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Protein
Submitted name:

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial

Gene

PDK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrialImported
Gene namesi
Name:PDK1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000152256.13
HGNCiHGNC:8809 PDK1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000152256

PTM / Processingi

Proteomic databases

MaxQBiC9IYB4
PeptideAtlasiC9IYB4
PRIDEiC9IYB4

Expressioni

Gene expression databases

BgeeiENSG00000152256
ExpressionAtlasiC9IYB4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliC9IYB4
SMRiC9IYB4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 56BCDHK_Adom3InterPro annotationAdd BLAST56
Domaini56 – 137BCDHK_Adom3InterPro annotationAdd BLAST82

Phylogenomic databases

GeneTreeiENSGT00550000074574
HOGENOMiHOG000164315

Family and domain databases

Gene3Di1.20.140.20, 2 hits
3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR036784 AK/P_DHK_N_sf
IPR018955 BCDHK/PDK_N
IPR036890 HATPase_C_sf
PfamiView protein in Pfam
PF10436 BCDHK_Adom3, 2 hits
SUPFAMiSSF55874 SSF55874, 1 hit
SSF69012 SSF69012, 1 hit

Sequencei

Sequence statusi: Fragment.

C9IYB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQFLDFGSV NACEKTSFMF LRQELPVRLA NIMKEISLLP DNLLRTPSVQ
60 70 80 90 100
LVQSCFTDTV IRIRNRHNDV IPTMAQGVIE YKESFGVDPV TSQNVQYFLD
110 120 130 140 150
RFYMSRISIR MLLNQHSLLF GGKGKGSPSH RKHIGSINPN CNVLEVIKDG
160 170 180 190 200
YENARRLCDL YYINSPELEL EELNAKSPGQ PIQVVYVPSH LYHMVFELFK
210 220
NAMRATMEHH ANRGVYPPIQ VHVTLGNED
Length:229
Mass (Da):26,268
Last modified:November 3, 2009 - v1
Checksum:i9D0493821A0F7CFE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei229Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018712 Genomic DNA No translation available.
AC093818 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000416991; ENSP00000399160; ENSG00000152256
UCSCiuc061psk.1 human

Similar proteinsi

Entry informationi

Entry nameiC9IYB4_HUMAN
AccessioniPrimary (citable) accession number: C9IYB4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health