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Protein
Submitted name:

Protein PTGES3L-AARSD1

Gene

PTGES3L-AARSD1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. alanine-tRNA ligase activity Source: InterPro
  2. ATP binding Source: InterPro
  3. nucleic acid binding Source: InterPro

GO - Biological processi

  1. alanyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein PTGES3L-AARSD1Imported
Gene namesi
Name:PTGES3L-AARSD1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:43946. PTGES3L-AARSD1.

PTM / Processingi

Proteomic databases

MaxQBiC9J5N1.

Expressioni

Gene expression databases

BgeeiC9J5N1.
ExpressionAtlasiC9J5N1. baseline.

Structurei

3D structure databases

ProteinModelPortaliC9J5N1.
SMRiC9J5N1. Positions 1-79, 81-489.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00510000046493.
HOGENOMiHOG000230967.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR018165. Ala-tRNA-synth_IIc_core.
IPR018164. Ala-tRNA-synth_IIc_N.
IPR007052. CS_dom.
IPR008978. HSP20-like_chaperone.
IPR018163. Thr/Ala-tRNA-synth_IIc_edit.
IPR009000. Transl_B-barrel.
IPR012947. tRNA_SAD.
[Graphical view]
PfamiPF01411. tRNA-synt_2c. 1 hit.
PF07973. tRNA_SAD. 1 hit.
[Graphical view]
SMARTiSM00863. tRNA_SAD. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
SSF50447. SSF50447. 1 hit.
SSF55186. SSF55186. 1 hit.
PROSITEiPS50860. AA_TRNA_LIGASE_II_ALA. 1 hit.
PS51203. CS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9J5N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFCVEDSTD VHVLIEDHRI VFSCKNADGV ELYNEIEFYA KVNSKDSQDK
60 70 80 90 100
RSSRSITCFV RKWKEKVAWP RLTKEDIKLL KKVSTKRPPP AMDDLDFTTT
110 120 130 140 150
VVSCCPAELQ TEGSNGKKEV LSGFQVVLED TVLFPEGGGQ PDDRGTINDI
160 170 180 190 200
SVLRVTRRGE QADHFTQTPL DPGSQVLVRV DWERRFDHMQ QHSGQHLITA
210 220 230 240 250
VADHLFKLKT TSWELGRFRS AIELDTPSMT AEQVAAIEQS VNEKIRDRLP
260 270 280 290 300
VNVRELSLDD PEVEQVSGRG LPDDHAGPIR VVNIEGVDSN MCCGTHVSNL
310 320 330 340 350
SDLQVIKILG TEKGKKNRTN LIFLSGNRVL KWMERSHGTE KALTALLKCG
360 370 380 390 400
AEDHVEAVKK LQNSTKILQK NNLNLLRDLA VHIAHSLRNS PDWGGVVILH
410 420 430 440 450
RKEGDSEFMN IIANEIGSEE TLLFLTVGDE KGGGLFLLAG PPASVETLGP
460 470 480 490
RVAEVLEGKG AGKKGRFQGK ATKMSRRMEA QALLQDYIST QSAKE
Length:495
Mass (Da):55,066
Last modified:November 3, 2009 - v1
Checksum:iEBB6575CC3625575
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC055866 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000409103; ENSP00000386254; ENSG00000108825.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC055866 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliC9J5N1.
SMRiC9J5N1. Positions 1-79, 81-489.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiC9J5N1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000409103; ENSP00000386254; ENSG00000108825.

Organism-specific databases

HGNCiHGNC:43946. PTGES3L-AARSD1.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00510000046493.
HOGENOMiHOG000230967.

Miscellaneous databases

NextBioi35485088.

Gene expression databases

BgeeiC9J5N1.
ExpressionAtlasiC9J5N1. baseline.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR018165. Ala-tRNA-synth_IIc_core.
IPR018164. Ala-tRNA-synth_IIc_N.
IPR007052. CS_dom.
IPR008978. HSP20-like_chaperone.
IPR018163. Thr/Ala-tRNA-synth_IIc_edit.
IPR009000. Transl_B-barrel.
IPR012947. tRNA_SAD.
[Graphical view]
PfamiPF01411. tRNA-synt_2c. 1 hit.
PF07973. tRNA_SAD. 1 hit.
[Graphical view]
SMARTiSM00863. tRNA_SAD. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
SSF50447. SSF50447. 1 hit.
SSF55186. SSF55186. 1 hit.
PROSITEiPS50860. AA_TRNA_LIGASE_II_ALA. 1 hit.
PS51203. CS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9J5N1_HUMAN
AccessioniPrimary (citable) accession number: C9J5N1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: April 29, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.