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C9IZY8

- C9IZY8_HUMAN

UniProt

C9IZY8 - C9IZY8_HUMAN

Protein
Submitted name:

Formin-like protein 2

Gene

FMNL2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. cytoskeleton organization Source: InterPro
    2. regulation of cell morphogenesis Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Formin-like protein 2Imported
    Gene namesi
    Name:FMNL2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:18267. FMNL2.

    Expressioni

    Gene expression databases

    ArrayExpressiC9IZY8.
    BgeeiC9IZY8.

    Structurei

    3D structure databases

    ProteinModelPortaliC9IZY8.
    SMRiC9IZY8. Positions 4-396.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains FH2 (formin homology 2) domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000168240.

    Family and domain databases

    InterProiIPR014767. Diaphanous_autoregulatory.
    IPR015425. FH2_Formin.
    IPR027656. FMNL2.
    [Graphical view]
    PANTHERiPTHR23213:SF180. PTHR23213:SF180. 1 hit.
    PfamiPF02181. FH2. 1 hit.
    [Graphical view]
    SMARTiSM00498. FH2. 1 hit.
    [Graphical view]
    PROSITEiPS51231. DAD. 1 hit.
    PS51444. FH2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C9IZY8-1 [UniParc]FASTAAdd to Basket

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    MPVFNWVALK PNQINGTVFN EIDDERILED LNVDEFEEIF KTKAQGPAID    50
    LSSSKQKIPQ KGSNKVTLLE ANRAKNLAIT LRKAGKTADE ICKAIHVFDL 100
    KTLPVDFVEC LMRFLPTENE VKVLRLYERE RKPLENLSDE DRFMMQFSKI 150
    ERLMQKMTIM AFIGNFAESI QMLTPQLHAI IAASVSIKSS QKLKKILEII 200
    LALGNYMNSS KRGAVYGFKL QSLDLLLDTK STDRKQTLLH YISNVVKEKY 250
    HQVSLFYNEL HYVEKAAAVS LENVLLDVKE LQRGMDLTKR EYTMHDHNTL 300
    LKEFILNNEG KLKKLQDDAK IAQDAFDDVV KYFGENPKTT PPSVFFPVFV 350
    RFVKAYKQAE EENELRKKQE QALMEKLLEQ EALMEQQDPK SPSHKSKRQQ 400
    QELIAELRRR QVKDNRHVYE GKDGAIEDII TVLKTVPFTA RTAKRGSRFF 450
    CEPVLTEEYH Y 461
    Length:461
    Mass (Da):53,384
    Last modified:November 3, 2009 - v1
    Checksum:i2585A66FF0D55DD2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012066 Genomic DNA. No translation available.
    AC012443 Genomic DNA. No translation available.
    AC093794 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000475377; ENSP00000418959; ENSG00000157827.
    UCSCiuc010fob.3. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC012066 Genomic DNA. No translation available.
    AC012443 Genomic DNA. No translation available.
    AC093794 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali C9IZY8.
    SMRi C9IZY8. Positions 4-396.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000475377 ; ENSP00000418959 ; ENSG00000157827 .
    UCSCi uc010fob.3. human.

    Organism-specific databases

    HGNCi HGNC:18267. FMNL2.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000168240.

    Miscellaneous databases

    ChiTaRSi FMNL2. human.
    NextBioi 35484386.

    Gene expression databases

    ArrayExpressi C9IZY8.
    Bgeei C9IZY8.

    Family and domain databases

    InterProi IPR014767. Diaphanous_autoregulatory.
    IPR015425. FH2_Formin.
    IPR027656. FMNL2.
    [Graphical view ]
    PANTHERi PTHR23213:SF180. PTHR23213:SF180. 1 hit.
    Pfami PF02181. FH2. 1 hit.
    [Graphical view ]
    SMARTi SM00498. FH2. 1 hit.
    [Graphical view ]
    PROSITEi PS51231. DAD. 1 hit.
    PS51444. FH2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    4. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiC9IZY8_HUMAN
    AccessioniPrimary (citable) accession number: C9IZY8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 3, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3