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Protein

Uncharacterized protein C22orf46

Gene

C22orf46

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-32414-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C22orf46
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

HGNCiHGNC:26294. C22orf46.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000184208.
PharmGKBiPA165378333.

Polymorphism and mutation databases

BioMutaiC22orf46.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000039421818 – 243Uncharacterized protein C22orf46Add BLAST226

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi30N-linked (GlcNAc...)Sequence analysis1
Glycosylationi165N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiC9J442.
PRIDEiC9J442.

PTM databases

iPTMnetiC9J442.
PhosphoSitePlusiC9J442.

Expressioni

Gene expression databases

BgeeiENSG00000184208.
GenevisibleiC9J442. HS.

Organism-specific databases

HPAiHPA052741.
HPA057048.

Interactioni

Protein-protein interaction databases

BioGridi122768. 3 interactors.

Structurei

3D structure databases

ProteinModelPortaliC9J442.
SMRiC9J442.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IIN7. Eukaryota.
ENOG4111836. LUCA.
GeneTreeiENSGT00580000082148.
HOGENOMiHOG000206575.
InParanoidiC9J442.
OMAiPSMRCET.
OrthoDBiEOG091G012C.
PhylomeDBiC9J442.

Family and domain databases

InterProiIPR031715. DUF4727.
[Graphical view]
PfamiPF15856. DUF4727. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C9J442-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLSLLGACA VVGPFHGPEW EPVQGLLSQN HSCRDPQCCG NLLVLCLFLV
60 70 80 90 100
WQVRHCWHQV TRTRFSTRNV IKVPLQKRAV PSMRCETVFK LTPEFFSPGK
110 120 130 140 150
SRGLDSQQCA QRQRWGYRRS LQESWAQNLL SPQHPCPGPP SGVHTHSEPI
160 170 180 190 200
FCTTSISNTC LLPQNSSWKA WQVPWCLHDG QTRPALDMCQ EMEQLLLHSQ
210 220 230 240
ERLVSLEPVI SVRSRPTSMT LTTSLPNLLS AERLQFCPQR APA
Length:243
Mass (Da):27,532
Last modified:November 3, 2009 - v1
Checksum:i08DAD81D145A1F89
GO

Sequence cautioni

The sequence EAW60455 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83840 Genomic DNA. No translation available.
CH471095 Genomic DNA. Translation: EAW60455.1. Sequence problems.
BC035403 mRNA. No translation available.
CCDSiCCDS46717.1.
RefSeqiNP_001136436.1. NM_001142964.1.
UniGeneiHs.517653.

Genome annotation databases

EnsembliENST00000402966; ENSP00000385467; ENSG00000184208.
GeneIDi79640.
KEGGihsa:79640.
UCSCiuc003bax.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83840 Genomic DNA. No translation available.
CH471095 Genomic DNA. Translation: EAW60455.1. Sequence problems.
BC035403 mRNA. No translation available.
CCDSiCCDS46717.1.
RefSeqiNP_001136436.1. NM_001142964.1.
UniGeneiHs.517653.

3D structure databases

ProteinModelPortaliC9J442.
SMRiC9J442.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122768. 3 interactors.

PTM databases

iPTMnetiC9J442.
PhosphoSitePlusiC9J442.

Polymorphism and mutation databases

BioMutaiC22orf46.

Proteomic databases

PaxDbiC9J442.
PRIDEiC9J442.

Protocols and materials databases

DNASUi79640.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000402966; ENSP00000385467; ENSG00000184208.
GeneIDi79640.
KEGGihsa:79640.
UCSCiuc003bax.1. human.

Organism-specific databases

CTDi79640.
GeneCardsiC22orf46.
HGNCiHGNC:26294. C22orf46.
HPAiHPA052741.
HPA057048.
neXtProtiNX_C9J442.
OpenTargetsiENSG00000184208.
PharmGKBiPA165378333.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IIN7. Eukaryota.
ENOG4111836. LUCA.
GeneTreeiENSGT00580000082148.
HOGENOMiHOG000206575.
InParanoidiC9J442.
OMAiPSMRCET.
OrthoDBiEOG091G012C.
PhylomeDBiC9J442.

Enzyme and pathway databases

BioCyciZFISH:G66-32414-MONOMER.

Miscellaneous databases

ChiTaRSiC22orf46. human.
GenomeRNAii79640.
PROiC9J442.

Gene expression databases

BgeeiENSG00000184208.
GenevisibleiC9J442. HS.

Family and domain databases

InterProiIPR031715. DUF4727.
[Graphical view]
PfamiPF15856. DUF4727. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCV046_HUMAN
AccessioniPrimary (citable) accession number: C9J442
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: November 3, 2009
Last modified: November 2, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.