVVATTRA RVCRRKYCQR PCDNLHLCKL NLLGRCNYSQ 
       110        120        130        140        150
SERNLCKYSH EVLSEENFKV LKNHELSGLN KEELAVLLLQ SDPFFMPEIC 
       160        170        180        190        200
KSYKGEGRQQ ICNQQPPCSR LHICDHFTRG NCRFPNCLRS HNLMDRKVLA 
       210        220        230        240        250
IMREHGLNPD VVQNIQDICN SKHMQKNPPG PRAPSSHRRN MAYRARSKSR 
       260        270        280        290        300
DRFFQGSQEF LASASASAER SCTPSPDQIS HRASLEDAPV DDLTRKFTYL 
       310        320        330        340        350
GSQDRARPPS GSSKATDLGG TSQAGTSQRF LENGSQEDLL HGNPGSTYLA 
       360        370        380        390        400
SNSTSAPNWK SLTSWTNDQG ARRKTVFSPT LPAARSSLGS LQTPEAVTTR 
       410        420        430        440        450
KGTGLLSSDY RIINGKSGTQ DIQPGPLFNN NADGVATDIT STRSLNYKST 
       460        470        480        490        500
SSGHREISSP RIQDAGPASR DVQATGRIAD DADPRVALVN GKYKGKTLWA 
       510        520        530        540        550
STFVHDIPNG SSQVVDKTTD VEKTGATGFG LTMAVKAEKD MLRTGSQSLR 
       560        570        580        590        600
NLVPTTPGES TAPAQVSTLP QSPAALSSSN RAAVWGAQGQ NCTQVPVSSA 
       610        620        630        640        650
SELTRKTTGS AQYSLSDVTS TTSSRVDDHD SEEICLDHLC KGCPLNGSCS 
       660        670        680        690        700
KVHFHLPYRW QMLIGKTWTD FEHMETIEKG YCNPGIHLCS VGSYTINFRV 
       710        720        730        740        750
MSCDSFPIRR LSTPSSVTKP ANSVFTTKWI WYWKNESGTW IQYGEEKDKR 
       760        770        780        790        800
KNSNVDSSYL ESLYQSCPRG VVPFQAGSRN YELSFQGMIQ TNIASKTQKD 
       810        820        830        840        850
VIRRPTFVPQ WYVQQMKRGP DHQPAKTSSV SLTATFRPQE DFCFLSSKKY 
       860        870        880        890        900
KLSEIHHLHP EYVRVSEHFK ASMKNFKIEK IKKIENSELL DKFTWKKSQM 
       910        920        930        940        950
KEEGKLLFYA TSRAYVESIC SNNFDSFLHE THENKYGKGI YFAKDAIYSH 
       960        970        980        990       1000
KNCPYDAKNV VMFVAQVLVG KFTEGNITYT SPPPQFDSCV DTRSNPSVFV 
      1010       1020 
IFQKDQVYPQ YVIEYTEDKA CVIS
Length:1,024
Mass (Da):114,085
Last modified:November 3, 2009 - v1
Checksum:iFD15D0C32EA69B17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018644 Genomic DNA. No translation available.
AC083868 Genomic DNA. No translation available.
RefSeqiXP_005250558.1. XM_005250501.2.
UniGeneiHs.133512.

Genome annotation databases

EnsembliENST00000464606; ENSP00000418385; ENSG00000105939.
GeneIDi56829.
UCSCiuc064ikv.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018644 Genomic DNA. No translation available.
AC083868 Genomic DNA. No translation available.
RefSeqiXP_005250558.1. XM_005250501.2.
UniGeneiHs.133512.

3D structure databases

ProteinModelPortaliC9J6P4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiC9J6P4. 5 interactors.
STRINGi9606.ENSP00000242351.

Proteomic databases

EPDiC9J6P4.
MaxQBiC9J6P4.
PaxDbiC9J6P4.
PeptideAtlasiC9J6P4.
PRIDEiC9J6P4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000464606; ENSP00000418385; ENSG00000105939.
GeneIDi56829.
UCSCiuc064ikv.1. human.

Organism-specific databases

CTDi56829.
HGNCiHGNC:23721. ZC3HAV1.
OpenTargetsiENSG00000105939.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IEI4. Eukaryota.
ENOG410ZFB8. LUCA.
GeneTreeiENSGT00760000119084.
HOGENOMiHOG000236279.
OMAiSHNLMDR.
OrthoDBiEOG091G14UY.
PhylomeDBiC9J6P4.

Miscellaneous databases

ChiTaRSiZC3HAV1. human.
GenomeRNAii56829.

Gene expression databases

BgeeiENSG00000105939.
ExpressionAtlasiC9J6P4. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR012317. Poly(ADP-ribose)pol_cat_dom.
IPR004170. WWE-dom.
IPR000571. Znf_CCCH.
PfamiView protein in Pfam
PF00644. PARP. 1 hit.
PF02825. WWE. 1 hit.
PROSITEiView protein in PROSITE
PS51059. PARP_CATALYTIC. 1 hit.
PS50918. WWE. 1 hit.
PS50103. ZF_C3H1. 3 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiC9J6P4_HUMAN
AccessioniPrimary (citable) accession number: C9J6P4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 10, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.