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Protein
Submitted name:

Adenylate cyclase 1 (Brain), isoform CRA_e

Gene

ADCY1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
LigandNucleotide-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclase 1 (Brain), isoform CRA_eImported
Submitted name:
Adenylate cyclase type 1Imported
Gene namesi
Name:ADCY1Imported
ORF Names:hCG_19245Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000164742.14
HGNCiHGNC:232 ADCY1

Subcellular locationi

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000164742

PTM / Processingi

Proteomic databases

PeptideAtlasiC9J1J0

Expressioni

Gene expression databases

BgeeiENSG00000164742

Structurei

3D structure databases

SMRiC9J1J0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 205Guanylate cyclaseInterPro annotationAdd BLAST128

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG3619 Eukaryota
COG2114 LUCA
GeneTreeiENSGT00760000119042
HOGENOMiHOG000171578

Family and domain databases

Gene3Di3.30.70.12301 hit
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR018297 A/G_cyclase_CS
IPR032628 AC_N
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF16214 AC_N, 1 hit
PF00211 Guanylate_cyc, 1 hit
SMARTiView protein in SMART
SM00044 CYCc, 1 hit
SUPFAMiSSF55073 SSF55073, 1 hit
PROSITEiView protein in PROSITE
PS00452 GUANYLATE_CYCLASE_1, 1 hit
PS50125 GUANYLATE_CYCLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

C9J1J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYGVFVRILT ERSQRKAFLQ ARSCIEDRLR LEDENEKQER LLMSLLPRNV
60 70 80 90 100
AMEMKEDFLK PPERIFHKIY IQRHDNVSIL FADIVGFTGL ASQCTAQELV
110 120 130 140 150
KLLNELFGKF DELATENHCR RIKILGDCYY CVSGLTQPKT DHAHCCVEMG
160 170 180 190 200
LDMIDTITSV AEATEVDLNM RVGLHTGRVL CGVLGLRKWQ YDVWSNDVTL
210 220 230 240 250
ANVMEAAGLP GKVHITKTTL ACLNGDYEVE PGYGHERNSF LKTHNIETFF
260 270 280 290 300
IVPSHRRKIF PGLILSDIKP AKRMKFKTVC YLLVQLMHCR KMFKAEIPFS
310 320 330
NVMTCEDDDK VQIHPSLSGL DVLLGFWSPT LQRGRLCT
Length:338
Mass (Da):38,688
Last modified:November 3, 2009 - v1
Checksum:iF268F27185D9AECB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069008 Genomic DNA No translation available.
AC091439 Genomic DNA No translation available.
CH471128 Genomic DNA Translation: EAW61047.1
RefSeqiNP_001268697.1, NM_001281768.1
UniGeneiHs.192215

Genome annotation databases

EnsembliENST00000432715; ENSP00000392721; ENSG00000164742
ENST00000621543; ENSP00000479770; ENSG00000164742
GeneIDi107
UCSCiuc003tnd.3 human

Similar proteinsi

Entry informationi

Entry nameiC9J1J0_HUMAN
AccessioniPrimary (citable) accession number: C9J1J0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: April 25, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported