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Submitted name:

Sodium- and chloride-dependent GABA transporter 1



Homo sapiens (Human)
Unreviewed - Annotation score: 2 out of 5- Protein predictedi


GO - Molecular functioni

  1. gamma-aminobutyric acid:sodium symporter activity Source: Ensembl

GO - Biological processi

  1. gamma-aminobutyric acid import Source: Ensembl
  2. learning Source: Ensembl
  3. negative regulation of synaptic transmission, GABAergic Source: Ensembl
  4. positive regulation of gamma-aminobutyric acid secretion Source: Ensembl
  5. protein homooligomerization Source: Ensembl
  6. response to calcium ion Source: Ensembl
  7. response to cocaine Source: Ensembl
  8. response to estradiol Source: Ensembl
  9. response to lead ion Source: Ensembl
  10. response to purine-containing compound Source: Ensembl
  11. response to sucrose Source: Ensembl
  12. response to toxic substance Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sodium- and chloride-dependent GABA transporter 1Imported
Gene namesi
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:11042. SLC6A1.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: Ensembl
  2. cell surface Source: Ensembl
  3. plasma membrane Source: Ensembl
Complete GO annotation...


Gene expression databases

ExpressionAtlasiC9J5P8. baseline and differential.

Family & Domainsi

Phylogenomic databases



Sequence statusi: Fragment.

C9J5P8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30 
Mass (Da):4,012
Last modified:October 29, 2014 - v3

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei39 – 391Imported

Sequence databases

Select the link destinations:
Links Updated
AC024910 Genomic DNA. No translation available.
KF457578 Genomic DNA. No translation available.
KF457580 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000425938; ENSP00000411689; ENSG00000157103.


Sequence databases

Select the link destinations:
Links Updated
AC024910 Genomic DNA. No translation available.
KF457578 Genomic DNA. No translation available.
KF457580 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000425938 ; ENSP00000411689 ; ENSG00000157103 .

Organism-specific databases

HGNCi HGNC:11042. SLC6A1.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118857.

Miscellaneous databases

ChiTaRSi SLC6A1. human.
NextBioi 35485095.

Gene expression databases

Bgeei C9J5P8.
ExpressionAtlasi C9J5P8. baseline and differential.

Family and domain databases

ProtoNeti Search...


« Hide 'large scale' publications
  1. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9J5P8_HUMAN
AccessioniPrimary (citable) accession number: C9J5P8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 29, 2014
Last modified: January 7, 2015
This is version 35 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.



The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.