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Protein
Submitted name:

Formin-like protein 2

Gene

FMNL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Formin-like protein 2Imported
Gene namesi
Name:FMNL2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000157827.19.
HGNCiHGNC:18267. FMNL2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000157827.

PTM / Processingi

Proteomic databases

MaxQBiC9IZY8.
PaxDbiC9IZY8.
PeptideAtlasiC9IZY8.
PRIDEiC9IZY8.

Expressioni

Gene expression databases

BgeeiENSG00000157827.
ExpressionAtlasiC9IZY8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9IZY8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 382FH2InterPro annotationAdd BLAST382
Domaini414 – 451DADInterPro annotationAdd BLAST38

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili356 – 387Sequence analysisAdd BLAST32

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1923. Eukaryota.
ENOG410Y3DT. LUCA.
GeneTreeiENSGT00760000118986.
HOGENOMiHOG000168240.

Family and domain databases

InterProiView protein in InterPro
IPR014767. DAD_dom.
IPR015425. FH2_Formin.
IPR027656. FMNL2.
PANTHERiPTHR23213:SF180. PTHR23213:SF180. 1 hit.
PfamiView protein in Pfam
PF02181. FH2. 1 hit.
SMARTiView protein in SMART
SM00498. FH2. 1 hit.
PROSITEiView protein in PROSITE
PS51231. DAD. 1 hit.
PS51444. FH2. 1 hit.

Sequencei

Sequence statusi: Complete.

C9IZY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVFNWVALK PNQINGTVFN EIDDERILED LNVDEFEEIF KTKAQGPAID
60 70 80 90 100
LSSSKQKIPQ KGSNKVTLLE ANRAKNLAIT LRKAGKTADE ICKAIHVFDL
110 120 130 140 150
KTLPVDFVEC LMRFLPTENE VKVLRLYERE RKPLENLSDE DRFMMQFSKI
160 170 180 190 200
ERLMQKMTIM AFIGNFAESI QMLTPQLHAI IAASVSIKSS QKLKKILEII
210 220 230 240 250
LALGNYMNSS KRGAVYGFKL QSLDLLLDTK STDRKQTLLH YISNVVKEKY
260 270 280 290 300
HQVSLFYNEL HYVEKAAAVS LENVLLDVKE LQRGMDLTKR EYTMHDHNTL
310 320 330 340 350
LKEFILNNEG KLKKLQDDAK IAQDAFDDVV KYFGENPKTT PPSVFFPVFV
360 370 380 390 400
RFVKAYKQAE EENELRKKQE QALMEKLLEQ EALMEQQDPK SPSHKSKRQQ
410 420 430 440 450
QELIAELRRR QVKDNRHVYE GKDGAIEDII TVLKTVPFTA RTAKRGSRFF
460
CEPVLTEEYH Y
Length:461
Mass (Da):53,384
Last modified:November 3, 2009 - v1
Checksum:i2585A66FF0D55DD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012066 Genomic DNA. No translation available.
AC012443 Genomic DNA. No translation available.
AC093794 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000475377; ENSP00000418959; ENSG00000157827.
UCSCiuc061oqt.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9IZY8_HUMAN
AccessioniPrimary (citable) accession number: C9IZY8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: October 25, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported