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Protein
Submitted name:

CASP8 and FADD-like apoptosis regulator

Gene

CFLAR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CASP8 and FADD-like apoptosis regulatorImported
Gene namesi
Name:CFLARImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000003402.19.
HGNCiHGNC:1876. CFLAR.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000003402.

PTM / Processingi

Proteomic databases

MaxQBiC9J408.
PaxDbiC9J408.
PeptideAtlasiC9J408.
PRIDEiC9J408.

Expressioni

Gene expression databases

BgeeiENSG00000003402.
ExpressionAtlasiC9J408. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9J408.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 73DEDInterPro annotationAdd BLAST73
Domaini92 – 129DEDInterPro annotationAdd BLAST38

Phylogenomic databases

eggNOGiKOG3573. Eukaryota.
ENOG410ZQIE. LUCA.
GeneTreeiENSGT00530000064199.
HOGENOMiHOG000069972.

Family and domain databases

InterProiView protein in InterPro
IPR011029. DEATH-like_dom_sf.
IPR001875. DED_dom.
PfamiView protein in Pfam
PF01335. DED. 1 hit.
SMARTiView protein in SMART
SM00031. DED. 1 hit.
SUPFAMiSSF47986. SSF47986. 2 hits.
PROSITEiView protein in PROSITE
PS50168. DED. 2 hits.

Sequencei

Sequence statusi: Fragment.

C9J408-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL
60 70 80 90 100
SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI
110 120
GEDLDKSDVS SLIFLMKDYM GRGKISKEK
Length:129
Mass (Da):14,968
Last modified:November 3, 2009 - v1
Checksum:i5D1B1A19FAB862BE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei129Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007283 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000441224; ENSP00000411897; ENSG00000003402.
UCSCiuc061rhz.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9J408_HUMAN
AccessioniPrimary (citable) accession number: C9J408
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: November 22, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported