Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Plasma kallikrein

Gene

KLKB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Plasma kallikreinImported
Gene namesi
Name:KLKB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000164344.15.
HGNCiHGNC:6371. KLKB1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000164344.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500299707720 – 148Sequence analysisAdd BLAST129

Proteomic databases

PaxDbiC9J075.
PeptideAtlasiC9J075.
PRIDEiC9J075.

Expressioni

Gene expression databases

BgeeiENSG00000164344.
ExpressionAtlasiC9J075. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9J075.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 104AppleInterPro annotationAdd BLAST84
Domaini111 – 148AppleInterPro annotationAdd BLAST38

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118962.
HOGENOMiHOG000213704.

Family and domain databases

InterProiView protein in InterPro
IPR000177. Apple.
IPR003609. Pan_app.
IPR034813. Plasma_kallikrein.
PANTHERiPTHR24256:SF313. PTHR24256:SF313. 1 hit.
PfamiView protein in Pfam
PF00024. PAN_1. 2 hits.
PRINTSiPR00005. APPLEDOMAIN.
SMARTiView protein in SMART
SM00223. APPLE. 1 hit.
PROSITEiView protein in PROSITE
PS50948. PAN. 2 hits.

Sequencei

Sequence statusi: Fragment.

C9J075-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILFKQATYF ISLFATVSCG CLTQLYENAF FRGGDVASMY TPNAQYCQMR
60 70 80 90 100
CTFHPRCLLF SFLPASSIND MEKRFGCFLK DSVTGTLPKV HRTGAVSGHS
110 120 130 140
LKQCGHQISA CHRDIYKGVD MRGVNFNVSK VSSVEECQKR CTSNIRCQ
Length:148
Mass (Da):16,620
Last modified:November 3, 2009 - v1
Checksum:iE9CE80E97F2DB638
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei148Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110771 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000428196; ENSP00000412366; ENSG00000164344.
UCSCiuc063bog.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9J075_HUMAN
AccessioniPrimary (citable) accession number: C9J075
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: September 27, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported