C9J069 (CI172_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C9orf172

Gene names

Name:

C9orf172

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	976 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 976	976	Uncharacterized protein C9orf172		PRO_0000392544
Regions
	Compositional bias	68 – 422	355	Pro-rich
Amino acid modifications
	Modified residue	109	1	Phosphoserine By similarity
	Modified residue	129	1	Phosphoserine By similarity
	Modified residue	448	1	Phosphoserine By similarity
	Modified residue	498	1	Phosphothreonine By similarity
	Modified residue	511	1	Phosphothreonine By similarity

Sequences

	Sequence		Length	Mass (Da)
	C9J069 [UniParc]. Last modified November 3, 2009. Version 1. Checksum: 7DB1CCE956BCA47D	FASTA	976	106,650
	10 20 30 40 50 60 MTRTDPPDLL VSTVYQDIKV ATPGPASKCS PCERSVARPA EPAPFNKRHC RSFDFLEALD 70 80 90 100 110 120 GPAMETLPEP PPPESAVPRA RTREAEPRRR ARSKSAPRAP PGLTPAPASP PVLPRRGREA 130 140 150 160 170 180 QRAARAEASP RREPAYPALR ALANELHPIK LQPQRGGPGR VAPLCAAAGR CAPPEPPAGP 190 200 210 220 230 240 APHVRCRLDI KPDDAVLQHA TRGSRSCGPT EAAHWARPAP QFHGLTVPGP RHMALSRTPT 250 260 270 280 290 300 PSDSYCADPR AFYCDGPLPG PRDYAERRSL PFTTPPGPTQ FFYTEEPQGF RGSFAASPGP 310 320 330 340 350 360 TFDAYYPRPY PSEELSGPSP RRMGGYYAGE VRTFPIQEPP SRSYYGEAPR AYGLPYGPRY 370 380 390 400 410 420 VPEEPRAHST ARPFYTEDFG RYRERDVLAR TYPHPRSSPA WADWGPRPYR TLQVVPPSDP 430 440 450 460 470 480 DPLLASWHGG TGTSPPRLAT DSRHYSRSWD NILAPGPRRE DPLGRGRSYE NLLGREVREP 490 500 510 520 530 540 RGVSPEGRRP PVVVNLSTSP RRYAALSLSE TSLTEKGRAG EGLGRNWYVT PEITITDNDL 550 560 570 580 590 600 RATERPSARA WELPGGRTRP PPHAAPDGPT SGRQRSLEQL DELITDLVID SRPTAGQASE 610 620 630 640 650 660 PAADCLGPQL RRLLDSRPAG SGAPALAPPR SPPASAGSAE EPAAPGEAAD ASPEPSADED 670 680 690 700 710 720 DLMTCSNARC RRTETMFNAC LYFKSCHSCY TYYCSRLCRR EDWDAHKARC VYGRVGSVCR 730 740 750 760 770 780 HVLQFCRDSG PVHRAFSRIA RVGFLSRGRG VLFLGFPSPG SADNFLRFGL EGLLLSPTYL 790 800 810 820 830 840 SLRELATHAA PLGSYARELA AAGRLYEPAE CFLLSVSVAV GPGTAPPGTP ALPAPAPRSH 850 860 870 880 890 900 GPTVRKFAKV ALAAGSPARP PPARSREPDM ETLILTPPPG TAGLDQDGEA GRRAREVAFI 910 920 930 940 950 960 HIQRELRLRG VFLRHEFPRV YEQLCEFVEA NRRFTPTTIY PTDRRTGRPF MCMIMAASEP 970 RALDWVASAN LLDDIM

References

[1]

"DNA sequence and analysis of human chromosome 9." Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I. Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL355987 Genomic DNA. No translation available.
IPI	IPI00847762.
RefSeq	NP_001073951.2. NM_001080482.2.
UniGene	Hs.495485.
3D structure databases
ProteinModelPortal	C9J069.
SMR	C9J069. Positions 683-712.
ModBase	Search...
PTM databases
PhosphoSite	C9J069.
Proteomic databases
PaxDb	C9J069.
PRIDE	C9J069.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000436881; ENSP00000412388; ENSG00000232434.
GeneID	389813.
KEGG	hsa:389813.
UCSC	uc011meh.2. human.
Organism-specific databases
CTD	389813.
GeneCards	GC09P139738.
HGNC	HGNC:37284. C9orf172.
HPA	HPA021200.
neXtProt	NX_C9J069.
PharmGKB	PA165585544.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG324574.
HOGENOM	HOG000231560.
OMA	EQLCEFV.
OrthoDB	EOG40S0DZ.
Gene expression databases
Bgee	C9J069.
Family and domain databases
ProtoNet	Search...
Other
GenomeRNAi	389813.
NextBio	103105.

Entry information

Entry name

CI172_HUMAN

Accession

Primary (citable) accession number: C9J069

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 23, 2010
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.