C9J4G7 (C9J4G7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-oxoglutarate dehydrogenase, mitochondrial Ensembl ENSP00000411830

Gene names

Name:

OGDH Ensembl ENSP00000411830

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000411830

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	211 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000411830

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	2-oxoglutarate metabolic process Inferred from electronic annotation. Source: Compara NADH metabolic process Inferred from electronic annotation. Source: Compara cerebellar cortex development Inferred from electronic annotation. Source: Compara hippocampus development Inferred from electronic annotation. Source: Compara olfactory bulb mitral cell layer development Inferred from electronic annotation. Source: Compara pyramidal neuron development Inferred from electronic annotation. Source: Compara striatum development Inferred from electronic annotation. Source: Compara succinyl-CoA metabolic process Inferred from electronic annotation. Source: Compara tangential migration from the subventricular zone to the olfactory bulb Inferred from electronic annotation. Source: Compara thalamus development Inferred from electronic annotation. Source: Compara tricarboxylic acid cycle Inferred from electronic annotation. Source: Compara
Cellular_component	mitochondrion Inferred from direct assay. Source: HPA oxoglutarate dehydrogenase complex Inferred from electronic annotation. Source: Compara
Molecular_function	oxoglutarate dehydrogenase (NAD+) activity Inferred from electronic annotation. Source: Compara oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: InterPro thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	211	1	Ensembl ENSP00000411830

Sequences

	Sequence		Length	Mass (Da)
	C9J4G7 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 42B1862ECB492A84	FASTA	211	23,191
	10 20 30 40 50 60 MFHLRTCAAK LRPLTASQTV KTFSQNRPAA ARTFQQIRCY SAPVAAEPFL SGTSSNYVEE 70 80 90 100 110 120 MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLPLS RGSLAAVAHA QSLVEAQPNV 130 140 150 160 170 180 DKLVEDHLAV QSLIRAYQIR GHHVAQLDPL GILDADLDSS VPADIISSTD KLGFYGLDES 190 200 210 DLDKVFHLPT TTFIGGQESA LPLREIIRRL E

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC004859 Genomic DNA. No translation available. AC011894 Genomic DNA. No translation available.
IPI	IPI00927344.
3D structure databases
ProteinModelPortal	C9J4G7.
SMR	C9J4G7. Positions 54-211.
ModBase	Search...
Protein-protein interaction databases
STRING	C9J4G7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000419661; ENSP00000411830; ENSG00000105953.
Organism-specific databases
HGNC	HGNC:8124. OGDH.
GenAtlas	Search...
Gene expression databases
ArrayExpress	C9J4G7.
Bgee	C9J4G7.
Family and domain databases
InterPro	IPR011603. 2oxoglutarate_DH_E1. [Graphical view]
PANTHER	PTHR23152. PTHR23152. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	OGDH. human.
NextBio	35484934.

Entry information

Entry name

C9J4G7_HUMAN

Accession

Primary (citable) accession number: C9J4G7

Entry history

Integrated into UniProtKB/TrEMBL:	November 3, 2009
Last sequence update:	November 3, 2009
Last modified:	April 3, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.