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C9J5P8

- C9J5P8_HUMAN

UniProt

C9J5P8 - C9J5P8_HUMAN

Protein
Submitted name:

Sodium- and chloride-dependent GABA transporter 1

Gene

SLC6A1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. gamma-aminobutyric acid:sodium symporter activity Source: Ensembl

    GO - Biological processi

    1. gamma-aminobutyric acid import Source: Ensembl
    2. learning Source: Ensembl
    3. negative regulation of synaptic transmission, GABAergic Source: Ensembl
    4. positive regulation of gamma-aminobutyric acid secretion Source: Ensembl
    5. protein homooligomerization Source: Ensembl
    6. response to calcium ion Source: Ensembl
    7. response to cocaine Source: Ensembl
    8. response to estradiol Source: Ensembl
    9. response to lead ion Source: Ensembl
    10. response to purine-containing compound Source: Ensembl
    11. response to sucrose Source: Ensembl
    12. response to toxic substance Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sodium- and chloride-dependent GABA transporter 1Imported
    Gene namesi
    Name:SLC6A1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:11042. SLC6A1.

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: Ensembl
    2. cell surface Source: Ensembl
    3. plasma membrane Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiC9J5P8.
    BgeeiC9J5P8.

    Sequencei

    Sequence statusi: Fragment.

    C9J5P8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATNGSKVAD GQISTEVSEA PVANDKPKTL VVKVQKKA                38
    Length:38
    Mass (Da):3,941
    Last modified:May 14, 2014 - v2
    Checksum:i233A7D170A9FD690
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei38 – 381Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC024910 Genomic DNA. No translation available.
    KF457578 Genomic DNA. No translation available.
    KF457580 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000425938; ENSP00000411689; ENSG00000157103.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC024910 Genomic DNA. No translation available.
    KF457578 Genomic DNA. No translation available.
    KF457580 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000425938 ; ENSP00000411689 ; ENSG00000157103 .

    Organism-specific databases

    HGNCi HGNC:11042. SLC6A1.
    GenAtlasi Search...

    Miscellaneous databases

    NextBioi 35485095.

    Gene expression databases

    ArrayExpressi C9J5P8.
    Bgeei C9J5P8.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
      , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
      Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9J5P8_HUMAN
    AccessioniPrimary (citable) accession number: C9J5P8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: May 14, 2014
    Last modified: October 1, 2014
    This is version 32 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3