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C9J4G7

- C9J4G7_HUMAN

UniProt

C9J4G7 - C9J4G7_HUMAN

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Protein
Submitted name:

2-oxoglutarate dehydrogenase, mitochondrial

Gene

OGDH

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (NAD+) activity Source: Ensembl
  2. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
  3. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. 2-oxoglutarate metabolic process Source: Ensembl
  2. cerebellar cortex development Source: Ensembl
  3. hippocampus development Source: Ensembl
  4. NADH metabolic process Source: Ensembl
  5. olfactory bulb mitral cell layer development Source: Ensembl
  6. pyramidal neuron development Source: Ensembl
  7. striatum development Source: Ensembl
  8. succinyl-CoA metabolic process Source: Ensembl
  9. tangential migration from the subventricular zone to the olfactory bulb Source: Ensembl
  10. thalamus development Source: Ensembl
  11. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, mitochondrialImported
Gene namesi
Name:OGDHImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:8124. OGDH.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: HPA
  2. oxoglutarate dehydrogenase complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiC9J4G7.
ExpressionAtlasiC9J4G7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9J4G7.
SMRiC9J4G7. Positions 54-211.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063092.

Family and domain databases

InterProiIPR011603. 2oxoglutarate_DH_E1.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9J4G7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFHLRTCAAK LRPLTASQTV KTFSQNRPAA ARTFQQIRCY SAPVAAEPFL
60 70 80 90 100
SGTSSNYVEE MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLPLS
110 120 130 140 150
RGSLAAVAHA QSLVEAQPNV DKLVEDHLAV QSLIRAYQIR GHHVAQLDPL
160 170 180 190 200
GILDADLDSS VPADIISSTD KLGFYGLDES DLDKVFHLPT TTFIGGQESA
210
LPLREIIRRL E
Length:211
Mass (Da):23,191
Last modified:November 3, 2009 - v1
Checksum:i42B1862ECB492A84
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei211 – 2111Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004859 Genomic DNA. No translation available.
AC011894 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000419661; ENSP00000411830; ENSG00000105953.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004859 Genomic DNA. No translation available.
AC011894 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali C9J4G7.
SMRi C9J4G7. Positions 54-211.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000419661 ; ENSP00000411830 ; ENSG00000105953 .

Organism-specific databases

HGNCi HGNC:8124. OGDH.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00530000063092.

Miscellaneous databases

ChiTaRSi OGDH. human.
NextBioi 35484934.

Gene expression databases

Bgeei C9J4G7.
ExpressionAtlasi C9J4G7. baseline and differential.

Family and domain databases

InterProi IPR011603. 2oxoglutarate_DH_E1.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9J4G7_HUMAN
AccessioniPrimary (citable) accession number: C9J4G7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: November 26, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3