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C9J5P8

- C9J5P8_HUMAN

UniProt

C9J5P8 - C9J5P8_HUMAN

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Protein
Submitted name:

Sodium- and chloride-dependent GABA transporter 1

Gene

SLC6A1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. gamma-aminobutyric acid:sodium symporter activity Source: Ensembl

GO - Biological processi

  1. gamma-aminobutyric acid import Source: Ensembl
  2. learning Source: Ensembl
  3. negative regulation of synaptic transmission, GABAergic Source: Ensembl
  4. positive regulation of gamma-aminobutyric acid secretion Source: Ensembl
  5. protein homooligomerization Source: Ensembl
  6. response to calcium ion Source: Ensembl
  7. response to cocaine Source: Ensembl
  8. response to estradiol Source: Ensembl
  9. response to lead ion Source: Ensembl
  10. response to purine-containing compound Source: Ensembl
  11. response to sucrose Source: Ensembl
  12. response to toxic substance Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sodium- and chloride-dependent GABA transporter 1Imported
Gene namesi
Name:SLC6A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:11042. SLC6A1.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: Ensembl
  2. cell surface Source: Ensembl
  3. plasma membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiC9J5P8.
ExpressionAtlasiC9J5P8. baseline and differential.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118857.

Sequencei

Sequence statusi: Fragment.

C9J5P8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30 
MATNGSKVAD GQISTEVSEA PVANDKPKTL VVKVQKKAA
Length:39
Mass (Da):4,012
Last modified:October 29, 2014 - v3
Checksum:iAE933A7D170A9FD6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei39 – 391Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC024910 Genomic DNA. No translation available.
KF457578 Genomic DNA. No translation available.
KF457580 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000425938; ENSP00000411689; ENSG00000157103.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC024910 Genomic DNA. No translation available.
KF457578 Genomic DNA. No translation available.
KF457580 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000425938 ; ENSP00000411689 ; ENSG00000157103 .

Organism-specific databases

HGNCi HGNC:11042. SLC6A1.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118857.

Miscellaneous databases

ChiTaRSi SLC6A1. human.
NextBioi 35485095.

Gene expression databases

Bgeei C9J5P8.
ExpressionAtlasi C9J5P8. baseline and differential.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9J5P8_HUMAN
AccessioniPrimary (citable) accession number: C9J5P8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 29, 2014
Last modified: November 26, 2014
This is version 34 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3