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C9IZY8

- C9IZY8_HUMAN

UniProt

C9IZY8 - C9IZY8_HUMAN

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Protein
Submitted name:

Formin-like protein 2

Gene

FMNL2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. cytoskeleton organization Source: InterPro
  2. regulation of cell morphogenesis Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Formin-like protein 2Imported
Gene namesi
Name:FMNL2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:18267. FMNL2.

Expressioni

Gene expression databases

BgeeiC9IZY8.
ExpressionAtlasiC9IZY8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9IZY8.
SMRiC9IZY8. Positions 1-396.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains FH2 (formin homology 2) domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118986.
HOGENOMiHOG000168240.

Family and domain databases

InterProiIPR014767. Diaphanous_autoregulatory.
IPR015425. FH2_Formin.
IPR027656. FMNL2.
[Graphical view]
PANTHERiPTHR23213:SF180. PTHR23213:SF180. 1 hit.
PfamiPF02181. FH2. 1 hit.
[Graphical view]
SMARTiSM00498. FH2. 1 hit.
[Graphical view]
PROSITEiPS51231. DAD. 1 hit.
PS51444. FH2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C9IZY8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPVFNWVALK PNQINGTVFN EIDDERILED LNVDEFEEIF KTKAQGPAID
60 70 80 90 100
LSSSKQKIPQ KGSNKVTLLE ANRAKNLAIT LRKAGKTADE ICKAIHVFDL
110 120 130 140 150
KTLPVDFVEC LMRFLPTENE VKVLRLYERE RKPLENLSDE DRFMMQFSKI
160 170 180 190 200
ERLMQKMTIM AFIGNFAESI QMLTPQLHAI IAASVSIKSS QKLKKILEII
210 220 230 240 250
LALGNYMNSS KRGAVYGFKL QSLDLLLDTK STDRKQTLLH YISNVVKEKY
260 270 280 290 300
HQVSLFYNEL HYVEKAAAVS LENVLLDVKE LQRGMDLTKR EYTMHDHNTL
310 320 330 340 350
LKEFILNNEG KLKKLQDDAK IAQDAFDDVV KYFGENPKTT PPSVFFPVFV
360 370 380 390 400
RFVKAYKQAE EENELRKKQE QALMEKLLEQ EALMEQQDPK SPSHKSKRQQ
410 420 430 440 450
QELIAELRRR QVKDNRHVYE GKDGAIEDII TVLKTVPFTA RTAKRGSRFF
460
CEPVLTEEYH Y
Length:461
Mass (Da):53,384
Last modified:November 3, 2009 - v1
Checksum:i2585A66FF0D55DD2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012066 Genomic DNA. No translation available.
AC012443 Genomic DNA. No translation available.
AC093794 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000475377; ENSP00000418959; ENSG00000157827.
UCSCiuc010fob.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC012066 Genomic DNA. No translation available.
AC012443 Genomic DNA. No translation available.
AC093794 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali C9IZY8.
SMRi C9IZY8. Positions 1-396.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000475377 ; ENSP00000418959 ; ENSG00000157827 .
UCSCi uc010fob.3. human.

Organism-specific databases

HGNCi HGNC:18267. FMNL2.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00760000118986.
HOGENOMi HOG000168240.

Miscellaneous databases

ChiTaRSi FMNL2. human.
NextBioi 35484386.

Gene expression databases

Bgeei C9IZY8.
ExpressionAtlasi C9IZY8. baseline and differential.

Family and domain databases

InterProi IPR014767. Diaphanous_autoregulatory.
IPR015425. FH2_Formin.
IPR027656. FMNL2.
[Graphical view ]
PANTHERi PTHR23213:SF180. PTHR23213:SF180. 1 hit.
Pfami PF02181. FH2. 1 hit.
[Graphical view ]
SMARTi SM00498. FH2. 1 hit.
[Graphical view ]
PROSITEi PS51231. DAD. 1 hit.
PS51444. FH2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiC9IZY8_HUMAN
AccessioniPrimary (citable) accession number: C9IZY8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: October 29, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3