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C9J408

- C9J408_HUMAN

UniProt

C9J408 - C9J408_HUMAN

Protein
Submitted name:

CASP8 and FADD-like apoptosis regulator

Gene

CFLAR

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. negative regulation of apoptotic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CASP8 and FADD-like apoptosis regulatorImported
    Gene namesi
    Name:CFLARImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:1876. CFLAR.

    Subcellular locationi

    GO - Cellular componenti

    1. CD95 death-inducing signaling complex Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiC9J408.
    BgeeiC9J408.

    Structurei

    3D structure databases

    ProteinModelPortaliC9J408.
    SMRiC9J408. Positions 3-125.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000069972.

    Family and domain databases

    Gene3Di1.10.533.10. 2 hits.
    InterProiIPR011029. DEATH-like_dom.
    IPR001875. DED.
    [Graphical view]
    PfamiPF01335. DED. 2 hits.
    [Graphical view]
    SMARTiSM00031. DED. 1 hit.
    [Graphical view]
    SUPFAMiSSF47986. SSF47986. 2 hits.
    PROSITEiPS50168. DED. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    C9J408-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL    50
    SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI 100
    GEDLDKSDVS SLIFLMKDYM GRGKISKEK 129
    Length:129
    Mass (Da):14,968
    Last modified:November 3, 2009 - v1
    Checksum:i5D1B1A19FAB862BE
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei129 – 1291Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007283 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000441224; ENSP00000411897; ENSG00000003402.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007283 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali C9J408.
    SMRi C9J408. Positions 3-125.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000441224 ; ENSP00000411897 ; ENSG00000003402 .

    Organism-specific databases

    HGNCi HGNC:1876. CFLAR.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000069972.

    Miscellaneous databases

    ChiTaRSi CFLAR. human.
    NextBioi 35484884.

    Gene expression databases

    ArrayExpressi C9J408.
    Bgeei C9J408.

    Family and domain databases

    Gene3Di 1.10.533.10. 2 hits.
    InterProi IPR011029. DEATH-like_dom.
    IPR001875. DED.
    [Graphical view ]
    Pfami PF01335. DED. 2 hits.
    [Graphical view ]
    SMARTi SM00031. DED. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47986. SSF47986. 2 hits.
    PROSITEi PS50168. DED. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9J408_HUMAN
    AccessioniPrimary (citable) accession number: C9J408
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3