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C9J4G7

- C9J4G7_HUMAN

UniProt

C9J4G7 - C9J4G7_HUMAN

Protein
Submitted name:

2-oxoglutarate dehydrogenase, mitochondrial

Gene

OGDH

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. oxoglutarate dehydrogenase (NAD+) activity Source: Ensembl
    2. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
    3. thiamine pyrophosphate binding Source: InterPro

    GO - Biological processi

    1. 2-oxoglutarate metabolic process Source: Ensembl
    2. cerebellar cortex development Source: Ensembl
    3. hippocampus development Source: Ensembl
    4. NADH metabolic process Source: Ensembl
    5. olfactory bulb mitral cell layer development Source: Ensembl
    6. pyramidal neuron development Source: Ensembl
    7. striatum development Source: Ensembl
    8. succinyl-CoA metabolic process Source: Ensembl
    9. tangential migration from the subventricular zone to the olfactory bulb Source: Ensembl
    10. thalamus development Source: Ensembl
    11. tricarboxylic acid cycle Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    2-oxoglutarate dehydrogenase, mitochondrialImported
    Gene namesi
    Name:OGDHImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:8124. OGDH.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrion Source: HPA
    2. oxoglutarate dehydrogenase complex Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiC9J4G7.
    BgeeiC9J4G7.

    Structurei

    3D structure databases

    ProteinModelPortaliC9J4G7.
    SMRiC9J4G7. Positions 54-211.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR011603. 2oxoglutarate_DH_E1.
    [Graphical view]
    PANTHERiPTHR23152. PTHR23152. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    C9J4G7-1 [UniParc]FASTAAdd to Basket

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    MFHLRTCAAK LRPLTASQTV KTFSQNRPAA ARTFQQIRCY SAPVAAEPFL    50
    SGTSSNYVEE MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLPLS 100
    RGSLAAVAHA QSLVEAQPNV DKLVEDHLAV QSLIRAYQIR GHHVAQLDPL 150
    GILDADLDSS VPADIISSTD KLGFYGLDES DLDKVFHLPT TTFIGGQESA 200
    LPLREIIRRL E 211
    Length:211
    Mass (Da):23,191
    Last modified:November 3, 2009 - v1
    Checksum:i42B1862ECB492A84
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei211 – 2111Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004859 Genomic DNA. No translation available.
    AC011894 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000419661; ENSP00000411830; ENSG00000105953.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004859 Genomic DNA. No translation available.
    AC011894 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali C9J4G7.
    SMRi C9J4G7. Positions 54-211.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000419661 ; ENSP00000411830 ; ENSG00000105953 .

    Organism-specific databases

    HGNCi HGNC:8124. OGDH.
    GenAtlasi Search...

    Miscellaneous databases

    ChiTaRSi OGDH. human.
    NextBioi 35484934.

    Gene expression databases

    ArrayExpressi C9J4G7.
    Bgeei C9J4G7.

    Family and domain databases

    InterProi IPR011603. 2oxoglutarate_DH_E1.
    [Graphical view ]
    PANTHERi PTHR23152. PTHR23152. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of human chromosome 7."
      Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
      , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
      Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9J4G7_HUMAN
    AccessioniPrimary (citable) accession number: C9J4G7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3