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Protein
Submitted name:

Rho guanine nucleotide exchange factor 3

Gene

ARHGEF3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 3Imported
Gene namesi
Name:ARHGEF3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000163947.11.
HGNCiHGNC:683. ARHGEF3.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000163947.

PTM / Processingi

Proteomic databases

MaxQBiC9J609.
PaxDbiC9J609.
PeptideAtlasiC9J609.
PRIDEiC9J609.

Expressioni

Gene expression databases

BgeeiENSG00000163947.
ExpressionAtlasiC9J609. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9J609.
SMRiC9J609.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini123 – 184DHInterPro annotationAdd BLAST62

Phylogenomic databases

eggNOGiKOG4305. Eukaryota.
COG5422. LUCA.
GeneTreeiENSGT00760000119193.

Family and domain databases

InterProiView protein in InterPro
IPR000219. DH-domain.
PfamiView protein in Pfam
PF00621. RhoGEF. 1 hit.
SUPFAMiSSF48065. SSF48065. 1 hit.
PROSITEiView protein in PROSITE
PS50010. DH_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9J609-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPSPKAWNF RGRKRKQSTQ DEDAVSLCSL DISEPSNKRV KPLSRVTSLA
60 70 80 90 100
NLIPPVKATP LKRFSQTLQR SISFRSESRP DILAPRPWSR NAAPSSTKRR
110 120 130 140 150
DSKLWSETFD VCVNQMLTSK EIKRQEAIFE LSQGEEDLIE DLKLAKKAYH
160 170 180
DPMLKLSIMT EQELNQIFGT LDSLIPLHEE LLSQ
Length:184
Mass (Da):21,082
Last modified:November 3, 2009 - v1
Checksum:iEA985C05CE09BBD3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei184Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097358 Genomic DNA. No translation available.
AC099327 Genomic DNA. No translation available.
AC099559 Genomic DNA. No translation available.
AC099781 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000468727; ENSP00000417087; ENSG00000163947.
UCSCiuc062kvu.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9J609_HUMAN
AccessioniPrimary (citable) accession number: C9J609
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 27, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported