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Protein

Uncharacterized protein C9orf172

Gene

C9orf172

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C9orf172
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:37284. C9orf172.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA165585544.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 976976Uncharacterized protein C9orf172PRO_0000392544Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei129 – 1291PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiC9J069.
PRIDEiC9J069.

PTM databases

PhosphoSiteiC9J069.

Expressioni

Gene expression databases

BgeeiC9J069.

Organism-specific databases

HPAiHPA021200.

Structurei

3D structure databases

ProteinModelPortaliC9J069.
SMRiC9J069. Positions 656-713.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi68 – 422355Pro-richAdd
BLAST

Phylogenomic databases

eggNOGiNOG324574.
GeneTreeiENSGT00390000016543.
HOGENOMiHOG000231560.
InParanoidiC9J069.
OMAiCRRTETL.
OrthoDBiEOG7M0NRT.
PhylomeDBiC9J069.
TreeFamiTF323946.

Sequencei

Sequence statusi: Complete.

C9J069-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTRTDPPDLL VSTVYQDIKV ATPGPASKCS PCERSVARPA EPAPFNKRHC
60 70 80 90 100
RSFDFLEALD GPAMETLPEP PPPESAVPRA RTREAEPRRR ARSKSAPRAP
110 120 130 140 150
PGLTPAPASP PVLPRRGREA QRAARAEASP RREPAYPALR ALANELHPIK
160 170 180 190 200
LQPQRGGPGR VAPLCAAAGR CAPPEPPAGP APHVRCRLDI KPDDAVLQHA
210 220 230 240 250
TRGSRSCGPT EAAHWARPAP QFHGLTVPGP RHMALSRTPT PSDSYCADPR
260 270 280 290 300
AFYCDGPLPG PRDYAERRSL PFTTPPGPTQ FFYTEEPQGF RGSFAASPGP
310 320 330 340 350
TFDAYYPRPY PSEELSGPSP RRMGGYYAGE VRTFPIQEPP SRSYYGEAPR
360 370 380 390 400
AYGLPYGPRY VPEEPRAHST ARPFYTEDFG RYRERDVLAR TYPHPRSSPA
410 420 430 440 450
WADWGPRPYR TLQVVPPSDP DPLLASWHGG TGTSPPRLAT DSRHYSRSWD
460 470 480 490 500
NILAPGPRRE DPLGRGRSYE NLLGREVREP RGVSPEGRRP PVVVNLSTSP
510 520 530 540 550
RRYAALSLSE TSLTEKGRAG EGLGRNWYVT PEITITDNDL RATERPSARA
560 570 580 590 600
WELPGGRTRP PPHAAPDGPT SGRQRSLEQL DELITDLVID SRPTAGQASE
610 620 630 640 650
PAADCLGPQL RRLLDSRPAG SGAPALAPPR SPPASAGSAE EPAAPGEAAD
660 670 680 690 700
ASPEPSADED DLMTCSNARC RRTETMFNAC LYFKSCHSCY TYYCSRLCRR
710 720 730 740 750
EDWDAHKARC VYGRVGSVCR HVLQFCRDSG PVHRAFSRIA RVGFLSRGRG
760 770 780 790 800
VLFLGFPSPG SADNFLRFGL EGLLLSPTYL SLRELATHAA PLGSYARELA
810 820 830 840 850
AAGRLYEPAE CFLLSVSVAV GPGTAPPGTP ALPAPAPRSH GPTVRKFAKV
860 870 880 890 900
ALAAGSPARP PPARSREPDM ETLILTPPPG TAGLDQDGEA GRRAREVAFI
910 920 930 940 950
HIQRELRLRG VFLRHEFPRV YEQLCEFVEA NRRFTPTTIY PTDRRTGRPF
960 970
MCMIMAASEP RALDWVASAN LLDDIM
Length:976
Mass (Da):106,650
Last modified:November 3, 2009 - v1
Checksum:i7DB1CCE956BCA47D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL355987 Genomic DNA. No translation available.
CCDSiCCDS48059.1.
RefSeqiNP_001073951.2. NM_001080482.2.
UniGeneiHs.495485.

Genome annotation databases

EnsembliENST00000436881; ENSP00000412388; ENSG00000232434.
GeneIDi389813.
KEGGihsa:389813.
UCSCiuc011meh.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL355987 Genomic DNA. No translation available.
CCDSiCCDS48059.1.
RefSeqiNP_001073951.2. NM_001080482.2.
UniGeneiHs.495485.

3D structure databases

ProteinModelPortaliC9J069.
SMRiC9J069. Positions 656-713.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiC9J069.

Proteomic databases

PaxDbiC9J069.
PRIDEiC9J069.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000436881; ENSP00000412388; ENSG00000232434.
GeneIDi389813.
KEGGihsa:389813.
UCSCiuc011meh.2. human.

Organism-specific databases

CTDi389813.
GeneCardsiGC09P139738.
HGNCiHGNC:37284. C9orf172.
HPAiHPA021200.
neXtProtiNX_C9J069.
PharmGKBiPA165585544.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG324574.
GeneTreeiENSGT00390000016543.
HOGENOMiHOG000231560.
InParanoidiC9J069.
OMAiCRRTETL.
OrthoDBiEOG7M0NRT.
PhylomeDBiC9J069.
TreeFamiTF323946.

Miscellaneous databases

GenomeRNAii389813.
NextBioi103105.

Gene expression databases

BgeeiC9J069.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCI172_HUMAN
AccessioniPrimary (citable) accession number: C9J069
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: November 3, 2009
Last modified: January 7, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.