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C9J4Q0

- C9J4Q0_HUMAN

UniProt

C9J4Q0 - C9J4Q0_HUMAN

Protein
Submitted name:

CASP8 and FADD-like apoptosis regulator

Gene

CFLAR

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. negative regulation of apoptotic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CASP8 and FADD-like apoptosis regulatorImported
    Gene namesi
    Name:CFLARImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:1876. CFLAR.

    Subcellular locationi

    GO - Cellular componenti

    1. CD95 death-inducing signaling complex Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiC9J4Q0.
    BgeeiC9J4Q0.

    Structurei

    3D structure databases

    ProteinModelPortaliC9J4Q0.
    SMRiC9J4Q0. Positions 1-64.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR011029. DEATH-like_dom.
    IPR001875. DED.
    [Graphical view]
    PfamiPF01335. DED. 1 hit.
    [Graphical view]
    SUPFAMiSSF47986. SSF47986. 1 hit.
    PROSITEiPS50168. DED. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    C9J4Q0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL   50
    SVGDLAELLY RVRR 64
    Length:64
    Mass (Da):7,378
    Last modified:November 3, 2009 - v1
    Checksum:iEAC7F74BB8D4C38F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei64 – 641Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007283 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000433445; ENSP00000391029; ENSG00000003402.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007283 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali C9J4Q0.
    SMRi C9J4Q0. Positions 1-64.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000433445 ; ENSP00000391029 ; ENSG00000003402 .

    Organism-specific databases

    HGNCi HGNC:1876. CFLAR.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi CFLAR. human.
    NextBioi 35484971.

    Gene expression databases

    ArrayExpressi C9J4Q0.
    Bgeei C9J4Q0.

    Family and domain databases

    InterProi IPR011029. DEATH-like_dom.
    IPR001875. DED.
    [Graphical view ]
    Pfami PF01335. DED. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47986. SSF47986. 1 hit.
    PROSITEi PS50168. DED. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9J4Q0_HUMAN
    AccessioniPrimary (citable) accession number: C9J4Q0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3