C9J6I6 (C9J6I6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aminoacylase-1 Ensembl ENSP00000417056

Gene names

Name:

ACY1 Ensembl ENSP00000417056

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000417056

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	373 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000417056

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	aminoacylase activity Inferred from electronic annotation. Source: InterPro metallopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C9J6I6 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 343DC089BDBDC22F	FASTA	373	42,195
	10 20 30 40 50 60 MTSKGPEEEH PSVTLFRQYL RIRTVQPKPD YGTNPTLSSI LLNSHTDVVP VFKEHWSHDP 70 80 90 100 110 120 FEAFKDSEGY IYARGAQDMK CVSIQYLEAV RRLKVEGHRF PRTIHMTFVP DEEVGGHQGM 130 140 150 160 170 180 ELFVQRPEFH ALRAGFALDE GIANPTDAFT VFYSERSPWW VRVTSTGRPG HASRFMEDTA 190 200 210 220 230 240 AEKLHKVVNS ILAFREKEWQ RLQSNPHLKE GSVTSVNLTK LEGGVAYNVI PATMSASFDF 250 260 270 280 290 300 RVAPDVDFKA FEEQLQSWCQ AAGEGVTLEF AQKWMHPQVT PTDDSNPWWA AFSRVCKDMN 310 320 330 340 350 360 LTLEPEIMPA ATDNRYIRAV GVPALGFSPM NRTPVLLHDH DERLHEAVFL RGVDIYTRLL 370 PALASVPALP SDS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence, annotation and analysis of human chromosome 3." Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A. Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC115284 Genomic DNA. No translation available.
IPI	IPI00788719.
RefSeq	NP_001185827.1. NM_001198898.1.
UniGene	Hs.334707.
3D structure databases
ProteinModelPortal	C9J6I6.
SMR	C9J6I6. Positions 7-373.
ModBase	Search...
Proteomic databases
PRIDE	C9J6I6.
Protocols and materials databases
DNASU	95.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000476351; ENSP00000417056; ENSG00000243989.
GeneID	95.
KEGG	hsa:95.
UCSC	uc021wzb.1. human.
Organism-specific databases
CTD	95.
HGNC	HGNC:177. ACY1.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000021196.
KO	K14677.
Gene expression databases
ArrayExpress	C9J6I6.
Bgee	C9J6I6.
Family and domain databases
Gene3D	3.30.70.360. 1 hit.
InterPro	IPR001261. ArgE/DapE_CS. IPR010159. N-acyl_aa_amidohydrolase. IPR002933. Peptidase_M20. IPR011650. Peptidase_M20_dimer. [Graphical view]
Pfam	PF07687. M20_dimer. 1 hit. PF01546. Peptidase_M20. 1 hit. [Graphical view]
PIRSF	PIRSF036696. ACY-1. 1 hit.
SUPFAM	SSF55031. Peptidase_M20_dimer. 1 hit.
TIGRFAMs	TIGR01880. Ac-peptdase-euk. 1 hit.
PROSITE	PS00758. ARGE_DAPE_CPG2_1. 1 hit. PS00759. ARGE_DAPE_CPG2_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ACY1. human.
GenomeRNAi	95.
NextBio	361.

Entry information

Entry name

C9J6I6_HUMAN

Accession

Primary (citable) accession number: C9J6I6

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	May 29, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.