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C9J1R3

- C9J1R3_HUMAN

UniProt

C9J1R3 - C9J1R3_HUMAN

Protein
Submitted name:

Activin receptor type-1

Gene

ACVR1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. activin receptor activity, type I Source: Ensembl
    2. ATP binding Source: InterPro
    3. receptor signaling protein serine/threonine kinase activity Source: Ensembl
    4. transforming growth factor beta receptor activity, type I Source: Ensembl

    GO - Biological processi

    1. acute inflammatory response Source: Ensembl
    2. cellular response to glucocorticoid stimulus Source: Ensembl
    3. determination of left/right symmetry Source: Ensembl
    4. gastrulation with mouth forming second Source: Ensembl
    5. germ cell development Source: Ensembl
    6. heart development Source: Ensembl
    7. in utero embryonic development Source: Ensembl
    8. mesoderm formation Source: Ensembl
    9. neural crest cell migration Source: Ensembl
    10. patterning of blood vessels Source: Ensembl
    11. pharyngeal system development Source: Ensembl
    12. regulation of skeletal muscle tissue development Source: Ensembl
    13. smooth muscle cell differentiation Source: Ensembl
    14. transforming growth factor beta receptor signaling pathway Source: Ensembl
    15. urogenital system development Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Activin receptor type-1Imported
    Gene namesi
    Name:ACVR1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:171. ACVR1.

    Subcellular locationi

    GO - Cellular componenti

    1. activin receptor complex Source: Ensembl
    2. apical part of cell Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiC9J1R3.
    BgeeiC9J1R3.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliC9J1R3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    InterProiIPR000333. TGFB_receptor.
    [Graphical view]
    PANTHERiPTHR23255. PTHR23255. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    C9J1R3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVDGVMILPV LIMIALPSPS MEDEKPKVNP KLYMCVCEGL SCGNEDHCEG   50
    QQCFSSLSIN DGFHVYQKGC F 71
    Length:71
    Mass (Da):7,828
    Last modified:November 3, 2009 - v1
    Checksum:iE5B3BADEFB8CAB49
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei71 – 711Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC013731 Genomic DNA. No translation available.
    AC019186 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000424669; ENSP00000400767; ENSG00000115170.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC013731 Genomic DNA. No translation available.
    AC019186 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali C9J1R3.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi C9J1R3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000424669 ; ENSP00000400767 ; ENSG00000115170 .

    Organism-specific databases

    HGNCi HGNC:171. ACVR1.
    GenAtlasi Search...

    Miscellaneous databases

    NextBioi 35484611.

    Gene expression databases

    ArrayExpressi C9J1R3.
    Bgeei C9J1R3.

    Family and domain databases

    InterProi IPR000333. TGFB_receptor.
    [Graphical view ]
    PANTHERi PTHR23255. PTHR23255. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9J1R3_HUMAN
    AccessioniPrimary (citable) accession number: C9J1R3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3