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Protein
Submitted name:

Adenylate cyclase 1 (Brain), isoform CRA_e

Gene

ADCY1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
LigandNucleotide-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclase 1 (Brain), isoform CRA_eImported
Submitted name:
Adenylate cyclase type 1Imported
Gene namesi
Name:ADCY1Imported
ORF Names:hCG_19245Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000164742.14.
HGNCiHGNC:232. ADCY1.

Subcellular locationi

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000164742.

Expressioni

Gene expression databases

BgeeiENSG00000164742.
ExpressionAtlasiC9J1J0. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 205Guanylate cyclaseInterPro annotationAdd BLAST128

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG3619. Eukaryota.
COG2114. LUCA.
GeneTreeiENSGT00760000119042.
HOGENOMiHOG000171578.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiView protein in InterPro
IPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR032628. AC_N.
IPR029787. Nucleotide_cyclase.
PfamiView protein in Pfam
PF16214. AC_N. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
SMARTiView protein in SMART
SM00044. CYCc. 1 hit.
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiView protein in PROSITE
PS00452. GUANYLATE_CYCLASE_1. 1 hit.
PS50125. GUANYLATE_CYCLASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C9J1J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYGVFVRILT ERSQRKAFLQ ARSCIEDRLR LEDENEKQER LLMSLLPRNV
60 70 80 90 100
AMEMKEDFLK PPERIFHKIY IQRHDNVSIL FADIVGFTGL ASQCTAQELV
110 120 130 140 150
KLLNELFGKF DELATENHCR RIKILGDCYY CVSGLTQPKT DHAHCCVEMG
160 170 180 190 200
LDMIDTITSV AEATEVDLNM RVGLHTGRVL CGVLGLRKWQ YDVWSNDVTL
210 220 230 240 250
ANVMEAAGLP GKVHITKTTL ACLNGDYEVE PGYGHERNSF LKTHNIETFF
260 270 280 290 300
IVPSHRRKIF PGLILSDIKP AKRMKFKTVC YLLVQLMHCR KMFKAEIPFS
310 320 330
NVMTCEDDDK VQIHPSLSGL DVLLGFWSPT LQRGRLCT
Length:338
Mass (Da):38,688
Last modified:November 3, 2009 - v1
Checksum:iF268F27185D9AECB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069008 Genomic DNA. No translation available.
AC091439 Genomic DNA. No translation available.
CH471128 Genomic DNA. Translation: EAW61047.1.
RefSeqiNP_001268697.1. NM_001281768.1.
UniGeneiHs.192215.

Genome annotation databases

EnsembliENST00000432715; ENSP00000392721; ENSG00000164742.
ENST00000621543; ENSP00000479770; ENSG00000164742.
GeneIDi107.
UCSCiuc003tnd.3. human.

Similar proteinsi

Entry informationi

Entry nameiC9J1J0_HUMAN
AccessioniPrimary (citable) accession number: C9J1J0
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 27, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported