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Protein
Submitted name:

cAMP-responsive element modulator

Gene

CREM

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
cAMP-responsive element modulatorImported
Gene namesi
Name:CREMImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000095794.19.
HGNCiHGNC:2352. CREM.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000095794.

PTM / Processingi

Proteomic databases

PeptideAtlasiC9IYM9.

Expressioni

Gene expression databases

BgeeiENSG00000095794.
ExpressionAtlasiC9IYM9. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliC9IYM9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 98KIDInterPro annotationAdd BLAST60

Phylogenomic databases

GeneTreeiENSGT00390000008655.
HOGENOMiHOG000007365.

Family and domain databases

InterProiView protein in InterPro
IPR004827. bZIP.
IPR003102. Coactivator_CBP_pKID.
IPR001630. Leuzip_CREB.
PfamiView protein in Pfam
PF02173. pKID. 1 hit.
PRINTSiPR00041. LEUZIPPRCREB.
PROSITEiView protein in PROSITE
PS00036. BZIP_BASIC. 1 hit.
PS50953. KID. 1 hit.

Sequencei

Sequence statusi: Fragment.

C9IYM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMETVESQH DGSITASLTE SKSAHVQTQT GQNSIPALAQ VAAIAETDES
60 70 80 90 100
AESEGVIDSH KRREILSRRP SYRKILNELS SDVPGVPKIE EERSEEEGTP
110 120 130 140 150
PSIATMAVPT SIYQTSTGQY TATGDMPTYQ IRAPTAALPQ GVVMAASPGS
160 170 180
LHSPQQLAEE ATRKRELRLM KNREAAKECR RRKKEY
Length:186
Mass (Da):20,368
Last modified:October 5, 2016 - v8
Checksum:i8CCD052011B34C9F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei186Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117336 Genomic DNA. No translation available.
AL157783 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000487132; ENSP00000418798; ENSG00000095794.
UCSCiuc057ssr.1. human.

Similar proteinsi

Entry informationi

Entry nameiC9IYM9_HUMAN
AccessioniPrimary (citable) accession number: C9IYM9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: October 5, 2016
Last modified: October 25, 2017
This is version 64 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported