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Protein
Submitted name:

Cyclin E variant ex7del

Gene

CCNE1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionCyclinUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin E variant ex7delImported
Submitted name:
G1/S-specific cyclin-E1Imported
Gene namesi
Name:CCNE1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000105173.13
HGNCiHGNC:1589 CCNE1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000105173

PTM / Processingi

Proteomic databases

PeptideAtlasiC9J2U0

Expressioni

Gene expression databases

BgeeiENSG00000105173

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini130 – 161Cyclin N-terminalInterPro annotationAdd BLAST32

Sequence similaritiesi

Belongs to the cyclin family.UniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118939
HOGENOMiHOG000231743

Family and domain databases

CDDicd00043 CYCLIN, 1 hit
InterProiView protein in InterPro
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR004367 Cyclin_C-dom
IPR028858 Cyclin_E
IPR006671 Cyclin_N
PANTHERiPTHR10177:SF71 PTHR10177:SF71, 2 hits
PfamiView protein in Pfam
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 1 hit
SM01332 Cyclin_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits
PROSITEiView protein in PROSITE
PS00292 CYCLINS, 1 hit

Sequencei

Sequence statusi: Complete.

C9J2U0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEDGGAEFS ARSRKRKANV TVFLQDPDEE MAKIDRTARD QCGSQPWDNN
60 70 80 90 100
AVCADPCSLI PTPDKEDDDR VYPNSTCKPR IIAPSRGSPL PVLSWANREE
110 120 130 140 150
VWKIMLNKEK TYLRDQHFLE QHPLLQPKMR AILLDWLMEV CEVYKLHRET
160 170 180 190 200
FYLAQDFFDR YMATQENVVK TLLQLIGISS LFIAAKLEEI YPPKLHQFAY
210 220 230 240 250
VTDGACSGDE ILTMELMIMK LLDLCVLDVD CLEFPYGILA ASALYHFSSS
260 270 280 290 300
ELMQKVSGYQ WCDIENCVKW MVPFAMVIRE TGSSKLKHFR GVADEDAHNI
310 320 330 340 350
QTHRDSLDLL DKARAKKAML SEQNRASPLP SGLLTPPQSG KKQSSGPEMA
Length:350
Mass (Da):39,812
Last modified:October 29, 2014 - v3
Checksum:iDA4FAE0D8859781F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008798 Genomic DNA No translation available.
KF672847 mRNA Translation: AHC02488.1
UniGeneiHs.244723

Genome annotation databases

EnsembliENST00000357943; ENSP00000350625; ENSG00000105173
UCSCiuc032hte.1 human

Similar proteinsi

Entry informationi

Entry nameiC9J2U0_HUMAN
AccessioniPrimary (citable) accession number: C9J2U0
Secondary accession number(s): V5W643
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 29, 2014
Last modified: April 25, 2018
This is version 74 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health